Search Results - "McGinley, John N."

Dietary Oncopharmacognosy as a Crosswalk between Precision Oncology and Precision Nutrition by Thompson, Henry J, Lutsiv, Tymofiy, McGinley, John N, Hussan, Hisham, Playdon, Mary C

“…While diet and nutrition are modifiable risk factors for many chronic and infectious diseases, their role in cancer prevention and control remains under…”
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Consumption of Common Bean Suppresses the Obesogenic Increase in Adipose Depot Mass: Impact of Dose and Biological Sex by Thompson, Henry J, Lutsiv, Tymofiy, McGinley, John N, Fitzgerald, Vanessa K, Neil, Elizabeth S

“…Obesity prevention is stated as a simple objective in the public health guidelines of most countries: avoid adult weight gain. However, the success of the…”
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Thwarting Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) with Common Bean: Dose- and Sex-Dependent Protection against Hepatic Steatosis by Lutsiv, Tymofiy, McGinley, John N, Neil, Elizabeth S, Foster, Michelle T, Thompson, Henry J

“…Hepatic steatosis signifies onset of metabolic dysfunction-associated fatty liver disease (MAFLD) caused by disrupted metabolic homeostasis compromising liver…”
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Compositional Changes of the High-Fat Diet-Induced Gut Microbiota upon Consumption of Common Pulses by Lutsiv, Tymofiy, Weir, Tiffany L, McGinley, John N, Neil, Elizabeth S, Wei, Yuren, Thompson, Henry J

“…The gut microbiome is involved in the host's metabolism, development, and immunity, which translates to measurable impacts on disease risk and overall health…”
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Common Bean Suppresses Hepatic Ceramide Metabolism in a Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease by Fitzgerald, Vanessa K, Lutsiv, Tymofiy, McGinley, John N, Neil, Elizabeth S, Playdon, Mary C, Thompson, Henry J

“…The incidence of metabolic dysfunction-associated steatotic liver disease (MASLD), a condition linked to the ongoing obesity pandemic, is rapidly increasing…”
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Impact of a Pulse-Enriched Human Cuisine on Functional Attributes of the Gut Microbiome Using a Preclinical Model of Dietary-Induced Chronic Diseases by Lutsiv, Tymofiy, Neil, Elizabeth S, McGinley, John N, Didinger, Chelsea, Fitzgerald, Vanessa K, Weir, Tiffany L, Hussan, Hisham, Hartman, Terryl J, Thompson, Henry J

“…Introducing grain legumes, i.e., pulses, into any food pattern effectively increases dietary fiber and other bioactive food components of public health…”
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White Kidney Bean ( Phaseolus Vulgaris L.) Consumption Reduces Fat Accumulation in a Polygenic Mouse Model of Obesity by Neil, Elizabeth S, McGinley, John N, Fitzgerald, Vanessa K, Lauck, Corey A, Tabke, Jeremy A, Streeter-McDonald, Madyson R, Yao, Linxing, Broeckling, Corey D, Weir, Tiffany L, Foster, Michelle T, Thompson, Henry J

“…Clinical studies indicate that eating common bean, L., plays a role in body weight regulation but mechanisms have yet to be elucidated. Here, we investigated…”
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Measuring Dietary Botanical Diversity as a Proxy for Phytochemical Exposure by Thompson, Henry J, Levitt, Jack O, McGinley, John N, Chandler, Paulette, Guenther, Patricia M, Huybrechts, Inge, Playdon, Mary C

“…The study of natural plant molecules and their medicinal properties, pharmacognosy, provides a taxonomy for botanical families that represent diverse chemical…”
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Beneficial Effects of Common Bean on Adiposity and Lipid Metabolism by Thompson, Henry J, McGinley, John N, Neil, Elizabeth S, Brick, Mark A

“…In developed countries which are at the epicenter of the obesity pandemic, pulse crop consumption is well below recommended levels. In a recent systematic…”
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Cell Signaling Pathways in Mammary Carcinoma Induced in Rats with Low versus High Inherent Aerobic Capacity by Lutsiv, Tymofiy, McGinley, John N, Neil, Elizabeth S, Thompson, Henry J

“…An inverse association exists between physical activity and breast cancer incidence and outcomes. An objective indicator of an individual's recent physical…”
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Pre-Clinical Insights into the Iron and Breast Cancer Hypothesis by Thompson, Henry J., Neil, Elizabeth S., McGinley, John N.

