Search Results - "McGregor, I."

The direct actions of cannabidiol and 2-arachidonoyl glycerol at GABAA receptors by Bakas, T., van Nieuwenhuijzen, P.S., Devenish, S.O., McGregor, I.S., Arnold, J.C., Chebib, M.

“…This study reveals a mode of action of CBD at GABAA receptors, in particular at α2-containing receptors that may be relevant to the anticonvulsant and…”
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Oral THC:CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting: a randomised, placebo-controlled, phase II crossover trial by Grimison, P., Mersiades, A., Kirby, A., Lintzeris, N., Morton, R., Haber, P., Olver, I., Walsh, A., McGregor, I., Cheung, Y., Tognela, A., Hahn, C., Briscoe, K., Aghmesheh, M., Fox, P., Abdi, E., Clarke, S., Della-Fiorentina, S., Shannon, J., Gedye, C., Begbie, S., Simes, J., Stockler, M.

“…This multicentre, randomised, double-blinded, placebo-controlled, phase II/III trial aimed to evaluate an oral THC:CBD (tetrahydrocannabinol:cannabidiol)…”
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Cannabis containing equivalent concentrations of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) induces less state anxiety than THC-dominant cannabis by Hutten, Nadia R. P. W., Arkell, T. R., Vinckenbosch, F., Schepers, J., Kevin, R. C., Theunissen, E. L., Kuypers, K. P. C., McGregor, I. S., Ramaekers, J. G.

“…Rationale Delta -9-tetrahydrocannabinol (THC), an active component of cannabis, can cause anxiety in some users during intoxication. Cannabidiol (CBD), another…”
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Body temperature and cardiac changes induced by peripherally administered oxytocin, vasopressin and the non‐peptide oxytocin receptor agonist WAY 267,464: a biotelemetry study in rats by Hicks, C, Ramos, L, Reekie, T, Misagh, G H, Narlawar, R, Kassiou, M, McGregor, I S

“…Background and Purpose There is current interest in oxytocin (OT) as a possible therapeutic in psychiatric disorders. However, the usefulness of OT may be…”
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Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans by Roforth, Matthew M, Fujita, Koji, McGregor, Ulrike I, Kirmani, Salman, McCready, Louise K, Peterson, James M, Drake, Matthew T, Monroe, David G, Khosla, Sundeep

“…Abstract Although aging is associated with a decline in bone formation in humans, the molecular pathways contributing to this decline remain unclear. Several…”
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From ultrasocial to antisocial: a role for oxytocin in the acute reinforcing effects and long‐term adverse consequences of drug use? by McGregor, I S, Callaghan, P D, Hunt, G E

“…Addictive drugs can profoundly affect social behaviour both acutely and in the long‐term. Effects range from the artificial sociability imbued by various…”
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Composition and Use of Cannabis Extracts for Childhood Epilepsy in the Australian Community by Suraev, A., Lintzeris, N., Stuart, J., Kevin, R. C., Blackburn, R., Richards, E., Arnold, J. C., Ireland, C., Todd, L., Allsop, D. J., McGregor, I. S.

“…Recent surveys suggest that many parents are using illicit cannabis extracts in the hope of managing seizures in their children with epilepsy. In the current…”
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Cannabinoid replacement therapy (CRT): Nabiximols (Sativex) as a novel treatment for cannabis withdrawal by Allsop, DJ, Lintzeris, N, Copeland, J, Dunlop, A, McGregor, IS

“…Cannabis is a common recreational drug that is generally considered to have low addictive potential. However, an increasing number of cannabis users are…”
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Resilience and reduced c-Fos expression in P2X7 receptor knockout mice exposed to repeated forced swim test by Boucher, A.A, Arnold, J.C, Hunt, G.E, Spiro, A, Spencer, J, Brown, C, McGregor, I.S, Bennett, M.R, Kassiou, M

“…Abstract There is considerable evidence suggesting genetic factors play an important role in the pathophysiology of depression, possibly by increasing…”
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The Nonpeptide Oxytocin Receptor Agonist WAY 267,464: Receptor-Binding Profile, Prosocial Effects and Distribution of c-Fos Expression in Adolescent Rats by Hicks, C., Jorgensen, W., Brown, C., Fardell, J., Koehbach, J., Gruber, C. W., Kassiou, M., Hunt, G. E., McGregor, I. S.

