Search Results - "McGlone, Emma Rose"

Sleeve gastrectomy causes weight‐loss independent improvements in hepatic steatosis by McGlone, Emma Rose, Siebert, Matthieu, Dore, Marian, Hope, David C. D., Davies, Iona, Owen, Bryn, Khoo, Bernard, Goldin, Rob, Carling, Dave, Bloom, Stephen, Le Gall, Maude, Tan, Tricia M‐M.

“…Background and Aims Sleeve gastrectomy (VSG) leads to improvement in hepatic steatosis, associated with weight loss. The aims of this study were to investigate…”
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Bariatric surgery for patients with type 2 diabetes mellitus requiring insulin: Clinical outcome and cost-effectiveness analyses by McGlone, Emma Rose, Carey, Iain, Veličković, Vladica, Chana, Prem, Mahawar, Kamal, Batterham, Rachel L, Hopkins, James, Walton, Peter, Kinsman, Robin, Byrne, James, Somers, Shaw, Kerrigan, David, Menon, Vinod, Borg, Cynthia, Ahmed, Ahmed, Sgromo, Bruno, Cheruvu, Chandra, Bano, Gul, Leonard, Catherine, Thom, Howard, le Roux, Carel W, Reddy, Marcus, Welbourn, Richard, Small, Peter, Khan, Omar A

“…Although bariatric surgery is well established as an effective treatment for patients with obesity and type 2 diabetes mellitus (T2DM), there exists reluctance…”
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Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice with diet-induced obesity by McGlone, Emma Rose, Hope, David C.D., Davies, Iona, Dore, Marian, Goldin, Rob, Jones, Ben, Liu, Zhigang, Li, Jia V., Vorkas, Panagiotis A., Khoo, Bernard, Carling, David, Minnion, James, Bloom, Stephen R., Tan, Tricia M-M.

“…Co-agonists at the glucagon-like peptide-1 and glucagon receptors (GLP1R/GCGR) show promise as treatments for metabolic dysfunction-associated steatotic liver…”
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Receptor Activity-Modifying Protein 2 (RAMP2) alters glucagon receptor trafficking in hepatocytes with functional effects on receptor signalling by McGlone, Emma Rose, Manchanda, Yusman, Jones, Ben, Pickford, Phil, Inoue, Asuka, Carling, David, Bloom, Stephen R., Tan, Tricia, Tomas, Alejandra

“…Receptor Activity-Modifying Protein 2 (RAMP2) is a chaperone protein which allosterically binds to and interacts with the glucagon receptor (GCGR). The aims of…”
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Urogenital function following laparoscopic and open rectal cancer resection: a comparative study by McGlone, Emma Rose, Khan, Omar, Flashman, Karen, Khan, Jim, Parvaiz, Amjad

“…Background Sexual and urinary dysfunction is an established risk after pelvic surgery. Studies examining sexual and urinary function following laparoscopic and…”
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Hepatocyte cholesterol content modulates glucagon receptor signalling by McGlone, Emma Rose, Ansell, T. Bertie, Dunsterville, Cecilia, Song, Wanling, Carling, David, Tomas, Alejandra, Bloom, Stephen R., Sansom, Mark S.P., Tan, Tricia, Jones, Ben

“…To determine whether glucagon receptor (GCGR) actions are modulated by cellular cholesterol levels. We determined the effects of experimental cholesterol…”
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Cost-effectiveness of superabsorbent wound dressing versus standard of care in patients with moderate-to-highly exuding leg ulcers by Veličković, Vladica M, Chadwick, Paul, Rippon, Mark G, Ilić, Ivana, McGlone, Emma Rose, Gebreslassie, Mihretab, Csernus, Mariann, Streit, Iris, Bordeanu, Adriana, Kaspar, Daniela, Linder, Jörg, Smola, Hans

“…Objective: To determine the cost-effectiveness/utility of a superabsorbent wound dressing (Zetuvit Plus Silicone) versus the current standard of care (SoC)…”
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Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist by Pickford, Phil, Lucey, Maria, Rujan, Roxana-Maria, McGlone, Emma Rose, Bitsi, Stavroula, Ashford, Fiona B., Corrêa, Ivan R., Hodson, David J., Tomas, Alejandra, Deganutti, Giuseppe, Reynolds, Christopher A., Owen, Bryn M., Tan, Tricia M., Minnion, James, Jones, Ben, Bloom, Stephen R.

