Search Results - "McGee, Sean"

Exercise adaptations: molecular mechanisms and potential targets for therapeutic benefit by McGee, Sean L., Hargreaves, Mark

“…Exercise is fundamental for good health, whereas physical inactivity underpins many chronic diseases of modern society. It is well appreciated that regular…”
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Epigenetics and Exercise by McGee, Sean L., Hargreaves, Mark

“…Epigenetics can be defined as ‘the structural adaptation of chromosomal regions so as to register, signal, or perpetuate altered activity states.’ Increased…”
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Exercise performance and health: Role of GLUT4 by McGee, Sean L., Hargreaves, Mark

“…The glucose transporter GLUT4 is integral for optimal skeletal muscle performance during exercise, as well as for metabolic health. Physiological regulation of…”
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Metallicity beats sSFR: the connection between superluminous supernova host galaxy environments and the importance of metallicity for their production by Cleland, Cressida, McGee, Sean L, Nicholl, Matt

“…ABSTRACT We analyse 33 Type I superluminous supernovae (SLSNe) taken from Zwicky Transient Facility (ZTF)’s Bright Transient Survey to investigate the local…”
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Exercise and GLUT4 by Flores-Opazo, Marcelo, McGee, Sean L., Hargreaves, Mark

“…The glucose transporter GLUT4 is critical for skeletal muscle glucose uptake in response to insulin and muscle contraction/exercise. Exercise increases GLUT4…”
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The environmental dependence of rapidly quenching and rejuvenating galaxies by Cleland, Cressida, McGee, Sean L

“…ABSTRACT By combining H α flux measurements from the Sloan Digital Sky Survey (SDSS) with ultraviolet (UV) flux observations from the Galaxy Evolution Explorer…”
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The bulge masses of TDE host galaxies and their scaling with black hole mass by Ramsden, Paige, Lanning, Daniel, Nicholl, Matt, McGee, Sean L

“…ABSTRACT Tidal disruption events (TDEs) provide a means to probe the low end of the supermassive black hole (SMBH) mass distribution, as they are only…”
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Photometric variability in star-forming galaxies as evidence for low-mass AGN and a precursor to quenching by Cleland, Cressida, McGee, Sean L

“…ABSTRACT We measure the optical variability in ∼16 500 low-redshift (z ∼ 0.1) galaxies to map the relations between active galactic nucleus (AGN) activity and…”
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AMPK-mediated regulation of transcription in skeletal muscle by McGee, Sean L, Hargreaves, Mark

“…Skeletal muscle phenotype plays a critical role in human performance and health, and skeletal muscle oxidative capacity is a key determinant of exercise…”
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A model of the mitochondrial basis of bipolar disorder by Morris, Gerwyn, Walder, Ken, McGee, Sean L., Dean, Olivia M., Tye, Susannah J., Maes, Michael, Berk, Michael

“…•Bipolar disorder phenomenologically is a biphasic disorder of energy; increased in mania and decreased in depression.•There is evidence of increased…”
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Exercise-induced histone modifications in human skeletal muscle by McGee, Sean L., Fairlie, Erin, Garnham, Andrew P., Hargreaves, Mark

“…Skeletal muscle adaptations to exercise confer many of the health benefits of physical activity and occur partly through alterations in skeletal muscle gene…”
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The role of mitochondria in the aetiology of insulin resistance and type 2 diabetes by Martin, Sheree D., McGee, Sean L.

“…The prevalence of type 2 diabetes is rapidly increasing world-wide and insulin resistance is central to the aetiology of this disease. The biology underpinning…”
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GASP. IX. Jellyfish galaxies in phase-space: an orbital study of intense ram-pressure stripping in clusters by Jaffé, Yara L, Poggianti, Bianca M, Moretti, Alessia, Gullieuszik, Marco, Smith, Rory, Vulcani, Benedetta, Fasano, Giovanni, Fritz, Jacopo, Tonnesen, Stephanie, Bettoni, Daniela, Hau, George, Biviano, Andrea, Bellhouse, Callum, McGee, Sean

“…Abstract It is well known that galaxies falling into clusters can experience gas stripping due to ram pressure by the intra-cluster medium. The most…”
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The role of protein kinase D (PKD) in obesity: Lessons from the heart and other tissues by Renton, Mark C., McGee, Sean L., Howlett, Kirsten F.

“…Obesity causes a range of tissue dysfunctions that increases the risk for morbidity and mortality. Protein kinase D (PKD) represents a family of…”
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Metabolic reprogramming in type 2 diabetes and the development of breast cancer by Martin, Sheree D, McGee, Sean L

“…A wealth of epidemiological data has found that patients with type 2 diabetes have a greater risk of developing breast cancer. The molecular mechanisms…”
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GASP. XXI. Star Formation Rates in the Tails of Galaxies Undergoing Ram Pressure Stripping by Gullieuszik, Marco, Poggianti, Bianca M., McGee, Sean L., Moretti, Alessia, Vulcani, Benedetta, Tonnesen, Stephanie, Roediger, Elke, Jaffé, Yara L., Fritz, Jacopo, Franchetto, Andrea, Omizzolo, Alessandro, Bettoni, Daniela, Radovich, Mario, Wolter, Anna

“…Using MUSE observations from the GASP survey, we study 54 galaxies undergoing ram pressure stripping (RPS) and spanning a wide range in galaxy mass and host…”
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Polycystic ovarian syndrome increases prevalence of concentric hypertrophy in normotensive obese women by De Jong, Kirstie A, Berisha, Filip, Naderpoor, Negar, Appelbe, Alan, Kotowicz, Mark A, Cukier, Kimberly, McGee, Sean L, Nikolaev, Viacheslav O

“…It remains unclear as to whether polycystic ovary syndrome (PCOS) is an additional risk factor in the development of left ventricular (LV) hypertrophy in obese…”
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Histone modifications and exercise adaptations by MCGEE, Sean L, HARGREAVES, Mark

“…The spatial association between genomic DNA and histone proteins within chromatin plays a key role in the regulation of gene expression and is largely governed…”
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3T3-L1 adipocytes display phenotypic characteristics of multiple adipocyte lineages by Morrison, Shona, McGee, Sean L

“…Differentiated 3T3-L1 adipocytes are a widely used in vitro model of white adipocytes. In addition to classical white and brown adipocytes that are derived…”
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The role of protein kinase D (PKD) in intracellular nutrient sensing and regulation of adaptive responses to the obese environment by Renton, Mark C., McGee, Sean L., Howlett, Kirsten F.

“…Summary Obesity is associated with ectopic accumulation of lipids, which is implicated in the development of insulin resistance, type 2 diabetes mellitus and…”
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