Search Results - "McFarland, Henry F."

Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria" by Polman, Chris H., Reingold, Stephen C., Edan, Gilles, Filippi, Massimo, Hartung, Hans-Peter, Kappos, Ludwig, Lublin, Fred D., Metz, Luanne M., McFarland, Henry F., O'Connor, Paul W., Sandberg-Wollheim, Magnhild, Thompson, Alan J., Weinshenker, Brian G., Wolinsky, Jerry S.

“…New diagnostic criteria for multiple sclerosis integrating magnetic resonance image assessment with clinical and other paraclinical methods were introduced in…”
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The B Cell — Old Player, New Position on the Team by McFarland, Henry F

“…The benefits of therapies targeting B cells in autoimmune diseases have led to increased interest in the role of B cells in diseases that have been thought to…”
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Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis by Polman, Chris H, Prof, Bertolotto, Antonio, MD, Deisenhammer, Florian, Prof, Giovannoni, Gavin, Prof, Hartung, Hans-Peter, Prof, Hemmer, Bernhard, Prof, Killestein, Joep, MD, McFarland, Henry F, MD, Oger, Joel, Prof, Pachner, Andrew R, Prof, Petkau, John, Prof, Reder, Anthony T, MD, Reingold, Stephen C, PhD, Schellekens, Huub, Prof, Sørensen, Per Soelberg, Prof

“…Summary The identification of factors that can affect the efficacy of immunomodulatory drugs in relapsing-remitting multiple sclerosis (MS) is important. For…”
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Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients by Muraro, Paolo A, Douek, Daniel C, Packer, Amy, Chung, Katherine, Guenaga, Francisco J, Cassiani-Ingoni, Riccardo, Campbell, Catherine, Memon, Sarfraz, Nagle, James W, Hakim, Frances T, Gress, Ronald E, McFarland, Henry F, Burt, Richard K, Martin, Roland

“…Clinical trials have indicated that autologous hematopoietic stem cell transplantation (HSCT) can persistently suppress inflammatory disease activity in a…”
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Myelin basic protein-specific TCR/HLA-DRB501:01 transgenic mice support the etiologic role of DRB501:01 in multiple sclerosis by Quandt, Jacqueline A, Huh, Jaebong, Baig, Mirza, Yao, Karen, Ito, Naoko, Bryant, Mark, Kawamura, Kazuyuki, Pinilla, Clemencia, McFarland, Henry F, Martin, Roland, Ito, Kouichi

“…Genetic susceptibility to multiple sclerosis (MS) has been linked to the HLA-DR15 haplotype consisting of DRB1*15:01(DR2b) and DRB5*01:01(DR2a) alleles. Given…”
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Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis by McDonald, W. Ian, Compston, Alistair, Edan, Gilles, Goodkin, Donald, Hartung, Hans-Peter, Lublin, Fred D., McFarland, Henry F., Paty, Donald W., Polman, Chris H., Reingold, Stephen C., Sandberg-Wollheim, Magnhild, Sibley, William, Thompson, Alan, Van Den Noort, Stanley, Weinshenker, Brian Y., Wolinsky, Jerry S.

“…The International Panel on MS Diagnosis presents revised diagnostic criteria for multiple sclerosis (MS). The focus remains on the objective demonstration of…”
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Humanized Anti-CD25 (Daclizumab) Inhibits Disease Activity in Multiple Sclerosis Patients Failing to Respond to Interferon β by Bielekova, Bibiana, Richert, Nancy, Howard, Thomas, Blevins, Gregg, Markovic-Plese, Silva, McCartin, Jennifer, Würfel, Jens, Ohayon, Joan, Waldmann, Thomas A., McFarland, Henry F., Martin, Roland

“…Identifying effective treatment combinations for MS patients failing standard therapy is an important goal. We report the results of a phase II open label…”
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Multiple sclerosis: a complicated picture of autoimmunity by McFarland, Henry F, Martin, Roland

“…Understanding of autoimmune diseases, including multiple sclerosis, has expanded considerably in recent years. New insights have been provided by not only…”
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Tissue Distribution and Variant Characterization of Human Herpesvirus (HHV)—6: Increased Prevalence of HHV-6A in Patients with Multiple Sclerosis by Akhyani, Nahid, Berti, Rossana, Brennan, Meghan B., Soldan, Samantha S., Eaton, Joan M., McFarland, Henry F., Jacobson, Steven