“…Glucagon-like peptide-1 and glucagon receptor (GLP-1R/GCGR) co-agonism can maximise weight loss and improve glycaemic control in type 2 diabetes and obesity…”
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Is bariatric surgery in patients following renal transplantation safe and effective? A Best Evidence Topic by Hadjievangelou, Nancy, Dr, Kulendran, Myutan, Mr, McGlone, Emma Rose, Ms, Reddy, Marcus, Mr, Khan, Omar A., Mr

“…Abstract Obesity is common amongst patients with renal transplants (RT). It is associated not only with generic obesity-related complications including…”
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Roux-en-Y gastric bypass or sleeve gastrectomy for obstructive sleep apnea: A systematic review and meta-analysis by Al-Rubaye, Hussein, McGlone, Emma Rose, Farzaneh, Borna, Mustafa, Livyar, Johnson, Mae, Kayal, Ajit, English, Caroline-Louise, Kaur, Vasha, Kalendran, Myutan, Reddy, Marcus, Khan, Omar A.

“…Bariatric surgery has been shown to be an effective method of treatment for obstructive sleep apnea (OSA) with long-term benefits, however, the mechanisms of…”
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Bile acids and the metabolic syndrome by McGlone, Emma Rose, Bloom, Stephen R

“…Bile acids have important roles in the regulation of lipid, glucose and energy metabolism. Metabolic diseases linked to obesity, including type 2 diabetes…”
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Glucagon resistance and metabolic-associated steatotic liver disease: a review of the evidence by McGlone, Emma Rose, Bloom, Stephen R, Tan, Tricia M-M

“…Metabolic-associated steatotic liver disease (MASLD) is closely associated with obesity. MASLD affects over 1 billion adults globally but there are few…”
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Lipid regulation of the glucagon receptor family by Oqua, Affiong Ika, Manchanda, Yusman, McGlone, Emma Rose, Jones, Ben, Rouse, Sarah, Tomas, Alejandra

“…The glucagon receptor family are typical class B1 G protein-coupled receptors (GPCRs) with important roles in metabolism, including the control of pancreas,…”
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Peer review report 2 on “Laparoscopy versus Laparotomy for the management of penetrating abdominal trauma: A systematic review and meta-analysis” by McGlone, Emma Rose

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Glucagon-based therapy for people with diabetes and obesity: What is the sweet spot? by McGlone, Emma Rose, Tan, Tricia M.-M.

“…People with obesity and type 2 diabetes have a high prevalence of metabolic-associated steatotic liver disease, hyperlipidemia and cardiovascular disease…”
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Adjunctive liraglutide treatment in patients with persistent or recurrent type 2 diabetes after metabolic surgery (GRAVITAS): a randomised, double-blind, placebo-controlled trial by Miras, Alexander Dimitri, Pérez-Pevida, Belén, Aldhwayan, Madhawi, Kamocka, Anna, McGlone, Emma Rose, Al-Najim, Werd, Chahal, Harvinder, Batterham, Rachel L, McGowan, Barbara, Khan, Omar, Greener, Veronica, Ahmed, Ahmed R, Petrie, Aviva, Scholtz, Samantha, Bloom, Stephen R, Tan, Tricia M

“…Many patients with type 2 diabetes do not achieve sustained diabetes remission after metabolic (bariatric) surgery for the treatment of obesity. Liraglutide, a…”
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Long-Term Quality of Life Outcomes After Laparoscopic Sleeve Gastrectomy and Roux-en-Y Gastric Bypass—a Comparative Study by Fiorani, Cristina, Coles, Sophie R., Kulendran, Myutan, McGlone, Emma Rose, Reddy, Marcus, Khan, Omar A.

“…Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) have been shown to improve metabolic comorbidities as well as quality of life (QoL) in the obese…”
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Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptors by Jones, Ben, McGlone, Emma Rose, Fang, Zijian, Pickford, Phil, Corrêa, Ivan R., Oishi, Atsuro, Jockers, Ralf, Inoue, Asuka, Kumar, Sunil, Görlitz, Frederik, Dunsby, Chris, French, Paul M.W., Rutter, Guy A., Tan, Tricia, Tomas, Alejandra, Bloom, Stephen R.

“…Receptors for the peptide hormones glucagon-like peptide-1 (GLP-1R), glucose-dependent insulinotropic polypeptide (GIPR), and glucagon (GCGR) are important…”
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Antral resection versus antral preservation during laparoscopic sleeve gastrectomy for severe obesity: Systematic review and meta-analysis by McGlone, Emma Rose, Gupta, Ajay K., Reddy, Marcus, Khan, Omar A.

“…Although laparoscopic sleeve gastrectomy is an established operation for severe obesity, there is controversy regarding the extent to which the antrum is…”
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Analysis of the effect of staple line reinforcement on leaking and bleeding after sleeve gastrectomy from the UK National Bariatric Surgery Registry by Niaz, Osamah, Askari, Alan, Currie, Andrew, McGlone, Emma Rose, Zakeri, Roxanna, Khan, Omar, Welbourn, Richard, Pring, Chris, Small, Peter, Al‐Taan, Omer, Mahawar, Kamal, Mamidanna, Ravikrishna

“…Introduction Sleeve gastrectomy (SG) is currently the most frequently performed procedure for obesity worldwide. Staple line reinforcement (SLR) has been…”
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