Search Results - "McFarland, HF"

Differential diagnosis of suspected multiple sclerosis: a consensus approach by Miller, DH, Weinshenker, BG, Filippi, M, Banwell, BL, Cohen, JA, Freedman, MS, Galetta, SL, Hutchinson, M, Johnson, RT, Kappos, L, Kira, J, Lublin, FD, McFarland, HF, Montalban, X, Panitch, H, Richert, JR, Reingold, SC, Polman, CH

“…Background and objectives Diagnosis of multiple sclerosis (MS) requires exclusion of diseases that could better explain the clinical and paraclinical findings…”
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Complexities in the Treatment of Autoimmune Disease by McFarland, Henry F.

“…Excitement has been high in the immunological community, as animal and human studies have suggested that autoimmune diseases can be prevented or inhibited by…”
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Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria" by Polman, Chris H., Reingold, Stephen C., Edan, Gilles, Filippi, Massimo, Hartung, Hans-Peter, Kappos, Ludwig, Lublin, Fred D., Metz, Luanne M., McFarland, Henry F., O'Connor, Paul W., Sandberg-Wollheim, Magnhild, Thompson, Alan J., Weinshenker, Brian G., Wolinsky, Jerry S.

“…New diagnostic criteria for multiple sclerosis integrating magnetic resonance image assessment with clinical and other paraclinical methods were introduced in…”
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Interferon beta-1b in secondary progressive MS: Results from a 3-year controlled study by Panitch, Hillel, Miller, Aaron, Paty, Donald, Weinshenker, Brian

“…To evaluate the efficacy and safety of interferon beta-1b (IFNbeta-1b) in subjects with secondary progressive multiple sclerosis (SPMS). This 3-year,…”
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Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients by Muraro, Paolo A, Douek, Daniel C, Packer, Amy, Chung, Katherine, Guenaga, Francisco J, Cassiani-Ingoni, Riccardo, Campbell, Catherine, Memon, Sarfraz, Nagle, James W, Hakim, Frances T, Gress, Ronald E, McFarland, Henry F, Burt, Richard K, Martin, Roland

“…Clinical trials have indicated that autologous hematopoietic stem cell transplantation (HSCT) can persistently suppress inflammatory disease activity in a…”
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Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis by McDonald, W. Ian, Compston, Alistair, Edan, Gilles, Goodkin, Donald, Hartung, Hans-Peter, Lublin, Fred D., McFarland, Henry F., Paty, Donald W., Polman, Chris H., Reingold, Stephen C., Sandberg-Wollheim, Magnhild, Sibley, William, Thompson, Alan, Van Den Noort, Stanley, Weinshenker, Brian Y., Wolinsky, Jerry S.

“…The International Panel on MS Diagnosis presents revised diagnostic criteria for multiple sclerosis (MS). The focus remains on the objective demonstration of…”
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Humanized Anti-CD25 (Daclizumab) Inhibits Disease Activity in Multiple Sclerosis Patients Failing to Respond to Interferon β by Bielekova, Bibiana, Richert, Nancy, Howard, Thomas, Blevins, Gregg, Markovic-Plese, Silva, McCartin, Jennifer, Würfel, Jens, Ohayon, Joan, Waldmann, Thomas A., McFarland, Henry F., Martin, Roland

“…Identifying effective treatment combinations for MS patients failing standard therapy is an important goal. We report the results of a phase II open label…”
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Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand by Martin, Roland, Bielekova, Bibiana, Goodwin, Bonnie, Richert, Nancy, Cortese, Irene, Kondo, Takayuki, Afshar, Ghazaleh, Gran, Bruno, Eaton, Joan, Antel, Jack, Frank, Joseph A, McFarland, Henry F

“…Myelin-specific T lymphocytes are considered essential in the pathogenesis of multiple sclerosis. The myelin basic protein peptide (a.a. 83-99) represents one…”
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CD4+CD28- costimulation-independent T cells in multiple sclerosis by Markovic-Plese, S, Cortese, I, Wandinger, K P, McFarland, H F, Martin, R

“…Multiple lines of evidence suggest that CD4+ lymphocytes initiate autoimmune responses against myelin antigens in multiple sclerosis (MS). The increased…”
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Expression profiling identifies responder and non‐responder phenotypes to interferon‐β in multiple sclerosis by Stürzebecher, S., Wandinger, K. P., Rosenwald, A., Sathyamoorthy, M., Tzou, A., Mattar, P., Frank, J. A., Staudt, L., Martin, R., McFarland, H. F.

