Search Results - "McEwan, Phil"

Review of Utility Values for Economic Modeling in Type 2 Diabetes by Beaudet, Amélie, BPharm, MSc, Clegg, John, BSc, Thuresson, Per-Olof, MPharm, MSc, Lloyd, Adam, MPhil, McEwan, Phil, BA (Hons), PhD

“…Abstract Objectives Economic analysis in type 2 diabetes mellitus (T2DM) requires an assessment of the effect of a wide range of complications. The objective…”
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Predicting atrial fibrillation in primary care using machine learning by Hill, Nathan R, Ayoubkhani, Daniel, McEwan, Phil, Sugrue, Daniel M, Farooqui, Usman, Lister, Steven, Lumley, Matthew, Bakhai, Ameet, Cohen, Alexander T, O'Neill, Mark, Clifton, David, Gordon, Jason

“…Atrial fibrillation (AF) is the most common sustained heart arrhythmia. However, as many cases are asymptomatic, a large proportion of patients remain…”
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Validation of the IMS CORE Diabetes Model by McEwan, Phil, PhD, Foos, Volker, MSc, Palmer, James L., MSc, Lamotte, Mark, MD, Lloyd, Adam, MPhil, Grant, David, MBA

“…Abstract Background The IMS CORE Diabetes Model (CDM) is a widely published and validated simulation model applied in both type 1 diabetes mellitus (T1DM) and…”
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The Impact of CKD Anaemia on Patients: Incidence, Risk Factors, and Clinical Outcomes—A Systematic Literature Review by McEwan, Phil, van Haalen, Heleen, Grandy, Susan, Palaka, Eirini, Darlington, Oliver

“…Anaemia is a common consequence of chronic kidney disease (CKD); however, the risk factors for its development and its impact on outcomes have not been well…”
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Cost‐effectiveness of dapagliflozin as an adjunct to insulin for the treatment of type 1 diabetes mellitus in the United Kingdom by Bennett, Hayley, Tank, Amarjeet, Evans, Marc, Bergenheim, Klas, McEwan, Phil

“…Aims To assess the cost‐effectiveness of dapagliflozin, a sodium‐glucose co‐transporter‐2 (SGLT2) inhibitor, as an adjunct to insulin in adults with type 1…”
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Resource use and direct medical costs of acute respiratory illness in the UK based on linked primary and secondary care records from 2001 to 2009 by Meier, Genevieve C, Watkins, John, McEwan, Phil, Pockett, Rhys D

“…Background Previous studies have shown that influenza is associated with a substantial healthcare burden in the United Kingdom (UK), but more studies are…”
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Real-World Associations of Renin-Angiotensin-Aldosterone System Inhibitor Dose, Hyperkalemia, and Adverse Clinical Outcomes in a Cohort of Patients With New-Onset Chronic Kidney Disease or Heart Failure in the United Kingdom by Linde, Cecilia, Bakhai, Ameet, Furuland, Hans, Evans, Marc, McEwan, Phil, Ayoubkhani, Daniel, Qin, Lei

“…Background Dosing of renin-angiotensin-aldosterone system inhibitors (RAASi) may be modified to manage associated hyperkalemia risk; however, this approach…”
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Characterizing unmet medical need and the potential role of new biologic treatment options in patients with ulcerative colitis and Crohn’s disease: a systematic review and clinician surveys by Gordon, Jason P, McEwan, Phil C, Maguire, Andy, Sugrue, Daniel M, Puelles, Jorge

“…OBJECTIVESComparative outcomes of patients with ulcerative colitis (UC) and Crohn’s disease (CD) prescribed a biologic therapy are inconclusive. The aim of…”
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Conceptualizing a Model: A Report of the ISPOR-SMDM Modeling Good Research Practices Task Force-2 by Roberts, Mark, MD, MPP, Russell, Louise B., PhD, Paltiel, A. David, PhD, Chambers, Michael, MSc, MA, McEwan, Phil, PhD, Krahn, Murray, MD, MSc

“…Abstract The appropriate development of a model begins with understanding the problem that is being represented. The aim of this article was to provide a…”
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The Health Economic Value of Changes in Glycaemic Control, Weight and Rates of Hypoglycaemia in Type 1 Diabetes Mellitus by McEwan, Phil, Bennett, Hayley, Fellows, Jonathan, Priaulx, Jennifer, Bergenheim, Klas

