Search Results - "McGee, Ryan"

The Pharmacokinetics, Pharmacodynamics, and Safety of Orally Dosed INCB018424 Phosphate in Healthy Volunteers by Shi, Jack G., Chen, Xuejun, McGee, Ryan F., Landman, Robert R., Emm, Thomas, Lo, Yvonne, Scherle, Peggy A., Punwani, Naresh G., Williams, William V., Yeleswaram, Swamy

“…INCB018424 phosphate, a potent inhibitor of JAK enzymes with selectivity for JAK1&2, is in development for the treatment of myelofibrosis (MF). The oral dose…”
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Effect of process parameters on phase stability and metal-insulator transition of vanadium dioxide (VO2) thin films by pulsed laser deposition by McGee, Ryan, Goswami, Ankur, Khorshidi, Behnam, McGuire, Kristi, Schofield, Kalvin, Thundat, Thomas

“…Owing to remarkable thermochromic, electrochromic, and photochromic properties which arise from a first-order phase transition from insulator to metal at…”
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Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050 by Fridman, Jordan S, Scherle, Peggy A, Collins, Robert, Burn, Timothy C, Li, Yanlong, Li, Jun, Covington, Maryanne B, Thomas, Beth, Collier, Paul, Favata, Margaret F, Wen, Xiaoming, Shi, Jack, McGee, Ryan, Haley, Patrick J, Shepard, Stacey, Rodgers, James D, Yeleswaram, Swamy, Hollis, Greg, Newton, Robert C, Metcalf, Brian, Friedman, Steven M, Vaddi, Kris

“…Inhibiting signal transduction induced by inflammatory cytokines offers a new approach for the treatment of autoimmune diseases such as rheumatoid arthritis…”
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Effect of interface on mid-infrared photothermal response of MoS2 thin film grown by pulsed laser deposition by Goswami, Ankur, Dhandaria, Priyesh, Pal, Soupitak, McGee, Ryan, Khan, Faheem, Antić, Željka, Gaikwad, Ravi, Prashanthi, Kovur, Thundat, Thomas

“…This study reports on the mid-infrared （mid-IR） photothermal response of multilayer MoS2 thin films grown on crystalline （p-type silicon and c-axis- oriented…”
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The Effect of CYP3A4 Inhibition or Induction on the Pharmacokinetics and Pharmacodynamics of Orally Administered Ruxolitinib (INCB018424 Phosphate) in Healthy Volunteers by Shi, Jack G., Chen, Xuejun, Emm, Thomas, Scherle, Peggy A., McGee, Ryan F., Lo, Yvonne, Landman, Robert R., McKeever Jr, Edward G., Punwani, Naresh G., Williams, William V., Yeleswaram, Swamy

“…Ruxolitinib, a selective Janus kinase (JAK) 1&2 inhibitor in development for the treatment of myeloproliferative neoplasms, is primarily metabolized by CYP3A4…”
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Model-driven mitigation measures for reopening schools during the COVID-19 pandemic by McGee, Ryan Seamus, Homburger, Julian R., Williams, Hannah E., Bergstrom, Carl T., Zhou, Alicia Y.

“…Reopening schools is an urgent priority as the COVID-19 pandemic drags on. To explore the risks associated with returning to in-person learning and the value…”
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In-situ probing of thermal desorption of vapor molecules on a nanowire via work function variance by Prashanthi, Kovur, Hawk, John Eric, McGee, Ryan, Gaikwad, Ravi, Thundat, Thomas

“…Nanowire sensors based on variations of their electrical properties show great potential for real-time, in situ monitoring of molecular adsorption and…”
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Pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in renal and hepatic impairment patients by Chen, Xuejun, Shi, Jack G., Emm, Thomas, Scherle, Peggy A., McGee, Ryan F., Lo, Yvonne, Landman, Robert R., Punwani, Naresh G., Williams, William V., Yeleswaram, Swamy

“…Hepatic and renal impairment studies were conducted with ruxolitinib, a JAK1&2 inhibitor that is cleared predominantly by metabolism. Both studies were open…”
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Quantifying over expression of FoxP2 in the brain of budgerigars using immunohistochemistry by McGee, Ryan Michelle

