Search Results - "McGinnity, Colm J"

Attenuation of proliferation in oligodendrocyte precursor cells by activated microglia by Taylor, Deanna L., Pirianov, Grisha, Holland, Samantha, McGinnity, Colm J., Norman, Adele L., Reali, Camilla, Diemel, Lara T., Gveric, Djordje, Yeung, Davy, Mehmet, Huseyin

“…Activated microglia can influence the survival of neural cells through the release of cytotoxic factors. Here, we investigated the interaction between…”
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N-methyl-D-aspartate receptor availability in first-episode psychosis: a PET-MR brain imaging study by Beck, Katherine, Arumuham, Atheeshaan, Veronese, Mattia, Santangelo, Barbara, McGinnity, Colm J., Dunn, Joel, McCutcheon, Robert A., Kaar, Stephen J., Singh, Nisha, Pillinger, Toby, Borgan, Faith, Stone, James, Jauhar, Sameer, Sementa, Teresa, Turkheimer, Federico, Hammers, Alexander, Howes, Oliver D.

“…N-methyl-D-aspartate receptor (NMDAR) hypofunction is hypothesised to underlie psychosis but this has not been tested early in illness. To address this, we…”
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A Retrospective Case Series Analysis of the Relationship Between Phenylalanine: Tyrosine Ratio and Cerebral Glucose Metabolism in Classical Phenylketonuria and Hyperphenylalaninemia by McGinnity, Colm J., Riaño Barros, Daniela A., Guedj, Eric, Girard, Nadine, Symeon, Christopher, Walker, Helen, Barrington, Sally F., Summers, Mary, Pitkanen, Mervi, Rahman, Yusof

“…We retrospectively examined the relationship between blood biomarkers, in particular the historical mean phenylalanine to tyrosine (Phe:Tyr) ratio, and…”
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PET image enhancement using artificial intelligence for better characterization of epilepsy lesions by Flaus, Anthime, Deddah, Tahya, Reilhac, Anthonin, Leiris, Nicolas De, Janier, Marc, Merida, Ines, Grenier, Thomas, McGinnity, Colm J., Hammers, Alexander, Lartizien, Carole, Costes, Nicolas

“…Introduction [ 18 F]fluorodeoxyglucose ([ 18 F]FDG) brain PET is used clinically to detect small areas of decreased uptake associated with epileptogenic…”
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Error propagation analysis of seven partial volume correction algorithms for [18F]THK-5351 brain PET imaging by Oyama, Senri, Hosoi, Ayumu, Ibaraki, Masanobu, McGinnity, Colm J., Matsubara, Keisuke, Watanuki, Shoichi, Watabe, Hiroshi, Tashiro, Manabu, Shidahara, Miho

“…Background Novel partial volume correction (PVC) algorithms have been validated by assuming ideal conditions of image processing; however, in real clinical PET…”
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Quantification of opioid receptor availability following spontaneous epileptic seizures: Correction of [11C]diprenorphine PET data for the partial-volume effect by McGinnity, Colm J., Shidahara, Miho, Feldmann, Maria, Keihaninejad, Shiva, Riaño Barros, Daniela A., Gousias, Ioannis S., Duncan, John S., Brooks, David J., Heckemann, Rolf A., Turkheimer, Federico E., Hammers, Alexander, Koepp, Matthias J.

“…Previous positron emission tomography (PET) studies in refractory temporal lobe epilepsy (TLE) using the non-selective opioid receptor antagonist…”
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Mapping neurotransmitter systems to the structural and functional organization of the human neocortex by Hansen, Justine Y., Shafiei, Golia, Markello, Ross D., Smart, Kelly, Cox, Sylvia M. L., Nørgaard, Martin, Beliveau, Vincent, Wu, Yanjun, Gallezot, Jean-Dominique, Aumont, Étienne, Servaes, Stijn, Scala, Stephanie G., DuBois, Jonathan M., Wainstein, Gabriel, Bezgin, Gleb, Funck, Thomas, Schmitz, Taylor W., Spreng, R. Nathan, Galovic, Marian, Koepp, Matthias J., Duncan, John S., Coles, Jonathan P., Fryer, Tim D., Aigbirhio, Franklin I., McGinnity, Colm J., Hammers, Alexander, Soucy, Jean-Paul, Baillet, Sylvain, Guimond, Synthia, Hietala, Jarmo, Bedard, Marc-André, Leyton, Marco, Kobayashi, Eliane, Rosa-Neto, Pedro, Ganz, Melanie, Knudsen, Gitte M., Palomero-Gallagher, Nicola, Shine, James M., Carson, Richard E., Tuominen, Lauri, Dagher, Alain, Misic, Bratislav

“…Neurotransmitter receptors support the propagation of signals in the human brain. How receptor systems are situated within macro-scale neuroanatomy and how…”
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Simplifying [18F]GE-179 PET: are both arterial blood sampling and 90-min acquisitions essential? by McGinnity, Colm J., Riaño Barros, Daniela A., Trigg, William, Brooks, David J., Hinz, Rainer, Duncan, John S., Koepp, Matthias J., Hammers, Alexander

“…Introduction The NMDA receptor radiotracer [ 18 F]GE-179 has been used with 90-min scans and arterial plasma input functions. We explored whether (1) arterial…”
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On brain atlas choice and automatic segmentation methods: a comparison of MAPER & FreeSurfer using three atlas databases by Yaakub, Siti Nurbaya, Heckemann, Rolf A., Keller, Simon S., McGinnity, Colm J., Weber, Bernd, Hammers, Alexander

“…Several automatic image segmentation methods and few atlas databases exist for analysing structural T1-weighted magnetic resonance brain images. The impact of…”
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Multi‐modal synergistic PET and MR reconstruction using mutually weighted quadratic priors by Mehranian, Abolfazl, Belzunce, Martin A., McGinnity, Colm J., Bustin, Aurelien, Prieto, Claudia, Hammers, Alexander, Reader, Andrew J.

