Search Results - "McGinnis, Ralph E."
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Insulin gene 5' flanking polymorphism : length of class 1 alleles in number of repeat units
Published in Diabetes (New York, N.Y.) (01-11-1995)“…The 5' flanking polymorphism (5'FP) is a minisatellite, variable number of tandem repeat (VNTR) locus adjacent to the 5' end of the insulin gene (INS). Alleles…”
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Visualizing Chromosome Mosaicism and Detecting Ethnic Outliers by the Method of “Rare” Heterozygotes and Homozygotes (RHH)
Published in Human molecular genetics (01-07-2010)“…We describe a novel approach for evaluating SNP genotypes of a genome-wide association scan to identify “ethnic outlier” subjects whose ethnicity is different…”
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Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland
Published in Nature genetics (01-06-2001)“…The NOTCH4 gene was recently reported to be associated with schizophrenia based on TDT analysis of 80 British trios. The strongest evidence for association…”
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Characterization of Common Genetic Variants in Cathepsin K and Testing for Association With Bone Mineral Density in a Large Cohort of Perimenopausal Women From Scotland
Published in Journal of bone and mineral research (01-01-2004)“…BMD values in ∼3000 perimenopausal Scottish women were adjusted by regression to identify and account for nongenetic factors. Adjusted BMD values were not…”
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The TDT reveals linkage and linkage disequilibrium in a rare disease
Published in Genetic epidemiology (1995)“…We used the TDT as the basis for our analysis of data from Problem 1 of GAW9. Among the 360 marker loci on six chromosomes, we searched for any that might show…”
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Insulin expression: is VNTR allele 698 really anomalous?
Published in Nature genetics (01-08-1995)“…Two recent papers in Nature Genetics report that insulin mRNA expression is correlated with the length of the polymorphic VNTR immediately 5' to the insulin…”
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Transmission test for linkage disequilibrium : the insulin gene region and insulin-dependent diabetes mellitus (IDDM)
Published in American journal of human genetics (01-03-1993)“…A population association has consistently been observed between insulin-dependent diabetes mellitus (IDDM) and the "class 1" alleles of the region of…”
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Linkage disequilibrium in the insulin gene region: size variation at the 5' flanking polymorphism and bimodality among "class I" alleles
Published in American journal of human genetics (01-09-1994)“…The 5' flanking polymorphism (5'FP), a hypervariable region at the 5' end of the insulin gene, has "class 1" alleles (650-900 bp long) that are in positive…”
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