“…Abstract only The gene FoxP2 is believed to have a significant role in the vocal circuit pathway in humans and other vocal learning taxa. We wanted to…”
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Direct-current triboelectricity generation by a sliding Schottky nanocontact on MoS2 multilayers by Liu, Jun, Goswami, Ankur, Jiang, Keren, Khan, Faheem, Kim, Seokbeom, McGee, Ryan, Li, Zhi, Hu, Zhiyu, Lee, Jungchul, Thundat, Thomas

“…The direct conversion of mechanical energy into electricity by nanomaterial-based devices offers potential for green energy harvesting 1 – 3 . A conventional…”
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Control System Development for the Dual Drive Hybrid System by Phillips, Anthony M, McGee, Ryan A, Lockwood, J. Tony, Spiteri, Ray A, Che, Judy, Blankenship, John R, Kuang, Ming L

“…Automotive manufacturers continue to move further toward powertrain electrification. There are already many hybrid electric vehicles on the market that are…”
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Improving the Accuracy of Bulk Fitness Assays by Correcting Barcode Processing Biases by McGee, Ryan Seamus, Kinsler, Grant, Petrov, Dmitri, Tikhonov, Mikhail

“…Abstract Measuring the fitnesses of genetic variants is a fundamental objective in evolutionary biology. A standard approach for measuring microbial fitnesses…”
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Trip-Oriented Energy Management Control Strategy for Plug-In Hybrid Electric Vehicles by Hai Yu, Ming Kuang, McGee, Ryan

“…This paper presents a trip-oriented energy management control strategy for plug-in hybrid electric vehicle (PHEV). The proposed strategy provides system…”
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Bioanalysis of INCB000928 in hemodialysate: prevention of nonspecific binding and validation of surrogate matrices by Xun, Zhiyin, Wang, Phillip, McGee, Ryan

“…To develop and validate a bioanalytical method for the quantification of INCB000928 in hemodialysate. Blank dialysate and phosphate-buffered saline were…”
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Pharmacokinetics of Ruxolitinib in Patients with Atopic Dermatitis Treated With Ruxolitinib Cream: Data from Phase II and III Studies by Gong, Xiaohua, Chen, Xuejun, Kuligowski, Michael E., Liu, Xing, Liu, Xiang, Cimino, Evan, McGee, Ryan, Yeleswaram, Swamy

“…Background Pathogenesis of atopic dermatitis (AD) involves the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway. A cream…”
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Sustained electron tunneling at unbiased metal-insulator-semiconductor triboelectric contacts by Liu, Jun, Miao, Mengmeng, Jiang, Keren, Khan, Faheem, Goswami, Ankur, McGee, Ryan, Li, Zhi, Nguyen, Lan, Hu, Zhiyu, Lee, Jungchul, Cadien, Ken, Thundat, Thomas

“…Generating sufficient current density for powering electronic devices remains as one of the critical challenges of mechanical energy harvesting techniques…”
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Evolutionary “Crowdsourcing”: Alignment of Fitness Landscapes Allows for Cross-species Adaptation of a Horizontally Transferred Gene by Kosterlitz, Olivia, Grassi, Nathan, Werner, Bailey, McGee, Ryan Seamus, Top, Eva M, Kerr, Benjamin

“…Abstract Genes that undergo horizontal gene transfer (HGT) evolve in different genomic backgrounds. Despite the ubiquity of cross-species HGT, the effects of…”
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Itacitinib Population Pharmacokinetics and Exposure‐Response in Patients With Acute Graft‐Versus‐Host Disease by Chen, Xuejun, Xun, Zhiyin, Yuska, Brad, McGee, Ryan, Yeleswaram, Swamy

“…This article presents the population pharmacokinetic (PopPK) analysis and exposure‐response analyses for the primary efficacy end point—acute graft‐versus‐host…”
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Adaptive Fuzzy Prediction for Automotive Applications Usage by Shiqi Qiu, McGee, Ryan A., Murphey, Yi L.

“…Modern automobiles are increasingly complicated machines with an ever-increasing number of features. Understanding how these features work, when to use them,…”
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An Energy Management Controller to Optimally Trade Off Fuel Economy and Drivability for Hybrid Vehicles by Opila, Daniel F., Wang, Xiaoyong, McGee, Ryan, Gillespie, R. Brent, Cook, Jeffrey A., Grizzle, Jessy W.

“…Hybrid vehicle fuel economy performance is highly sensitive to the energy management strategy used to regulate power flow among the various energy sources and…”
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