Search Results - "McEvoy, Justina"

TNF Counterbalances the Emergence of M2 Tumor Macrophages by Kratochvill, Franz, Neale, Geoffrey, Haverkamp, Jessica M., Van de Velde, Lee-Ann, Smith, Amber M., Kawauchi, Daisuke, McEvoy, Justina, Roussel, Martine F., Dyer, Michael A., Qualls, Joseph E., Murray, Peter J.

“…Cancer can involve non-resolving, persistent inflammation where varying numbers of tumor-associated macrophages (TAMs) infiltrate and adopt different…”
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Genetic and Epigenetic Discoveries in Human Retinoblastoma by McEvoy, Justina D, Dyer, Michael A

“…Retinoblastoma is a rare pediatric cancer of the retina. Nearly all retinoblastomas are initiated through the biallelic inactivation of the retinoblastoma…”
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Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma by McEvoy, Justina, Ulyanov, Anatoly, Brennan, Rachel, Wu, Gang, Pounds, Stanley, Zhang, Jinghui, Dyer, Michael A

“…Retinoblastoma is a childhood cancer of the developing retina that begins in utero and is diagnosed in the first years of life. Biallelic RB1 gene inactivation…”
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Coexpression of Normally Incompatible Developmental Pathways in Retinoblastoma Genesis by McEvoy, Justina, Flores-Otero, Jacqueline, Zhang, Jiakun, Nemeth, Katie, Brennan, Rachel, Bradley, Cori, Krafcik, Fred, Rodriguez-Galindo, Carlos, Wilson, Matthew, Xiong, Shunbin, Lozano, Guillermina, Sage, Julien, Fu, Ligia, Louhibi, Lotfi, Trimarchi, Jeff, Pani, Amar, Smeyne, Richard, Johnson, Dianna, Dyer, Michael A.

“…It is widely believed that the molecular and cellular features of a tumor reflect its cell of origin and can thus provide clues about treatment targets. The…”
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RB1 gene inactivation by chromothripsis in human retinoblastoma by McEvoy, Justina, Nagahawatte, Panduka, Finkelstein, David, Richards-Yutz, Jennifer, Valentine, Marcus, Ma, Jing, Mullighan, Charles, Song, Guangchun, Chen, Xiang, Wilson, Matthew, Brennan, Rachel, Pounds, Stanley, Becksfort, Jared, Huether, Robert, Lu, Charles, Fulton, Robert S, Fulton, Lucinda L, Hong, Xin, Dooling, David J, Ochoa, Kerri, Mardis, Elaine R, Wilson, Richard K, Easton, John, Zhang, Jinghui, Downing, James R, Ganguly, Arupa, Dyer, Michael A

“…Retinoblastoma is a rare childhood cancer of the developing retina. Most retinoblastomas initiate with biallelic inactivation of the RB1 gene through diverse…”
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Subcellular localization and cytoplasmic complex status of endogenous Keap1 by Watai, Yoriko, Kobayashi, Akira, Nagase, Hiroko, Mizukami, Mio, McEvoy, Justina, Singer, Jeffrey D, Itoh, Ken, Yamamoto, Masayuki

“…Keap1 acts as a sensor for oxidative/electrophilic stress, an adaptor for Cullin-3-based ubiquitin ligase, and a regulator of Nrf2 activity through the…”
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Constitutive Turnover of Cyclin E by Cul3 Maintains Quiescence by McEvoy, Justina D., Kossatz, Uta, Malek, Nisar, Singer, Jeffrey D.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cross-species genomic and epigenomic landscape of retinoblastoma by Benavente, Claudia A, McEvoy, Justina D, Finkelstein, David, Wei, Lei, Kang, Guolian, Wang, Yong-Dong, Neale, Geoffrey, Ragsdale, Susan, Valentine, Virginia, Bahrami, Armita, Temirov, Jamshid, Pounds, Stanley, Zhang, Jinghui, Dyer, Michael A

“…Genetically engineered mouse models (GEMMs) of human cancer are important for advancing our understanding of tumor initiation and progression as well as for…”
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Changes in Retinoblastoma Cell Adhesion Associated with Optic Nerve Invasion by Laurie, Nikia, Mohan, Adithi, McEvoy, Justina, Reed, Damon, Zhang, Jiakun, Schweers, Brett, Ajioka, Itsuki, Valentine, Virginia, Johnson, Dianna, Ellison, David, Dyer, Michael A.

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The role of the Rb family during mouse retinal development by Ajioka, Itsuki, McEvoy, Justina, Nakajima, Kazunori, Dyer, Michael

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Abstract B26: Novel lncRNA regulates PAX3/FOXO1 expression and is essential for RMS tumorigenesis by Chen, Xiang, Herrera-Herrera, Mireya, McEvoy, Justina

“…Abstract Rhabdomyosarcoma (RMS) is a pediatric cancer of the developing skeletal muscle, and the mechanisms that drive this tumor are not completely…”
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Abstract 3873: Novel non-genetic mechanisms drive rhabdomyosarcoma tumorigenesis by McEvoy, Justina, Dyer, Michael, Chen, Xiang

“…Abstract Most pediatric solid tumors originate from perturbations during development, however the mechanisms that drive these disruptions and promote tumor…”
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Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses by Stewart, Elizabeth, McEvoy, Justina, Wang, Hong, Chen, Xiang, Honnell, Victoria, Ocarz, Monica, Gordon, Brittney, Dapper, Jason, Blankenship, Kaley, Yang, Yanling, Li, Yuxin, Shaw, Timothy I., Cho, Ji-Hoon, Wang, Xusheng, Xu, Beisi, Gupta, Pankaj, Fan, Yiping, Liu, Yu, Rusch, Michael, Griffiths, Lyra, Jeon, Jongrye, Freeman, Burgess B., Clay, Michael R., Pappo, Alberto, Easton, John, Shurtleff, Sheila, Shelat, Anang, Zhou, Xin, Boggs, Kristy, Mulder, Heather, Yergeau, Donald, Bahrami, Armita, Mardis, Elaine R., Wilson, Richard K., Zhang, Jinghui, Peng, Junmin, Downing, James R., Dyer, Michael A.

