Search Results - "McGregor, E"

basin%Ro: A vitrinite reflectance model derived from basin and laboratory data by Nielsen, S. B., Clausen, O. R., McGregor, E.

“…The combination of vitrinite reflectance, apatite fission track and present‐day borehole temperature data is very useful when performing tectonic and thermal…”
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Optogenetic restoration of retinal ganglion cell activity in the living primate by McGregor, Juliette E., Godat, Tyler, Dhakal, Kamal R., Parkins, Keith, Strazzeri, Jennifer M., Bateman, Brittany A., Fischer, William S., Williams, David R., Merigan, William H.

“…Optogenetic therapies for vision restoration aim to confer intrinsic light sensitivity to retinal ganglion cells when photoreceptors have degenerated and light…”
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IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesis by McGregor, Narelle E., Murat, Melissa, Elango, Jeevithan, Poulton, Ingrid J., Walker, Emma C., Crimeen-Irwin, Blessing, Ho, Patricia W.M., Gooi, Jonathan H., Martin, T. John, Sims, Natalie A.

“…Interleukin 6 (IL-6) supports development of bone-resorbing osteoclasts by acting early in the osteoblast lineage via membrane-bound (cis) or soluble (trans)…”
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Functional architecture of the foveola revealed in the living primate by McGregor, Juliette E, Yin, Lu, Yang, Qiang, Godat, Tyler, Huynh, Khang T, Zhang, Jie, Williams, David R, Merigan, William H

“…The primate foveola, with its high cone density and magnified cortical representation, is exquisitely specialized for high-resolution spatial vision. However,…”
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STAT3 Hyperactivation Due to SOCS3 Deletion in Murine Osteocytes Accentuates Responses to Exercise‐ and Load‐Induced Bone Formation by McGregor, Narelle E, Walker, Emma C, Chan, Audrey SM, Poulton, Ingrid J, Cho, Ellie H‐J, Windahl, Sara H, Sims, Natalie A

“…ABSTRACT Cortical bone develops and changes in response to mechanical load, which is sensed by bone‐embedded osteocytes. The bone formation response to load…”
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Small RNA Profiling of Cucurbit Yellow Stunting Disorder Virus from Susceptible and Tolerant Squash ( Cucurbita pepo ) Lines by Kavalappara, Saritha Raman, Bag, Sudeep, Luckew, Alex, McGregor, Cecilia E

“…RNA silencing is a crucial mechanism of the antiviral immunity system in plants. Small RNAs guide Argonaut proteins to target viral RNA or DNA, preventing…”
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Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis by Ng, Benjamin, Widjaja, Anissa A., Viswanathan, Sivakumar, Dong, Jinrui, Chothani, Sonia P., Lim, Stella, Shekeran, Shamini G., Tan, Jessie, McGregor, Narelle E., Walker, Emma C., Sims, Natalie A., Schafer, Sebastian, Cook, Stuart A.

“…Loss of function (LOF) in IL11RA infers IL11 signaling as important for fertility, fibrosis, inflammation and incompletely penetrant craniosynostosis. The…”
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Foraging rates of ram‐filtering North Atlantic right whales by Hoop, Julie Marie, Nousek‐McGregor, Anna E., Nowacek, Douglas P., Parks, Susan E., Tyack, Peter, Madsen, Peter Teglberg, Goldbogen, Jeremy

“…North Atlantic right whales spend their summer months foraging primarily in American and Canadian Atlantic waters on high‐energy‐density prey. Here, they…”
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Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice by Walker, Emma C, McGregor, Narelle E, Poulton, Ingrid J, Solano, Melissa, Pompolo, Sueli, Fernandes, Tania J, Constable, Matthew J, Nicholson, Geoff C, Zhang, Jian-Guo, Nicola, Nicos A, Gillespie, Matthew T, Martin, T John, Sims, Natalie A

“…Effective osteoporosis therapy requires agents that increase the amount and/or quality of bone. Any modification of osteoclast-mediated bone resorption by…”
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Association of daily composition of physical activity and sedentary behaviour with incidence of cardiovascular disease in older adults by Yerramalla, Manasa S, McGregor, Duncan E, van Hees, Vincent T, Fayosse, Aurore, Dugravot, Aline, Tabak, Adam G, Chen, Mathilde, Chastin, Sebastien F M, Sabia, Séverine

“…Moderate-to-vigorous physical activity (MVPA) is proposed as key for cardiovascular diseases (CVD) prevention. At older ages, the role of sedentary behaviour…”
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The Primary Function of gp130 Signaling in Osteoblasts Is To Maintain Bone Formation and Strength, Rather Than Promote Osteoclast Formation by Johnson, Rachelle W, Brennan, Holly J, Vrahnas, Christina, Poulton, Ingrid J, McGregor, Narelle E, Standal, Therese, Walker, Emma C, Koh, Thuan‐Tzen, Nguyen, Huynh, Walsh, Nicole C, Forwood, Mark R, Martin, T John, Sims, Natalie A

