Search Results - "McGrath, Kristine C.Y"

Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-Mediated Transport of HDL by Lim, Hwee Ying, Thiam, Chung Hwee, Yeo, Kim Pin, Bisoendial, Radjesh, Hii, Chung Shii, McGrath, Kristine C.Y., Tan, Kar Wai, Heather, Alison, Alexander, J. Steven Jonathan, Angeli, Veronique

“…Removal of cholesterol from peripheral tissues to the bloodstream via reverse cholesterol transport (RCT) is a process of major biological importance. Here we…”
Get full text

Estrogen Receptor Control of Atherosclerotic Calcification and Smooth Muscle Cell Osteogenic Differentiation by McRobb, Lucinda S, McGrath, Kristine C.Y, Tsatralis, Tania, Liong, Eleanore C, Tan, Joanne T.M, Hughes, Gillian, Handelsman, David J, Heather, Alison K

“…OBJECTIVE—Vascular calcification is associated with increased risk of myocardial infarction and stroke. The objective of this work was to examine the ability…”
Get full text

A sex-specific role for androgens in angiogenesis by Sieveking, Daniel P, Lim, Patrick, Chow, Renée W Y, Dunn, Louise L, Bao, Shisan, McGrath, Kristine C Y, Heather, Alison K, Handelsman, David J, Celermajer, David S, Ng, Martin K C

“…Mounting evidence suggests that in men, serum levels of testosterone are negatively correlated to cardiovascular and all-cause mortality. We studied the role…”
Get full text

Attenuation of Liver Pro-Inflammatory Responses by Zingiber officinale via Inhibition of NF-kappa B Activation in High-Fat Diet-Fed Rats by Li, Xiao-Hong, McGrath, Kristine C-Y, Nammi, Srinivas, Heather, Alison K., Roufogalis, Basil D.

“…:  The aim of this study was to investigate whether treatment with a ginger (Zingiber officinale) extract of high‐fat diet (HFD)‐fed rats suppresses Nuclear…”
Get full text

High glucose alters matrix metalloproteinase expression in two key vascular cells: potential impact on atherosclerosis in diabetes by Death, Alison K., Fisher, Elizabeth J., McGrath, Kristine C.Y., Yue, Dennis K.

“…Diabetes is a major risk factor for atherosclerosis. Hyperglycemia is an underlying contributing factor; however, the mechanisms that mediate the vascular…”
Get full text

Inhibitory Effect of a French Maritime Pine Bark Extract-Based Nutritional Supplement on TNF-α-Induced Inflammation and Oxidative Stress in Human Coronary Artery Endothelial Cells by Heather, Alison K., McRobb, Lucinda S., Li, Xiao-Hong, McGrath, Kristine C. Y.

“…Oxidative stress and inflammation, leading to endothelial dysfunction, contribute to the pathogenesis of atherosclerosis. The popularity of natural product…”
Get full text

Apolipoporotein A-I mimetic peptides improved insulin sensitivity in high fat diet fed mice by McGrath, Kristine C.Y, Li, Xiaohong, Heather, Alison K

Get full text

Tetrahydrogestrinone Is a Potent Androgen and Progestin by Death, Alison K., McGrath, Kristine C. Y., Kazlauskas, Rymantas, Handelsman, David J.

“…Tetrahydrogestrinone (THG) was recently identified as a novel steroid used illicitly to improve athletic performance. Although its structure is closely related…”
Get full text

Nitroglycerin upregulates matrix metalloproteinase expression by human macrophages by Death, Alison K, Nakhla, Shirley, McGrath, Kristine C.Y, Martell, Sally, Yue, Dennis K, Jessup, Wendy, Celermajer, David S

“…This study aimed to determine whether nitroglycerin (NTG) treatment affects matrix metalloproteinase (MMP) gene expression and activities in human macrophages…”
Get full text

Corrigendum to "Inhibitory Effect of a French Maritime Pine Bark Extract-Based Nutritional Supplement on TNF- [alpha]-Induced Inflammation and Oxidative Stress in Human Coronary Artery Endothelial Cells." by McGrath, Kristine C.Y, Gangoda, Sumudu V.S, Li, Xiao-Hong, McRobb, Lucinda S, Heather, Alison K