“…Personalized cancer therapy targeting somatic mutations in patient tumors is increasingly being incorporated into practice. Other therapeutic vulnerabilities…”
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The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma by Patel, Anand G., Chen, Xiang, Huang, Xin, Clay, Michael R., Komarova, Natalia L., Krasin, Matthew J., Pappo, Alberto, Tillman, Heather, Orr, Brent A., McEvoy, Justina, Gordon, Brittney, Blankenship, Kaley, Reilly, Colleen, Zhou, Xin, Norrie, Jackie L., Karlstrom, Asa, Yu, Jiyang, Wodarz, Dominik, Stewart, Elizabeth, Dyer, Michael A.

“…Rhabdomyosarcoma (RMS) is a pediatric cancer with features of skeletal muscle; patients with unresectable or metastatic RMS fare poorly due to high rates of…”
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A novel retinoblastoma therapy from genomic and epigenetic analyses by Zhang, Jinghui, Benavente, Claudia A., McEvoy, Justina, Flores-Otero, Jacqueline, Ding, Li, Chen, Xiang, Ulyanov, Anatoly, Wu, Gang, Wilson, Matthew, Wang, Jianmin, Brennan, Rachel, Rusch, Michael, Manning, Amity L., Ma, Jing, Easton, John, Shurtleff, Sheila, Mullighan, Charles, Pounds, Stanley, Mukatira, Suraj, Gupta, Pankaj, Neale, Geoff, Zhao, David, Lu, Charles, Fulton, Robert S., Fulton, Lucinda L., Hong, Xin, Dooling, David J., Ochoa, Kerri, Naeve, Clayton, Dyson, Nicholas J., Mardis, Elaine R., Bahrami, Armita, Ellison, David, Wilson, Richard K., Downing, James R., Dyer, Michael A.

“…Retinoblastoma is an aggressive childhood cancer of the developing retina that is initiated by the biallelic loss of RB1 . Tumours progress very quickly…”
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Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma by Chen, Xiang, Stewart, Elizabeth, Shelat, Anang A., Qu, Chunxu, Bahrami, Armita, Hatley, Mark, Wu, Gang, Bradley, Cori, McEvoy, Justina, Pappo, Alberto, Spunt, Sheri, Valentine, Marcus B., Valentine, Virginia, Krafcik, Fred, Lang, Walter H., Wierdl, Monika, Tsurkan, Lyudmila, Tolleman, Viktor, Federico, Sara M., Morton, Chris, Lu, Charles, Ding, Li, Easton, John, Rusch, Michael, Nagahawatte, Panduka, Wang, Jianmin, Parker, Matthew, Wei, Lei, Hedlund, Erin, Finkelstein, David, Edmonson, Michael, Shurtleff, Sheila, Boggs, Kristy, Mulder, Heather, Yergeau, Donald, Skapek, Steve, Hawkins, Douglas S., Ramirez, Nilsa, Potter, Philip M., Sandoval, John A., Davidoff, Andrew M., Mardis, Elaine R., Wilson, Richard K., Zhang, Jinghui, Downing, James R., Dyer, Michael A.

“…Rhabdomyosarcoma is a soft-tissue sarcoma with molecular and cellular features of developing skeletal muscle. Rhabdomyosarcoma has two major histologic…”
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Abstract 143: Molecular profiling of tumor-initiation events in rhabdomyosarcoma uncovers mitochondrial vulnerabilities by Kalita, Bhargab, Martinez-Cebrian, Gerard, McEvoy, Justina, Gordon, Brittney, Blankenship, Kaley, Karlstorm, Asa, Stewart, Elizabeth, Dyer, Michael, Dynlacht, Brian

“…Abstract Background: Alveolar Rhabdomyosarcoma (ARMS) is a very aggressive soft tissue tumor affecting children and adolescents. It is found that pediatric…”
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Abstract 3570: Preservation of cellular heterogeneity in 3D and 2D cultures of pediatric solid tumors by McEvoy, Justina D., Allensworth, Melody, Franco, Mariajose, McDonald, Natalie, Gordon, Brittney, Patel, Anand, Stewart, Elizabeth, Dyer, Michael

“…Abstract Over the past 10 years, we have developed and characterized over 280 orthotopic patient derived xenografts (O-PDXs) representing 23 different types of…”
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Molecular analysis of solid tumors (MAST): A protocol for comprehensive preclinical evaluation of pediatric solid tumors by Federico, Sara Michele, Stewart, Elizabeth, Bradley, Cori, McEvoy, Justina, Loh, Amos, Shelat, Anang, Zhang, Jinghui, Chen, Xiang, Pappo, Alberto S., Dyer, Michael A.

“…Abstract only…”
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In vivo requirement of the Cul3 ubiquitin ligase in cyclin E degradation and maintenance of the cell cycle by McEvoy, Justina D

“…The ubiquitin-dependent pathway is the major mechanism for cellular proteolysis, which is facilitated by three major enzymes: the E1, E2 and E3 enzymes. Cullin…”
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