Search Results - "McEwan, I."
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Molecular mechanisms of androgen receptor-mediated gene regulation: structure-function analysis of the AF-1 domain
Published in Endocrine-related cancer (01-06-2004)“…The androgen receptor is a ligand-activated transcription factor that binds DNA response elements as a homodimer. Binding sites for the receptor have been…”
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Omega-3 fatty acids and vitamin D in immobilisation: Part A- Modulation of appendicular mass content, composition and structure
Published in The Journal of nutrition, health & aging (01-01-2017)“…Objectives Muscle size decreases in response to short-term limb immobilisation. This study set out to determine whether two potential protein-sparing…”
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Omega-3 fatty acids and vitamin D in immobilisation: Part B- Modulation of muscle functional, vascular and activation profiles
Published in The Journal of nutrition, health & aging (01-01-2017)“…Objectives This study set out to determine whether two potential protein-sparing modulators (eicosapentaenoic acid and vitamin D) would modulate the…”
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The human androgen receptor AF1 transactivation domain: interactions with transcription factor IIF and molten-globule-like structural characteristics
Published in Biochemical Society transactions (01-12-2006)“…The AR (androgen receptor) is a ligand-activated transcription factor and member of the steroid receptor superfamily. The AR responds to the ligands…”
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A COMBINED MODAL/FINITE ELEMENT ANALYSIS TECHNIQUE FOR THE DYNAMIC RESPONSE OF A NON-LINEAR BEAM TO HARMONIC EXCITATION
Published in Journal of sound and vibration (14-06-2001)“…In this paper, a method is proposed for modelling large deflection beam response involving multiple vibration modes. Significant savings in computational time…”
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Crust strength: a wind tunnel study of the effect of impact by saltating particles on cohesive soil surfaces
Published in Earth surface processes and landforms (01-07-2001)“…A wind tunnel study examined the effect of distributions of saltating particles on sediment surfaces which were characterized by distributions of their tensile…”
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The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision
Published in Anesthesiology (Philadelphia) (01-10-1994)“…We have previously demonstrated that the minimum alveolar concentration of isoflurane at 1 atm that is required to prevent movement in 50% of patients or…”
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Structural and functional alterations in the androgen receptor in spinal bulbar muscular atrophy
Published in Biochemical Society transactions (01-05-2001)“…The androgen receptor is a member of the nuclear receptor superfamily, and regulates gene expression in response to the steroid hormones testosterone and…”
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The relationship between sediment mobilisation and the entry of Baetis mayflies into the water column in a laboratory flume
Published in Hydrobiologia (01-01-2005)“…Mass bedload movement is thought to play a key role in initiating stream invertebrate drift during extreme flood events. However, little is known of the…”
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10
Structural dynamics of the human androgen receptor: implications for prostate cancer and neurodegenerative disease
Published in Biochemical Society transactions (01-12-2006)“…The AR (androgen receptor) is a ligand-activated transcription factor that mediates the action of the steroids testosterone and dihydrotestosterone…”
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Impact of repeated surgical procedures on the incidence and prevalence of latex allergy: A prospective study of 1263 children
Published in The Journal of pediatrics (01-04-2002)“…Assessment with questionnaire, skin tests, and immunoglobulin E measurements showed 6 (0.5%) of 1263 children having elective surgery had latex allergy; 50…”
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12
Role of conserved hydrophobic amino acids in androgen receptor AF-1 function
Published in Journal of molecular endocrinology (01-12-2003)“…The intracellular androgen receptor (AR) is a ligand-activated transcription factor. Upon binding the steroids testosterone or dihydrotestosterone, the…”
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13
Stature loss and recovery following a period of loading: Effect of time of day and presence or absence of low back pain
Published in Clinical biomechanics (Bristol) (01-07-2008)“…Abstract Background Stature reductions in asymptomatic individuals, caused by a set load, are lower later in the day when stature is in the trough of diurnal…”
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14
The androgen receptor transactivation domain: the interplay between protein conformation and protein-protein interactions
Published in Biochemical Society transactions (01-10-2003)“…The AR (androgen receptor) belongs to the nuclear receptor superfamily and directly regulates patterns of gene expression in response to the steroids…”
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The influence of different unloading positions upon stature recovery and paraspinal muscle activity
Published in Clinical biomechanics (Bristol) (01-05-2005)“…Objective. To determine whether stature recovery and paraspinal muscle activity can be altered in individuals with and without chronic low-back pain by…”
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Analysis of small-scale gravel bed topography during armoring
Published in Water resources research (01-12-2003)“…In evaluating the resistance of sediment particles to entrainment by the action of the flow in a river, the grain geometry is usually characterized using…”
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Induced α-Helix Structure in AF1 of the Androgen Receptor upon Binding Transcription Factor TFIIF
Published in Biochemistry (Easton) (23-03-2004)“…In recent years, it has become clear that in many proteins, significant regions are encoded by amino acid sequences that do not automatically fold into their…”
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Investigation of Hydrogen-Bonding Structure in Blends of Poly(N-vinylpyrrolidone) with Poly(vinyl acetate-co-vinyl alcohol) Using Positron Annihilation
Published in Macromolecules (25-09-2001)“…The effect of hydrogen bonding on the free volume in polymer blends is reported using infrared spectroscopy and positron annihilation lifetime spectroscopy…”
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Conformational analysis of the androgen receptor amino-terminal domain involved in transactivation. Influence of structure-stabilizing solutes and protein-protein interactions
Published in The Journal of biological chemistry (31-05-2002)“…The androgen receptor (AR) is a member of the nuclear receptor superfamily. Sequences within the large amino-terminal domain of the receptor have been shown to…”
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Straight Benthic Flow-Through Flume for In Situ Measurement of Cohesive Sediment Dynamics
Published in Journal of hydraulic engineering (New York, N.Y.) (01-01-2003)“…The design of a straight benthic flow-through flume for in situ studies of cohesive sediment dynamics is described including the flume structure and probes…”
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