Get full text

Androgen Bioassay for the Detection of Nonlabeled Androgenic Compounds in Nutritional Supplements by Cooper, Elliot R, McGrath, Kristine C Y, Li, XiaoHong, Heather, Alison K

“…Both athletes and the general population use nutritional supplements. Athletes often turn to supplements hoping that consuming the supplement will help them be…”
Get more information

Attenuation of Proinflammatory Responses by S-[6]-Gingerol via Inhibition of ROS/NF-Kappa B/COX2 Activation in HuH7 Cells by McGrath, Kristine C. Y., Li, Yi-Ming, Li, Xiao-Hong, Heather, Alison K., Roufogalis, Basil D., Duke, Colin C., Tran, Van H.

“…Introduction. Hepatic inflammation underlies the pathogenesis of chronic diseases such as insulin resistance and type 2 diabetes mellitus. S-[6]-Gingerol has…”
Get full text

In vitro androgen bioassays as a detection method for designer androgens by Cooper, Elliot R, McGrath, Kristine C Y, Heather, Alison K

“…Androgens are the class of sex steroids responsible for male sexual characteristics, including increased muscle mass and decreased fat mass. Illicit use of…”
Get full text

Dihydrotestosterone Promotes Vascular Cell Adhesion Molecule-1 Expression in Male Human Endothelial Cells via a Nuclear Factor-κB-Dependent Pathway by Death, Alison K, McGrath, Kristine C. Y, Sader, Mark A, Nakhla, Shirley, Jessup, Wendy, Handelsman, David J, Celermajer, David S

“…There exists a striking gender difference in atherosclerotic vascular disease. For decades, estrogen was considered atheroprotective; however, an alternative…”
Get full text

The use of tandem yeast and mammalian cell in vitro androgen bioassays to detect androgens in internet‐sourced sport supplements by Cooper, Elliot R., McGrath, Kristine C.Y., Li, Xiaohong, Akram, Omar, Kasz, Robert, Kazlauskas, Rymantas, McLeod, Malcolm D., Handelsman, David J., Heather, Alison K.

“…Sport supplements containing steroids never approved for therapeutic use have the potential for abuse by athletes. Most are marketed online and may contain…”
Get full text

Endoplasmic Reticulum Stress in Inflammatory Disease by McGrath, Kristine C. Y, Heather, Alison K

Get full text

TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer by SUNDE, Margaret, MCGRATH, Kristine C. Y, YOUNG, Lei, MATTHEWS, Jacqueline M, CHUA, Elizabeth L, MACKAY, Joel P, DEATH, Alison K

“…A novel gene, thyroid cancer 1 (TC-1), was found recently to be overexpressed in thyroid cancer. TC-1 shows no homology to any of the known thyroid…”
Get full text

A sex-specific role for androgens in angiogenesis by Sieveking, Daniel P., Lim, Patrick, Chow, Renée W.Y., Dunn, Louise L., Bao, Shisan, McGrath, Kristine C.Y., Heather, Alison K., Handelsman, David J., Celermajer, David S., Ng, Martin K.C.

Get full text

Identification of a Calcium Signalling Pathway of S-[6]-Gingerol in HuH-7 Cells by Li, Xiao-Hong, McGrath, Kristine C. Y., Tran, Van H., Li, Yi-Ming, Mandadi, Sravan, Duke, Colin C., Heather, Alison K., Roufogalis, Basil D.

“…Calcium signals in hepatocytes control cell growth, proliferation, and death. Members of the transient receptor potential (TRP) cation channel superfamily are…”
Get full text

Valproate is an anti-androgen and anti-progestin by Death, Alison K., McGrath, Kristine C.Y., Handelsman, David J.

“…Anti-convulsant treatment is associated with a high prevalence of reproductive dysfunction compared with age-matched non-epileptics. We examined the widely…”
Get full text