Search Results - "McEuen, A R"

Mucosal T‐cell phenotypes in persistent atopic and nonatopic rhinitis show an association with mast cells by Powe, D. G., Huskisson, R. S., Carney, A. S., Jenkins, D., McEuen, A. R., Walls, A. F., Jones, N. S.

“…Background:  Allergic rhinitis is characterized by selective expansion of T cell subsets with a CD4+ phenotype. Recently, we identified a subpopulation of…”
Get full text

Basophils, eosinophils, and mast cells in atopic and nonatopic asthma and in late-phase allergic reactions in the lung and skin by Macfarlane, Alison J., Kon, Onn M., Smith, Susan J., Zeibecoglou, Kyriaki, Khan, L.Nasreen, Barata, Luis T., McEuen, Alan R., Buckley, Mark G., Walls, Andrew F., Meng, Qiu, Humbert, Marc, Barnes, Neil C., Robinson, Douglas S., Ying, Sun, Kay, A.Barry

“…Background: Previous studies used indirect methods to identify basophils in the bronchi in asthma, and the numbers were not compared with eosinophils and mast…”
Get full text

Purification and characterization of mouse mast cell proteinase-2 and the differential expression and release of mouse mast cell proteinase-1 and -2 in vivo by Pemberton, A. D., Brown, J. K., Wright, S. H., Knight, P. A., McPhee, M. L., McEuen, A. R., Forse, P. A., Miller, H. R.P.

“…Summary Background Gastrointestinal nematode infection is associated with mucosal mast cell (MMC) hyperplasia. In the mouse, this is accompanied by the release…”
Get full text

Development and characterization of a monoclonal antibody specific for human basophils and the identification of a unique secretory product of basophil activation by McEuen, A R, Buckley, M G, Compton, S J, Walls, A F

“…Despite increasing evidence that basophils can infiltrate into inflamed tissues during allergic reactions, determination of the extent of infiltration and…”
Get more information

cDNA sequence of two sheep mast cell tryptases and the differential expression of tryptase and sheep mast cell proteinase-1 in lung, dermis and gastrointestinal tract by PEMBERTON, A. D, MCALEESE, S. M, HUNTLEY, J. F, COLLIE, D. D. S, SCUDAMORE, C. L, MCEUEN, A. R, WALLS, A. F, MILLER, H. R. P

“…Mast cell tryptases are a family of serine proteinases which are implicated in the proliferation of smooth muscle cells and fibroblasts, upregulation of…”
Get full text

The detection of mast cell subpopulations in formalin-fixed human tissues using a new monoclonal antibody specific for chymase by Buckley, Mark G., McEuen, Alan R., Walls, Andrew F.

“…Chymase is an important marker for human mast cells as well as a mediator of inflammation and matrix remodelling, but research into chymase‐containing mast…”
Get full text

The return of the basophil by Buckley, M. G., McEuen, A. R., Walls, A. F.

Get full text

Segmental Bronchoprovocation in Allergic Rhinitis Patients Affects Mast Cell and Basophil Numbers in Nasal and Bronchial Mucosa by BRAUNSTAHL, GERT-JAN, OVERBEEK, SHELLEY E, FOKKENS, WYTSKE J, KLEINJAN, ALEX, MCEUEN, ALAN R, WALLS, ANDREW F, HOOGSTEDEN, HENK C, PRINS, JAN-BAS

“…Mast cells and basophils are cells that play an important role in the initiation and control of allergic inflammation in asthma and rhinitis. This study was…”
Get full text

Release and inactivation of interleukin-4 by mast cells by Tunon de Lara, J M, Okayama, Y, McEuen, A R, Heusser, C H, Church, M K, Walls, A F

Get more information

C-C Chemokines in Allergen-Induced Late-Phase Cutaneous Responses in Atopic Subjects: Association of Eotaxin with Early 6-Hour Eosinophils, and of Eotaxin-2 and Monocyte Chemoattractant Protein-4 with the Later 24-Hour Tissue Eosinophilia, and Relationship to Basophils and Other C-C Chemokines (Monocyte Chemoattractant Protein-3 and RANTES) by Ying, Sun, Robinson, Douglas S, Meng, Qiu, Barata, Luis T, McEuen, Alan R, Buckley, Mark G, Walls, Andrew F, Askenase, Philip W, Kay, A. Barry

