Search Results - "McGaugh, Suzanne"

Quantitative trait loci concentrate in specific regions of the Mexican cavefish genome and reveal key candidate genes for cave-associated evolution by Wiese, Jonathan, Richards, Emilie, Kowalko, Johanna E, McGaugh, Suzanne E

“…A major goal of modern biology is connecting phenotype with its underlying genetic basis. The Mexican cavefish (Astyanax mexicanus), a characin fish species…”
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It’s time to stop sweeping recombination rate under the genome scan rug by Stevison, Laurie S., McGaugh, Suzanne E.

“…Different parts of the genome can vary widely in their evolutionary histories and sequence divergence from other species. Indeed, some of the most interesting…”
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Repeated evolution of circadian clock dysregulation in cavefish populations by Mack, Katya L, Jaggard, James B, Persons, Jenna L, Roback, Emma Y, Passow, Courtney N, Stanhope, Bethany A, Ferrufino, Estephany, Tsuchiya, Dai, Smith, Sarah E, Slaughter, Brian D, Kowalko, Johanna, Rohner, Nicolas, Keene, Alex C, McGaugh, Suzanne E

“…Circadian rhythms are nearly ubiquitous throughout nature, suggesting they are critical for survival in diverse environments. Organisms inhabiting largely…”
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The utility of genomic prediction models in evolutionary genetics by McGaugh, Suzanne E., Lorenz, Aaron J., Flagel, Lex E.

“…Variation in complex traits is the result of contributions from many loci of small effect. Based on this principle, genomic prediction methods are used to make…”
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Widespread convergent evolution of alpha-neurotoxin resistance in African mammals by Drabeck, Danielle H, Holt, Jennifer, McGaugh, Suzanne E

“…Convergent evolution is central to the study of adaptation and has been used to understand both the limits of evolution and the diverse patterns and processes…”
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Selection-driven trait loss in independently evolved cavefish populations by Moran, Rachel L., Richards, Emilie J., Ornelas-García, Claudia Patricia, Gross, Joshua B., Donny, Alexandra, Wiese, Jonathan, Keene, Alex C., Kowalko, Johanna E., Rohner, Nicolas, McGaugh, Suzanne E.

“…Laboratory studies have demonstrated that a single phenotype can be produced by many different genotypes; however, in natural systems, it is frequently found…”
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The role of gene flow in rapid and repeated evolution of cave‐related traits in Mexican tetra, Astyanax mexicanus by Herman, Adam, Brandvain, Yaniv, Weagley, James, Jeffery, William R., Keene, Alex C., Kono, Thomas J. Y., Bilandžija, Helena, Borowsky, Richard, Espinasa, Luis, O'Quin, Kelly, Ornelas‐García, Claudia P., Yoshizawa, Masato, Carlson, Brian, Maldonado, Ernesto, Gross, Joshua B., Cartwright, Reed A., Rohner, Nicolas, Warren, Wesley C., McGaugh, Suzanne E.

“…Understanding the molecular basis of repeatedly evolved phenotypes can yield key insights into the evolutionary process. Quantifying gene flow between…”
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The cavefish genome reveals candidate genes for eye loss by McGaugh, Suzanne E., Gross, Joshua B., Aken, Bronwen, Blin, Maryline, Borowsky, Richard, Chalopin, Domitille, Hinaux, Hélène, Jeffery, William R., Keene, Alex, Ma, Li, Minx, Patrick, Murphy, Daniel, O’Quin, Kelly E., Rétaux, Sylvie, Rohner, Nicolas, Searle, Steve M. J., Stahl, Bethany A., Tabin, Cliff, Volff, Jean-Nicolas, Yoshizawa, Masato, Warren, Wesley C.

“…Natural populations subjected to strong environmental selection pressures offer a window into the genetic underpinnings of evolutionary change. Cavefish…”
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Recombination modulates how selection affects linked sites in Drosophila by McGaugh, Suzanne E, Heil, Caiti S S, Manzano-Winkler, Brenda, Loewe, Laurence, Goldstein, Steve, Himmel, Tiffany L, Noor, Mohamed A F

“…One of the most influential observations in molecular evolution has been a strong association between local recombination rate and nucleotide polymorphisms…”
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Pleiotropic function of the oca2 gene underlies the evolution of sleep loss and albinism in cavefish by O’Gorman, Morgan, Thakur, Sunishka, Imrie, Gillian, Moran, Rachel L., Choy, Stefan, Sifuentes-Romero, Itzel, Bilandžija, Helena, Renner, Kenneth J., Duboué, Erik, Rohner, Nicolas, McGaugh, Suzanne E., Keene, Alex C., Kowalko, Johanna E.