“…ABSTRACT Interleukin‐6 (IL‐6) family cytokines act via gp130 in the osteoblast lineage to stimulate the formation of osteoclasts (bone resorbing cells) and the…”
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Contrasting roles of leukemia inhibitory factor in murine bone development and remodeling involve region-specific changes in vascularization by Poulton, Ingrid J, McGregor, Narelle E, Pompolo, Sueli, Walker, Emma C, Sims, Natalie A

“…We describe here distinct functions of leukemia inhibitory factor (LIF) in bone development/growth and adult skeletal homeostasis. In the growth plate and…”
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Cardiotrophin‐1 Is an Osteoclast‐Derived Stimulus of Bone Formation Required for Normal Bone Remodeling by Walker, Emma C, McGregor, Narelle E, Poulton, Ingrid J, Pompolo, Sueli, Allan, Elizabeth H, Quinn, Julian MW, Gillespie, Matthew T, Martin, T John, Sims, Natalie A

“…Cardiotrophin (CT‐1) signals through gp130 and the LIF receptor (LIFR) and plays a major role in cardiac, neurological, and liver biology. We report here that…”
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In vivo chromatic and spatial tuning of foveolar retinal ganglion cells in Macaca fascicularis by Godat, Tyler, Cottaris, Nicolas P, Patterson, Sara, Kohout, Kendall, Parkins, Keith, Yang, Qiang, Strazzeri, Jennifer M, McGregor, Juliette E, Brainard, David H, Merigan, William H, Williams, David R

“…The primate fovea is specialized for high acuity chromatic vision, with the highest density of cone photoreceptors and a disproportionately large…”
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Optogenetic therapy restores retinal activity in primate for at least a year following photoreceptor ablation by McGregor, Juliette E., Kunala, Karteek, Xu, Zhengyang, Murphy, Peter J., Godat, Tyler, Strazzeri, Jennifer M., Bateman, Brittany A., Fischer, William S., Parkins, Keith, Chu, Colin J., Puthussery, Teresa, Williams, David R., Merigan, William H.

“…All retina-based vision restoration approaches rely on the assumption that photoreceptor loss does not preclude reactivation of the remaining retinal…”
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EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis by Tonna, Stephen, Takyar, Farzin M., Vrahnas, Christina, Crimeen‐Irwin, Blessing, Ho, Patricia W. M., Poulton, Ingrid J., Brennan, Holly J., McGregor, Narelle E., Allan, Elizabeth H., Nguyen, Huynh, Forwood, Mark R., Tatarczuch, Liliana, Mackie, Eleanor J., Martin, T. John, Sims, Natalie A.

“…Cells that form bone (osteoblasts) express both ephrinB2 and EphB4, and previous work has shown that pharmacological inhibition of the eph‐rinB2/EphB4…”
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Cortical bone maturation in mice requires SOCS3 suppression of gp130/STAT3 signalling in osteocytes by Walker, Emma C, Truong, Kim, McGregor, Narelle E, Poulton, Ingrid J, Isojima, Tsuyoshi, Gooi, Jonathan H, Martin, T John, Sims, Natalie A

“…Bone strength is determined by its dense cortical shell, generated by unknown mechanisms. Here we use the mouse, with delayed cortical bone consolidation, to…”
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Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6 by Cho, Dae-Chul, Brennan, Holly J., Johnson, Rachelle W., Poulton, Ingrid J., Gooi, Jonathan H., Tonkin, Brett A., McGregor, Narelle E., Walker, Emma C., Handelsman, David J., Martin, T. J., Sims, Natalie A.

“…Long bone strength is determined by its outer shell (cortical bone), which forms by coalescence of thin trabeculae at the metaphysis (corticalization), but the…”
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Cox regression survival analysis with compositional covariates: Application to modelling mortality risk from 24-h physical activity patterns by McGregor, DE, Palarea-Albaladejo, J, Dall, PM, Hron, K, Chastin, SFM

“…Survival analysis is commonly conducted in medical and public health research to assess the association of an exposure or intervention with a hard end outcome…”
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GRANADA consensus on analytical approaches to assess associations with accelerometer-determined physical behaviours (physical activity, sedentary behaviour and sleep) in epidemiological studies by Migueles, Jairo H, Aadland, Eivind, Andersen, Lars Bo, Brønd, Jan Christian, Chastin, Sebastien F, Hansen, Bjørge H, Konstabel, Kenn, Kvalheim, Olav Martin, McGregor, Duncan E, Rowlands, Alex V, Sabia, Séverine, van Hees, Vincent T, Walmsley, Rosemary, Ortega, Francisco B

“…The inter-relationship between physical activity, sedentary behaviour and sleep (collectively defined as physical behaviours) is of interest to researchers…”
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