“…The relationship of expression of the C-C chemokines eotaxin, eotaxin 2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4 to the kinetics of…”
Get full text

Tryptase and agonists of PAR-2 induce the proliferation of human airway smooth muscle cells by Berger, Patrick, Perng, Diahn-Warng, Thabrew, Hiran, Compton, Steven J, Cairns, Jennifer A, McEuen, Alan R, Marthan, Roger, Tunon De Lara, Jose-Manuel, Walls, Andrew F

“…1  Immunopharmacology Group, Southampton General Hospital, Southampton SO16 6YD, United Kingdom; and 2  Laboratoire de Physiologie Cellulaire Respiratoire,…”
Get full text

The release of basogranulin in response to IgE-dependent and IgE-independent stimuli: Validity of basogranulin measurement as an indicator of basophil activation by Mochizuki, Akinori, McEuen, Alan R., Buckley, Mark G., Walls, Andrew F.

“…Background: Basogranulin, the novel basophil granule protein recognized by the monoclonal antibody BB1, can be released by stimulation with anti-IgE antibody…”
Get full text

Basophil and eosinophil accumulation and mast cell degranulation in the nasal mucosa of patients with hay fever after local allergen provocation by KleinJan, Alex, McEuen, Alan R., Dijkstra, Mariska D., Buckley, Mark G., Walls, Andrew F., Fokkens, Wytske J.

“…Background: Basophils and mast cells have certain similarities and are believed to be important in upper and lower respiratory allergy. Objective: We sought to…”
Get full text

Zinc binding by retroviral integrase by McEuen, A R, Edwards, B, Koepke, K A, Ball, A E, Jennings, B A, Wolstenholme, A J, Danson, M J, Hough, D W

“…Zinc binding by integrase from Moloney murine leukaemia virus and a protein A fusion protein containing integrase from human immunodeficiency virus type 1 was…”
Get more information

Inhibitors of chymase as mast cell-stabilizing agents: contribution of chymase in the activation of human mast cells by He, S, Gaça, M D, McEuen, A R, Walls, A F

“…There has long been evidence that inhibitors of chymotryptic proteinases can inhibit the degranulation of rodent mast cells, but their actions on human mast…”
Get more information

Calcium-containing crystals in Telfairia Hooker (Cucurbitaceae) by Okoli, B.E, McEuen, A.R

“…Polarized light and scanning electron microscopy were used to examine the distribution, location and form of crystals in the leaves, probracts, stems, flowers…”
Get full text

Mass, charge, and subcellular localization of a unique secretory product identified by the basophil-specific antibody BB1 by MCEUEN, Alan R, CALAFAT, Jero, COMPTON, Steven J, EASOM, Nicholas J. W, BUCKLEY, Mark G, KNOL, Edward F, WALLS, Andrew F

“…BB1 is a basophil-specific mAb (Lab Invest 1999;79:27-38). The identity of the corresponding antigen has not been determined, but it gives a granular…”
Get full text

Regulation of the activity of human chymase during storage and release from mast cells: The contributions of inorganic cations, pH, heparin and histamine by McEuen, Alan R., Sharma, Bhupinder, Walls, Andrew F.

“…Chymase, the major chymotryptic proteinase of human mast cells, can be released in substantial quantities following mast cell activation. As this enzyme is…”
Get full text

Chemokine-Induced Cutaneous Inflammatory Cell Infiltration in a Model of Hu-PBMC-SCID Mice Grafted with Human Skin by Fahy, Olivier, Porte, Henri, Sénéchal, Stéphanie, Vorng, Han, McEuen, Alan R., Buckley, Mark G., Walls, Andrew F., Wallaert, Benoît, Tonnel, André-Bernard, Tsicopoulos, Anne

“…Recently, certain chemokines and chemokine receptors have been preferentially associated with the selective recruitment in vitro of type 1 T cells, such as…”
Get full text

Characterisation of tryptase and a granzyme H-like chymase isolated from equine mastocytoma tissue by Pemberton, Alan D, McEuen, Alan R, Scudamore, Cheryl L

“…Mast cell proteinases are important inflammatory mediators in man and other species, but until now there has been no investigation of the nature of equine mast…”
Get full text