“…Previous research suggests that the nonpeptide oxytocin receptor (OTR) agonist WAY 267,464 may only partly mimic the effects of oxytocin in rodents. The…”
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S.23.05 MDMA and other party drugs: neural and social effects in rodents by McGregor, I

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‘When a rat smells a cat’: the distribution of Fos immunoreactivity in rat brain following exposure to a predatory odor by Dielenberg, R.A, Hunt, G.E, McGregor, I.S

“…Wistar rats were exposed to a fabric collar that had been worn by a domestic cat. Exposure took place in an open rectangular arena containing a small wooden…”
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Regional c-Fos and FosB/ΔFosB expression associated with chronic methamphetamine self-administration and methamphetamine-seeking behavior in rats by Cornish, J.L, Hunt, G.E, Robins, L, McGregor, I.S

“…Abstract The regional expression of the transcription factors c-Fos and FosB/ΔFosB was examined in rats given acute exposure to intravenous methamphetamine…”
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Cognitive, physical, and mental health outcomes between long-term cannabis and tobacco users by Lovell, M.E., Bruno, R., Johnston, J., Matthews, A., McGregor, I., Allsop, D.J., Lintzeris, N.

“…Cannabis intoxication adversely affects health, yet persistent effects following short-term abstinence in long-term cannabis users are unclear. This…”
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Cat odor, but not trimethylthiazoline (fox odor), activates accessory olfactory and defense-related brain regions in rats by Staples, L.G, McGregor, I.S, Apfelbach, R, Hunt, G.E

“…Abstract Cat odor and trimethylthiazoline (TMT, a component of fox feces) are two stimuli widely used in rodent models of fear and anxiety. Recent studies…”
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Effect of Weld Schedule on the Residual Stress Distribution of Boron Steel Spot Welds by Raath, N. D., Norman, D., McGregor, I., Dashwood, R., Hughes, D. J.

“…Press-hardened boron steel has been utilized in anti-intrusion systems in automobiles, providing high strength and weight-saving potential through gage…”
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A role for oxytocin and 5-HT1A receptors in the prosocial effects of 3,4 methylenedioxymethamphetamine (“ecstasy”) by Thompson, M.R, Callaghan, P.D, Hunt, G.E, Cornish, J.L, McGregor, I.S

“…Abstract The drug 3,4 methylenedioxymethamphetamine (MDMA; ecstasy) has a widely documented ability to increase feelings of love and closeness toward others…”
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Recent trends in primary-care antidepressant prescribing to children and young people: an e-cohort study by John, A, Marchant, A L, Fone, D L, McGregor, J I, Dennis, M S, Tan, J O A, Lloyd, K

“…Concerns relating to increased use of psychotropic medication contrast with those of under-treatment and under-recognition of common mental disorders in…”
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Characterization of Loading Responses and Failure Loci of a Boron Steel Spot Weld by Raath, N. D., Norman, D., McGregor, I., Hepple, S., Dashwood, R., Hughes, D. J.

“…Boron steel, classed as an ultra high-strength steel (UHSS), has been utilized in anti-intrusion systems in automobiles, providing high strength and…”
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Evidence for an Interaction between CB1 Cannabinoid and Melanocortin MCR-4 Receptors in Regulating Food Intake by Verty, A. N. A, McFarlane, J. R, McGregor, I. S, Mallet, P. E

“…Melanocortin receptor 4 (MCR4) and CB1 cannabinoid receptors independently modulate food intake. Although an interaction between the cannabinoid and…”
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