Search Results - "McGill, Jodi L"
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Aerosol vaccination with Bacille Calmette-Guerin induces a trained innate immune phenotype in calves
Published in PloS one (22-02-2019)“…Mycobacterium bovis Bacillus Calmette-Guérin (BCG) is a live attenuated vaccine for use against tuberculosis (TB); however, it is known to reduce childhood…”
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Innate Immunomodulation in Food Animals: Evidence for Trained Immunity?
Published in Frontiers in immunology (05-06-2020)“…Antimicrobial resistance (AMR) is a significant problem in health care, animal health, and food safety. To limit AMR, there is a need for alternatives to…”
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3
Supplementing a Saccharomyces cerevisiae fermentation product modulates innate immune function and ameliorates bovine respiratory syncytial virus infection in neonatal calves
Published in Journal of animal science (01-08-2020)“…Abstract The objectives of this study were to determine the effects of oral supplementation with Saccharomyces cerevisiae fermentation products (SCFP;…”
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4
Vitamin A deficiency impairs the immune response to intranasal vaccination and RSV infection in neonatal calves
Published in Scientific reports (22-10-2019)“…Respiratory syncytial virus (RSV) infection is a leading cause of severe acute lower respiratory tract infection in infants and children worldwide. Vitamin A…”
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Development of surface engineered antigenic exosomes as vaccines for respiratory syncytial virus
Published in Scientific reports (01-11-2021)“…Respiratory syncytial virus (RSV) is one of the main pathogens associated with lower respiratory tract infections in infants and young children worldwide…”
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6
Feeding Saccharomyces cerevisiae fermentation postbiotic products alters immune function and the lung transcriptome of preweaning calves with an experimental viral-bacterial coinfection
Published in Journal of dairy science (01-04-2024)“…Bovine respiratory disease causes morbidity and mortality in cattle of all ages. Supplementing with postbiotic products from Saccharomyces cerevisiae…”
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Efficacy of mucosal polyanhydride nanovaccine against respiratory syncytial virus infection in the neonatal calf
Published in Scientific reports (14-02-2018)“…Human respiratory syncytial virus (HRSV) is a leading cause of severe acute lower respiratory tract infection in infants and children worldwide. Bovine RSV…”
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8
Prophylactic digoxin treatment reduces IL-17 production in vivo in the neonatal calf and moderates RSV-associated disease
Published in PloS one (25-03-2019)“…Respiratory syncytial virus (RSV) is a leading cause of morbidity and mortality in human infants. Bovine RSV infection of neonatal calves is pathologically and…”
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Bovine Gamma Delta T Cells Contribute to Exacerbated IL-17 Production in Response to Co-Infection with Bovine RSV and Mannheimia haemolytica
Published in PloS one (04-03-2016)“…Human respiratory syncytial virus (HRSV) is a leading cause of severe lower respiratory tract infection in children under five years of age. IL-17 and Th17…”
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10
Evidence of innate training in bovine γδ T cells following subcutaneous BCG administration
Published in Frontiers in immunology (18-07-2024)“…The Bacillus Calmette Guerin (BCG) vaccine has been shown to induce non-specific protection against diseases other than tuberculosis in vaccinated individuals,…”
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11
A Recombinant BCG Vaccine Is Safe and Immunogenic in Neonatal Calves and Reduces the Clinical Disease Caused by the Respiratory Syncytial Virus
Published in Frontiers in immunology (26-04-2021)“…The human respiratory syncytial virus (hRSV) constitutes a major health burden, causing millions of hospitalizations in children under five years old worldwide…”
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12
Current Animal Models for Understanding the Pathology Caused by the Respiratory Syncytial Virus
Published in Frontiers in microbiology (03-05-2019)“…The human respiratory syncytial virus (hRSV) is the main etiologic agent of severe lower respiratory tract infections that affect young children throughout the…”
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13
Immunization with a mucosal, post-fusion F/G protein-based polyanhydride nanovaccine protects neonatal calves against BRSV infection
Published in Frontiers in immunology (09-06-2023)“…Human respiratory syncytial virus (HRSV) is a leading cause of death in young children and there are no FDA approved vaccines. Bovine RSV (BRSV) is…”
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14
Parainfluenza Virus 3 Blocks Antiviral Mediators Downstream of the Interferon Lambda Receptor by Modulating Stat1 Phosphorylation
Published in Journal of virology (15-03-2016)“…Parainfluenza viruses are known to inhibit type I interferon (IFN) production; however, there is a lack of information regarding the type III IFN response…”
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15
Identification of a DRB3011:01-restricted CD4 + T cell response against bovine respiratory syncytial virus fusion protein
Published in Frontiers in immunology (20-02-2023)“…Although Human Respiratory Syncytial Virus (HRSV) is a significant cause of severe respiratory disease with high morbidity and mortality in pediatric and…”
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16
Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4+ T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host
Published in PloS one (03-02-2016)“…Ehrlichia chaffeensis is a tick-borne rickettsial pathogen and the causative agent of human monocytic ehrlichiosis. Transmitted by the Amblyomma americanum…”
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17
Applications of Nanovaccines for Disease Prevention in Cattle
Published in Frontiers in bioengineering and biotechnology (11-12-2020)“…Vaccines are one of the most important tools available to prevent and reduce the incidence of infectious diseases in cattle. Despite their availability and…”
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18
Increased TNF-α/IFN-γ/IL-2 and Decreased TNF-α/IFN-γ Production by Central Memory T Cells Are Associated with Protective Responses against Bovine Tuberculosis Following BCG Vaccination
Published in Frontiers in immunology (17-10-2016)“…Central memory T cell (Tcm) and polyfunctional CD4 T cell responses contribute to vaccine-elicited protection with both human and bovine tuberculosis (TB);…”
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The Effects of Ursolic Acid Treatment on Immunopathogenesis Following Mannheimia haemolytica Infections
Published in Frontiers in veterinary science (18-11-2021)“…Bovine respiratory disease complex (BRDC) is a costly economic and health burden for the dairy and feedlot cattle industries. BRDC is a multifactorial disease,…”
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Antigen-Specific CD4 + CD8 + Double-Positive T Cells Are Increased in the Blood and Spleen During Ehrlichia chaffeensis Infection in the Canine Host
Published in Frontiers in immunology (11-07-2018)“…is an obligate intracellular bacterium belonging to the order, Rickettsiales and is a frequent cause of severe and fatal tick-borne infection in people in…”
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