Search Results - "McGregor, Keith M"
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Integrative learning for population of dynamic networks with covariates
Published in NeuroImage (Orlando, Fla.) (01-08-2021)“…•One of the first integrative methods in literature to jointly estimate a collection of unknown dynamic networks for a group of individuals, guided by…”
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Examination of acute spin exercise on GABA levels in aging and stroke: The EASE study protocol
Published in PloS one (15-07-2024)“…Changes in regional levels of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) may indicate the potential for favorable responses to the…”
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Structural connectivity of Broca's area and medial frontal cortex
Published in NeuroImage (Orlando, Fla.) (01-10-2010)“…Despite over 140years of research on Broca's area, the connections of this region to medial frontal cortex remain unclear. The current study investigates this…”
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Effects of a 12-Week Aerobic Spin Intervention on Resting State Networks in Previously Sedentary Older Adults
Published in Frontiers in psychology (27-11-2018)“…We have previously demonstrated that aerobic exercise improves upper extremity motor function concurrent with changes in motor cortical activity using…”
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Changes in Cortical Activation Patterns in Language Areas following an Aerobic Exercise Intervention in Older Adults
Published in Neural plasticity (01-01-2017)“…Previous work has shown that older adults who evidence increased right inferior frontal gyrus (IFG) activity during language tasks show decreased sematic…”
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Effects of exercise on the sleep microarchitecture in the aging brain: A study on a sedentary sample
Published in Frontiers in systems neuroscience (26-10-2022)“…Having a healthy sleep pattern plays a vital role in one's overall health. Sleep in the elderly is characterized by decreased slow-wave sleep and an increase…”
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Not All Lesioned Tissue Is Equal: Identifying Pericavitational Areas in Chronic Stroke With Tissue Integrity Gradation via T2w T1w Ratio
Published in Frontiers in neuroscience (05-08-2021)“…Stroke-related tissue damage within lesioned brain areas is topologically non-uniform and has underlying tissue composition changes that may have important…”
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The Relationship Between Resting Cerebral Blood Flow, Neurometabolites, Cardio-Respiratory Fitness and Aging-Related Cognitive Decline
Published in Frontiers in psychiatry (09-06-2022)“…Older adults typically experience a decline in cognitive function, but improvements in physical health and lifestyle can be neuroprotective across the human…”
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Functional imaging and related techniques: an introduction for rehabilitation researchers
Published in Journal of rehabilitation research and development (01-01-2010)“…In the rehabilitation arena, a better understanding of how the brain's connections are damaged could help us predict what treatments are best for different…”
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The effect of time since stroke, gender, age, and lesion size on thalamus volume in chronic stroke: a pilot study
Published in Scientific reports (24-11-2020)“…Recent stroke studies have shown that the ipsi-lesional thalamus longitudinally and significantly decreases after stroke in the acute and subacute stages…”
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Physical activity and neural correlates of aging: A combined TMS/fMRI study
Published in Behavioural brain research (12-09-2011)“…► We compare ipsilateral motor activity across age groupings using fMRI and TMS. ► Groups consist of young adults, physically active elderly adults, and…”
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Correcting Task fMRI Signals for Variability in Baseline CBF Improves BOLD-Behavior Relationships: A Feasibility Study in an Aging Model
Published in Frontiers in neuroscience (30-04-2020)“…Blood Oxygen Level Dependent (BOLD) functional MRI is a complex neurovascular signal whose magnitude depends on baseline physiological factors such as cerebral…”
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GABA, Aging and Exercise: Functional and Intervention Considerations
Published in Neuroscience insights (01-01-2024)“…The global growth of an aging population is expected to coincide with an increase in aging-related pathologies, including those related to brain health. Thus,…”
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The relevance of aging-related changes in brain function to rehabilitation in aging-related disease
Published in Frontiers in human neuroscience (27-05-2015)“…The effects of aging on rehabilitation of aging-related diseases are rarely a design consideration in rehabilitation research. In this brief review we present…”
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Internally Guided Lower Limb Movement Recruits Compensatory Cerebellar Activity in People With Parkinson's Disease
Published in Frontiers in neurology (07-06-2019)“…Externally guided (EG) and internally guided (IG) movements are postulated to recruit two parallel neural circuits, in which motor cortical neurons interact…”
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Influences of 12-Week Physical Activity Interventions on TMS Measures of Cortical Network Inhibition and Upper Extremity Motor Performance in Older Adults-A Feasibility Study
Published in Frontiers in aging neuroscience (04-01-2018)“…Data from previous cross-sectional studies have shown that an increased level of physical fitness is associated with improved motor dexterity across the…”
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Context-Dependent Neural Activation: Internally and Externally Guided Rhythmic Lower Limb Movement in Individuals With and Without Neurodegenerative Disease
Published in Frontiers in neurology (02-12-2015)“…Parkinson's disease is a neurodegenerative disorder that has received considerable attention in allopathic medicine over the past decades. However, it is clear…”
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Rostral anterior cingulate connectivity in older adults with subthreshold depressive symptoms: A preliminary study
Published in Aging brain (01-01-2023)“…Subthreshold depressive symptoms are highly prevalent among older adults and are associated with numerous health risks including cognitive decline and…”
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Effects of Combined Aerobic Exercise and Cognitive Training on Verbal Fluency in Older Adults
Published in Gerontology and geriatric medicine (01-01-2020)“…We have previously shown that aerobic exercise improves measures of verbal fluency in older adults, and such an improvement is correlated with improved…”
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Effects of aerobic fitness on aging-related changes of interhemispheric inhibition and motor performance
Published in Frontiers in aging neuroscience (2013)“…Physical fitness has been long associated with maintenance and improvement of motor performance as we age. In particular, measures of psychomotor speed and…”
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