“…Population studies, systematic reviews, and meta-analyses have revealed no relationship between iron status and breast cancer, a weak positive association, or…”
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Pulse Crop Effects on Gut Microbial Populations, Intestinal Function, and Adiposity in a Mouse Model of Diet-Induced Obesity by McGinley, John N, Fitzgerald, Vanessa K, Neil, Elizabeth S, Omerigic, Heather M, Heuberger, Adam L, Weir, Tiffany L, McGee, Rebecca, Vandemark, George, Thompson, Henry J

“…The dietary fiber gap that is present in many countries co-exists with a low intake of grain legumes (pulses) that have 2-3 times more dietary fiber than…”
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A Randomized, Double-Blind, Placebo-Controlled Investigation of Selenium Supplementation in Women at Elevated Risk for Breast Cancer: Lessons for Re-Emergent Interest in Selenium and Cancer by Thompson, Henry J, Sedlacek, Scot M, Fitzgerald, Vanessa K, Wolfe, Pamela, McGinley, John N

“…Damage to cellular macromolecules such as DNA and lipid, induced via reactive oxygen species, and indicators of cell proliferation potential such as…”
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Relandscaping the Gut Microbiota with a Whole Food: Dose-Response Effects to Common Bean by Lutsiv, Tymofiy, McGinley, John N, Neil-McDonald, Elizabeth S, Weir, Tiffany L, Foster, Michelle T, Thompson, Henry J

“…Underconsumption of dietary fiber and the milieu of chemicals with which it is associated is a health concern linked to the increasing global burden of chronic…”
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Weight loss interventions for breast cancer survivors: impact of dietary pattern by Thompson, Henry J, Sedlacek, Scot M, Playdon, Mary C, Wolfe, Pamela, McGinley, John N, Paul, Devchand, Lakoski, Susan G

“…Body weight management is not emphasized in clinical practice guidelines for breast cancer survivors, reflecting the lack of evidence that weight loss improves…”
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Impact of Weight Loss on Plasma Leptin and Adiponectin in Overweight-to-Obese Post Menopausal Breast Cancer Survivors by Thompson, Henry J, Sedlacek, Scot M, Wolfe, Pamela, Paul, Devchand, Lakoski, Susan G, Playdon, Mary C, McGinley, John N, Matthews, Shawna B

“…Women who are obese at the time of breast cancer diagnosis have higher overall mortality than normal weight women and some evidence implicates adiponectin and…”
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Effect of Nonmotorized Wheel Running on Mammary Carcinogenesis: Circulating Biomarkers, Cellular Processes, and Molecular Mechanisms in Rats by ZONGJIAN ZHU, WEIQIN JIANG, SELLS, Jennifer L, NEIL, Elizabeth S, MCGINLEY, John N, THOMPSON, Henry J

“…The objective of this experiment was to identify circulating growth factors, hormones, and cellular and molecular mechanisms that account for the effects of…”
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Premenopausal Obesity and Breast Cancer Growth Rates in a Rodent Model by Matthews, Shawna B, McGinley, John N, Neil, Elizabeth S, Thompson, Henry J

“…Obese premenopausal women with breast cancer have poorer prognosis for long term survival, in part because their tumors are larger at the time of diagnosis…”
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Quantitative assessment of mammary gland density in rodents using digital image analysis by McGinley, John N, Thompson, Henry J

“…Rodent models have been used extensively to study mammary gland development and for studies of toxicology and carcinogenesis. Mammary gland gross morphology…”
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Effect of a low fat versus a low carbohydrate weight loss dietary intervention on biomarkers of long term survival in breast cancer patients ('CHOICE'): study protocol by Sedlacek, Scot M, Playdon, Mary C, Wolfe, Pamela, McGinley, John N, Wisthoff, Mark R, Daeninck, Elizabeth A, Jiang, Weiqin, Zhu, Zongjian, Thompson, Henry J

“…Weight loss in overweight or obese breast cancer patients is associated with an improved prognosis for long term survival. However, it is not clear whether the…”
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