“…Adaptation to novel environments often involves the evolution of multiple morphological, physiological, and behavioral traits. One striking example of…”
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Assessing genomic and ecological differentiation among subspecies of the rough-footed mud turtle, Kinosternon hirtipes by Weaver, Sam, McGaugh, Suzanne E, Kono, Thomas J Y, Macip-Rios, Rodrigo, Gluesenkamp, Andrew G

“…Abstract Combining genetic and ecological measures of differentiation can provide compelling evidence for ecological and genetic divergence among lineages. The…”
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Scientist Spotlights: Online assignments to promote inclusion in Ecology and Evolution by Brandt, Samantha, Cotner, Sehoya, Koth, Zoe, McGaugh, Suzanne

“…Scientific disciplines face large diversity challenges, with the fields of ecology and evolution being among the most homogeneous—specifically with respect to…”
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Genomic impacts of chromosomal inversions in parapatric Drosophila species by McGaugh, Suzanne E., Noor, Mohamed A. F.

“…Chromosomal inversions impact genetic variation and facilitate speciation in part by reducing recombination in heterokaryotypes. We generated multiple…”
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CaveCrawler: An interactive analysis suite for cavefish bioinformatics by Perry, Annabel, McGaugh, Suzanne E, Keene, Alex C, Blackmon, Heath

“…The growing use of genomics in diverse organisms provides the basis for identifying genomic and transcriptional differences across species and experimental…”
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The limited role of differential fractionation in genome content variation and function in maize (Zea mays L.) inbred lines by Brohammer, Alex B., Kono, Thomas J. Y., Springer, Nathan M., McGaugh, Suzanne E., Hirsch, Candice N.

“…Summary Maize is a diverse paleotetraploid species with considerable presence/absence variation and copy number variation. One mechanism through which…”
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Gene loss and relaxed selection of plaat1 in vertebrates adapted to low-light environments by Drabeck, Danielle H, Wiese, Jonathan, Gilbertson, Erin, Arroyave, Jairo, Stiassny, Melanie L J, Alter, S Elizabeth, Borowsky, Richard, Hendrickson, Dean A, Arcila, Dahiana, McGaugh, Suzanne E

“…Gene loss is an important mechanism for evolution in low-light or cave environments where visual adaptations often involve a reduction or loss of eyesight. The…”
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Stable transgenesis in Astyanax mexicanus using the Tol2 transposase system by Stahl, Bethany A., Peuß, Robert, McDole, Brittnee, Kenzior, Alexander, Jaggard, James B., Gaudenz, Karin, Krishnan, Jaya, McGaugh, Suzanne E., Duboue, Erik R., Keene, Alex C., Rohner, Nicolas

“…Background Astyanax mexicanus is a well‐established fish model system for evolutionary and developmental biology research. These fish exist as surface forms…”
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Nonrandom RNAseq gene expression associated with RNAlater and flash freezing storage methods by Passow, Courtney N., Kono, Thomas J. Y., Stahl, Bethany A., Jaggard, James B., Keene, Alex C., McGaugh, Suzanne E.

“…RNA sequencing is a popular next‐generation sequencing technique for assaying genome‐wide gene expression profiles. Nonetheless, it is susceptible to biases…”
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Rapid molecular evolution across amniotes of the IIS/TOR network by McGaugh, Suzanne E., Bronikowski, Anne M., Kuo, Chih-Horng, Reding, Dawn M., Addis, Elizabeth A., Flagel, Lex E., Janzen, Fredric J., Schwartz, Tonia S.

“…Significance Comparative analyses of central molecular networks uncover variation that can be targeted by biomedical research to develop insights and…”
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How hot are drosophila hotspots? examining recombination rate variation and associations with nucleotide diversity, divergence, and maternal age in Drosophila pseudoobscura by Manzano-Winkler, Brenda, McGaugh, Suzanne E, Noor, Mohamed A F

“…Fine scale meiotic recombination maps have uncovered a large amount of variation in crossover rate across the genomes of many species, and such variation in…”
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