Search Results - "McGinty, Gabrielle"

Understanding the Molecular Mechanisms of Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD): Towards the Development of SSADH-Targeted Medicine by Lee, Henry H C, McGinty, Gabrielle E, Pearl, Phillip L, Rotenberg, Alexander

“…Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a rare genetic disorder caused by inefficient metabolic breakdown of the major inhibitory…”
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ALDH5A1-deficient iPSC-derived excitatory and inhibitory neurons display cell type specific alterations by Afshar-Saber, Wardiya, Teaney, Nicole A, Winden, Kellen D, Jumo, Hellen, Shi, Xutong, McGinty, Gabrielle, Hubbs, Jed, Chen, Cidi, Tokatly Latzer, Itay, Gasparoli, Federico, Ebrahimi-Fakhari, Darius, Buttermore, Elizabeth D, Roullet, Jean-Baptiste, Pearl, Phillip L, Sahin, Mustafa

“…Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a neurometabolic disorder caused by ALDH5A1 mutations presenting with autism and epilepsy. SSADHD…”
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Intermittent Ethanol Access Increases Sensitivity to Social Defeat Stress by Nennig, Sadie E., Fulenwider, Hannah D., Eskew, Jacob E., Whiting, Kimberly E., Cotton, Mallory R., McGinty, Gabrielle E., Solomon, Matthew G., Schank, Jesse R.

“…Background Comorbidity between alcoholism and depression is extremely common. Recent evidence supports a relationship between alcohol exposure and stress…”
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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Tokatly Latzer, Itay, Roullet, Jean-Baptiste, Afshar-Saber, Wardiya, Lee, Henry H C, Bertoldi, Mariarita, McGinty, Gabrielle E, DiBacco, Melissa L, Arning, Erland, Tsuboyama, Melissa, Rotenberg, Alexander, Opladen, Thomas, Jeltsch, Kathrin, García-Cazorla, Àngels, Juliá-Palacios, Natalia, Gibson, K Michael, Sahin, Mustafa, Pearl, Phillip L

“…Succinic semialdehyde dehydrogenase deficiency (SSADHD) represents a model neurometabolic disease at the fulcrum of translational research within the Boston…”
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