“…Human herpesvirus (HHV)—6 has been associated with the pathogenesis of multiple sclerosis (MS) on the basis of serologic, molecular, and histopathologic…”
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Immunological Aspects of Demyelinating Diseases by Martin, Roland, McFarland, Henry F, McFarlin, Dale E

“…Primary demyelination in the central nervous system results from damage to the myelin sheath or oligodendroglia and can be produced by a variety of mechanisms,…”
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Oral administration of the nitroxide radical TEMPOL exhibits immunomodulatory and therapeutic properties in multiple sclerosis models by Neil, Sarah, Huh, Jaebong, Baronas, Victoria, Li, Xinhui, McFarland, Henry F, Cherukuri, Murali, Mitchell, James B, Quandt, Jacqueline A

“…Highlights • The nitroxide radical TEMPOL given orally limits clinical disease in models of MS. • TEMPOL reduced inflammatory infiltrates and preserved…”
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Immunotherapy of multiple sclerosis: Where are we? Where should we go? by Martin, Roland, Stürzebecher, Claus-Steffen, McFarland, Henry F

“…Differences in multiple sclerosis patient's disease and their responses to standard drugs indicate that today's therapies need to be more individualized. It is…”
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Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination by YUEN, Tracy J, JOHNSON, Kory R, FFRENCH-CONSTANT, Charles, MIRON, Veronique E, CHAO ZHAO, QUANDT, Jacqueline, HARRISINGH, Marie C, SWIRE, Matthew, WILLIAMS, Anna, MCFARLAND, Henry F, FRANKLIN, Robin J. M

“…The development of new regenerative therapies for multiple sclerosis is hindered by the lack of potential targets for enhancing remyelination. The study of…”
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Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand by Martin, Roland, Bielekova, Bibiana, Goodwin, Bonnie, Richert, Nancy, Cortese, Irene, Kondo, Takayuki, Afshar, Ghazaleh, Gran, Bruno, Eaton, Joan, Antel, Jack, Frank, Joseph A, McFarland, Henry F

“…Myelin-specific T lymphocytes are considered essential in the pathogenesis of multiple sclerosis. The myelin basic protein peptide (a.a. 83-99) represents one…”
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Evolution of T1 black holes in patients with multiple sclerosis imaged monthly for 4 years by Bagnato, Francesca, Jeffries, Neal, Richert, Nancy D., Stone, Roger D., Ohayon, Joan M., McFarland, Henry F., Frank, Joseph A.

“…T1 black holes (BHs) on MRIs may represent either areas of oedema or axonal loss in patients with multiple sclerosis. BHs begin as contrast enhancing lesions…”
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Alemtuzumab versus interferon beta-1a: implications for pathology and trial design by McFarland, Henry F

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Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease by Bomprezzi, Roberto, Ringnér, Markus, Kim, Seungchan, Bittner, Michael L., Khan, Javed, Chen, Yidong, Elkahloun, Abdel, Yu, Aimee, Bielekova, Bibiana, Meltzer, Paul S., Martin, Roland, McFarland, Henry F., Trent, Jeffrey M.

“…Multiple sclerosis (MS) and other T cell-mediated autoimmune diseases develop in individuals carrying a complex susceptibility trait, probably following…”
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Clustering of Non-Major Histocompatibility Complex Susceptibility Candidate Loci in Human Autoimmune Diseases by Becker, Kevin G., Simon, Richard M., Bailey-Wilson, Joan E., Freidlin, Boris, Biddison, William E., McFarland, Henry F., Trent, Jeffrey M.

“…Human autoimmune diseases are thought to develop through a complex combination of genetic and environmental factors. Genome-wide linkage searches of autoimmune…”
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Treatment with the phosphodiesterase type-4 inhibitor rolipram fails to inhibit blood—brain barrier disruption in multiple sclerosis by Bielekova, Bibiana, Richert, Nancy, Howard, Thomas, Packer, Amy N, Blevins, Gregg, Ohayon, Joan, McFarland, Henry F, Stürzebecher, Claus-Steffen, Martin, Roland

“…Rolipram, a prototypic phosphodiesterase-4 inhibitor, is highly effective in suppressing Th1 autoimmunity in multiple animal models, including experimental…”
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Central nervous system disease in primary Sjögren’s syndrome: The role of magnetic resonance imaging by Morgen, Katrin, McFarland, Henry F., Pillemer, Stanley R.

“…To examine the frequency of central nervous system (CNS) disease in primary Sjögren’s syndrome (pSS) and indicate ways in which cerebral magnetic resonance…”
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