“…Purpose To propose a framework for synergistic reconstruction of PET‐MR and multi‐contrast MR data to improve the image quality obtained from noisy PET data…”
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Intercomparison of MR‐informed PET image reconstruction methods by Bland, James, Mehranian, Abolfazl, Belzunce, Martin A., Ellis, Sam, Costa‐Luis, Casper, McGinnity, Colm J., Hammers, Alexander, Reader, Andrew J.

“…Purpose Numerous image reconstruction methodologies for positron emission tomography (PET) have been developed that incorporate magnetic resonance (MR) imaging…”
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Motion‐corrected and high‐resolution anatomically assisted (MOCHA) reconstruction of arterial spin labeling MRI by Mehranian, Abolfazl, McGinnity, Colm J., Neji, Radhouene, Prieto, Claudia, Hammers, Alexander, De Vita, Enrico, Reader, Andrew J.

“…Purpose A model‐based reconstruction framework is proposed for motion‐corrected and high‐resolution anatomically assisted (MOCHA) reconstruction of arterial…”
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A prospective 5-year longitudinal study detects neurocognitive and imaging correlates of seizure remission in self-limiting Rolandic epilepsy by Smith, Stuart D.W., McGinnity, Colm J., Smith, Anna B., Barker, Gareth J., Richardson, Mark P., Pal, Deb K.

“…•Altered brain development in left-frontal lobe structures in children with Rolandic epilepsy (RE).•During active epilepsy, developmental coordination disorder…”
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MR-Guided Kernel EM Reconstruction for Reduced Dose PET Imaging by Bland, James, Mehranian, Abolfazl, Belzunce, Martin A., Ellis, Sam, McGinnity, Colm J., Hammers, Alexander, Reader, Andrew J.

“…PET image reconstruction is highly susceptible to the impact of Poisson noise, and if shorter acquisition times or reduced injected doses are used, the noisy…”
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Test-retest reproducibility of quantitative binding measures of [11C]Ro15-4513, a PET ligand for GABAAreceptors containing alpha5 subunits by McGinnity, Colm J, Riaño Barros, Daniela A, Rosso, Lula, Veronese, Mattia, Rizzo, Gaia, Bertoldo, Alessandra, Hinz, Rainer, Turkheimer, Federico E, Koepp, Matthias J, Hammers, Alexander

“…Introduction Alteration of γ-aminobutyric acid “A” (GABAA) receptor-mediated neurotransmission has been associated with various neurological and psychiatric…”
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Deep Convolutional Backbone Comparison for Automated PET Image Quality Assessment by Hopson, Jessica B., Flaus, Anthime, McGinnity, Colm J., Neji, Radhouene, Reader, Andrew J., Hammers, Alexander

“…Pretraining deep convolutional network mappings using natural images helps with medical imaging analysis tasks; this is important given the limited number of…”
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The association between N-methyl-d-aspartate receptor availability and glutamate levels: A multi-modal PET-MR brain imaging study in first-episode psychosis and healthy controls by Beck, Katherine, Arumuham, Atheeshaan, Brugger, Stefan, McCutcheon, Robert A, Veronese, Mattia, Santangelo, Barbara, McGinnity, Colm J, Dunn, Joel, Kaar, Stephen, Singh, Nisha, Pillinger, Toby, Borgan, Faith, Sementa, Teresa, Neji, Radhouene, Jauhar, Sameer, Aigbirhio, Franklin, Boros, Istvan, Turkheimer, Federico, Hammers, Alexander, Lythgoe, David, Stone, James, Howes, Oliver D

“…Background: Evidence from post-mortem studies and in vivo imaging studies suggests there may be reduced N-methyl-d-aspartate receptor (NMDAR) levels in the…”
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Test-retest reproducibility of quantitative binding measures of [ 11 C]Ro15-4513, a PET ligand for GABA A receptors containing alpha5 subunits by McGinnity, Colm J, Riaño Barros, Daniela A, Rosso, Lula, Veronese, Mattia, Rizzo, Gaia, Bertoldo, Alessandra, Hinz, Rainer, Turkheimer, Federico E, Koepp, Matthias J, Hammers, Alexander

“…Alteration of γ-aminobutyric acid "A" (GABA ) receptor-mediated neurotransmission has been associated with various neurological and psychiatric disorders. […”
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Pre-Training, Transfer Learning and Pretext Learning for a Convolutional Neural Network Applied to Automated Assessment of Clinical PET Image Quality by Hopson, Jessica B., Neji, Radhouene, Dunn, Joel T., McGinnity, Colm J., Flaus, Anthime, Reader, Andrew J., Hammers, Alexander

“…Positron emission tomography (PET) using a fraction of the usual injected dose would reduce the amount of radioligand needed, as well as the radiation dose to…”
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Spatially Compact MR-Guided Kernel EM for PET Image Reconstruction by Bland, James, Belzunce, Martin A., Ellis, Sam, McGinnity, Colm J., Hammers, Alexander, Reader, Andrew J.

“…Positron emission tomography (PET) is a highly sensitive functional and molecular imaging modality which can measure picomolar concentrations of an injected…”
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