“…Therapy-related consequences of treatment for type 1 diabetes mellitus (T1DM), such as weight gain and hypoglycaemia, act as a barrier to attaining optimal…”
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Cost effectiveness of sodium zirconium cyclosilicate for the treatment of hyperkalaemia in patients with CKD in Norway and Sweden by Kim, Kun, Fagerström, Josefine, Chen, Gengshi, Lagunova, Zoya, Furuland, Hans, McEwan, Phil

“…Abstract Background Hyperkalaemia is common in patients with chronic kidney disease (CKD) and is associated with a range of adverse outcomes. Historically,…”
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Modelling the long-term benefits of tolvaptan therapy on renal function decline in autosomal dominant polycystic kidney disease: an exploratory analysis using the ADPKD outcomes model by Bennett, Hayley, McEwan, Phil, Hamilton, Karina, O'Reilly, Karl

“…The short-term efficacy of tolvaptan in patients with autosomal dominant polycystic kidney disease (ADPKD) has been demonstrated across several phase 3 trials,…”
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Estimating the Value of New Antimicrobials in the Context of Antimicrobial Resistance: Development and Application of a Dynamic Disease Transmission Model by Gordon, Jason, Darlington, Oliver, McEwan, Phil, Lumley, Matthew, Taie, Amer, Hicks, Meagen, Charbonneau, Claudie, Blake, Angela, Hawkins, Neil, Goldenberg, Simon, Otter, Jonathan, Wilcox, Mark

“…Objectives Antimicrobial resistance (AMR) represents a significant threat to patient and population health. The study aim was to develop and validate a model…”
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Cost-effectiveness of fluocinolone acetonide implant (ILUVIEN®) in UK patients with chronic diabetic macular oedema considered insufficiently responsive to available therapies by Pochopien, Michal, Beiderbeck, Annette, McEwan, Phil, Zur, Richard, Toumi, Mondher, Aballéa, Samuel

“…Diabetic macular oedema (DMO) may lead to visual loss and blindness. Several pharmacological treatments are available on the National Health Service (NHS) to…”
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Assessing the Long-Term Impact of Treating Hepatitis C Virus (HCV)-Infected People Who Inject Drugs in the UK and the Relationship between Treatment Uptake and Efficacy on Future Infections by Bennett, Hayley, McEwan, Phil, Sugrue, Daniel, Kalsekar, Anupama, Yuan, Yong

“…The prevalence of the hepatitis C virus (HCV) remains high amongst people who inject drugs (PWID) and accounts for the majority of newly acquired infections…”
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Estimating the Cost-Effectiveness of One-Time Screening and Treatment for Hepatitis C in Korea by Kim, Do Young, Han, Kwang-Hyub, Jun, Byungyool, Kim, Tae Hyun, Park, Sohee, Ward, Thomas, Webster, Samantha, McEwan, Phil

“…This study aims to investigate the cost-effectiveness of a one-time hepatitis C virus (HCV) screening and treatment program in South Korea where hepatitis B…”
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Estimating the clinical and economic benefit associated with incremental improvements in sustained virologic response in chronic hepatitis C by McEwan, Phil, Ward, Thomas, Bennett, Hayley, Kalsekar, Anupama, Webster, Samantha, Brenner, Michael, Yuan, Yong

“…Hepatitis C virus (HCV) infection is one of the principle causes of chronic liver disease. Successful treatment significantly decreases the risk of hepatic…”
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The effect of hyperkalemia and long inter-dialytic interval on morbidity and mortality in patients receiving hemodialysis: a systematic review by Bem, Danai, Sugrue, Daniel, Wilding, Ben, Zile, Ina, Butler, Karin, Booth, David, Tafesse, Eskinder, McEwan, Phil

“…Patients with chronic kidney disease, especially those receiving hemodialysis (HD), are at risk of hyperkalemia (HK). This systematic review aimed to evaluate…”
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Serum potassium and clinical outcomes in heart failure patients: results of risk calculations in 21 334 patients in the UK by Linde, Cecilia, Qin, Lei, Bakhai, Ameet, Furuland, Hans, Evans, Marc, Ayoubkhani, Daniel, Palaka, Eirini, Bennett, Hayley, McEwan, Phil

“…Aims At present, the clinical burden of hypokalaemia and hyperkalaemia among European heart failure patients, and relationships between serum potassium and…”
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Body mass index and risk of obesity‐related conditions in a cohort of 2.9 million people: Evidence from a UK primary care database by Haase, Christiane L., Eriksen, Kirsten T., Lopes, Sandra, Satylganova, Altynai, Schnecke, Volker, McEwan, Phil

“…Objective Obesity rates in the United Kingdom are some of the highest in Western Europe, with considerable clinical and societal impacts. Obesity is associated…”
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