“…Autoimmune diseases such as multiple sclerosis are characterized by complex genetic traits and pathomechanisms that translate into clinical heterogeneity. This…”
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Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease by Bomprezzi, Roberto, Ringnér, Markus, Kim, Seungchan, Bittner, Michael L., Khan, Javed, Chen, Yidong, Elkahloun, Abdel, Yu, Aimee, Bielekova, Bibiana, Meltzer, Paul S., Martin, Roland, McFarland, Henry F., Trent, Jeffrey M.

“…Multiple sclerosis (MS) and other T cell-mediated autoimmune diseases develop in individuals carrying a complex susceptibility trait, probably following…”
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Clustering of Non-Major Histocompatibility Complex Susceptibility Candidate Loci in Human Autoimmune Diseases by Becker, Kevin G., Simon, Richard M., Bailey-Wilson, Joan E., Freidlin, Boris, Biddison, William E., McFarland, Henry F., Trent, Jeffrey M.

“…Human autoimmune diseases are thought to develop through a complex combination of genetic and environmental factors. Genome-wide linkage searches of autoimmune…”
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The role of magnetic resonance techniques in understanding and managing multiple sclerosis by MILLER, D. H, GROSSMAN, R. I, REINGOLD, S. C, MCFARLAND, H. F

“…Magnetic resonance (MR) techniques have had a major impact in the last 10-15 years in understanding and managing multiple sclerosis. This review summarizes the…”
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Treatment with the phosphodiesterase type-4 inhibitor rolipram fails to inhibit blood—brain barrier disruption in multiple sclerosis by Bielekova, Bibiana, Richert, Nancy, Howard, Thomas, Packer, Amy N, Blevins, Gregg, Ohayon, Joan, McFarland, Henry F, Stürzebecher, Claus-Steffen, Martin, Roland

“…Rolipram, a prototypic phosphodiesterase-4 inhibitor, is highly effective in suppressing Th1 autoimmunity in multiple animal models, including experimental…”
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Central nervous system disease in primary Sjögren’s syndrome: The role of magnetic resonance imaging by Morgen, Katrin, McFarland, Henry F., Pillemer, Stanley R.

“…To examine the frequency of central nervous system (CNS) disease in primary Sjögren’s syndrome (pSS) and indicate ways in which cerebral magnetic resonance…”
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Complex immunomodulatory effects of interferon-β in multiple sclerosis include the upregulation of T helper 1-associated marker genes by Wandinger, Klaus-Peter, Stürzebecher, Claus-Steffen, Bielekova, Bibiana, Detore, Greg, Rosenwald, Andreas, Staudt, Louis M., McFarland, Henry F., Martin, Roland

“…Multiple sclerosis (MS) is considered an autoimmune disease that is mediated by proinflammatory T helper‐1 lymphocytes. The putative mechanism of interferon‐β…”
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MRI as a marker for disease heterogeneity in multiple sclerosis by BIELEKOVA, B, KADOM, N, MARTIN, R, CUTTER, G, MCFARLAND, H. F, FISHER, E, JEFFRIES, N, OHAYON, J, RICHERT, N, HOWARD, T, BASH, C. N, FRANK, J. A, STONE, L

“…Whereas recent data from imaging studies challenge the prevailing notion that multiple sclerosis (MS) is purely an inflammatory disease, pathologic studies…”
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The role of MRI as a surrogate outcome measure in multiple sclerosis by McFarland, H F, Barkhof, F, Antel, J, Miller, D H

“…The need for more specific and more sensitive outcome measures for use in testing new therapies in multiple sclerosis (MS) is generally accepted. This need has…”
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Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA by Soldan, Samantha S, Berti, Rossana, Salem, Nazi, Secchiero, Paola, Flamand, Louis, Calabresi, Peter A, Brennan, Meghan B, Maloni, Heidi W, Mcfarland, Henry F, Lin, Hun-Chi, Patnaik, Madhumita, Jacobson, Steven

“…Viruses have long been suggested to be involved in the etiology of multiple sclerosis (MS). This suggestion is based on (1) epidemiological evidence of…”
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Interferon-beta-1b slows progression of atrophy in RRMS: Three-year follow-up in NAb- and NAb+ patients by Frank, J A, Richert, N, Bash, C, Stone, L, Calabresi, P A, Lewis, B, Stone, R, Howard, T, McFarland, H F

“…To determine the effect of interferon-beta-1b (IFNbeta-1b) treatment on total contrast-enhancing lesions (CEL), white matter lesion load (WMLL), and cerebral…”
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