Search Results - "McEneny, Jane"

Hypoxia compounds exercise-induced free radical formation in humans; partitioning contributions from the cerebral and femoral circulation by Bailey, Damian M., Rasmussen, Peter, Evans, Kevin A., Bohm, Aske M., Zaar, Morten, Nielsen, Henning B., Brassard, Patrice, Nordsborg, Nikolai B., Homann, Pernille H., Raven, Peter B., McEneny, Jane, Young, Ian S., McCord, Joe M., Secher, Niels H.

“…This study examined to what extent the human cerebral and femoral circulation contribute to free radical formation during basal and exercise-induced responses…”
Get full text

Oxidative-Nitrosative Stress and Systemic Vascular Function in Highlanders With and Without Exaggerated Hypoxemia by Bailey, Damian M., PhD, Rimoldi, Stefano F., MD, Rexhaj, Emrush, MD, Pratali, Lorenza, MD, PhD, Salinas Salmòn, Carlos, MD, Villena, Mercedes, MD, McEneny, Jane, PhD, Young, Ian S., MD, Nicod, Pascal, MD, Allemann, Yves, MD, Scherrer, Urs, MD, Sartori, Claudio, MD

“…Background Acute exposure to high altitude stimulates free radical formation in lowlanders, yet whether this persists during chronic exposure in healthy,…”
Get full text

Competitive apnea and its effect on the human brain: focus on the redox regulation of blood‐brain barrier permeability and neuronal‐parenchymal integrity by Bain, Anthony R., Ainslie, Philip N., Hoiland, Ryan L., Barak, Otto F., Drvis, Ivan, Stembridge, Mike, MacLeod, Douglas M., McEneny, Jane, Stacey, Benjamin S., Tuaillon, Eduoard, Marchi, Nicola, De Maudave, Alexis Fayd'Herbe, Dujic, Zeljko, MacLeod, David B., Bailey, Damian M.

“…Static apnea provides a unique model that combines transient hypertension, hypercapnia, and severe hypoxemia. With apnea durations exceeding 5 min, the purpose…”
Get full text

Lycopene-rich diets modulate HDL functionality and associated inflammatory markers without affecting lipoprotein size and distribution in moderately overweight, disease-free, middle-aged adults: A randomized controlled trial by McEneny, Jane, Henry, Sarah-Louise, Woodside, Jayne, Moir, Susan, Rudd, Amelia, Vaughan, Nick, Thies, Frank

“…Background The consumption of lycopene-rich foods may lower cardiovascular disease (CVD) risk. Lycopene circulates in the blood bound to lipoproteins,…”
Get full text

Oxidant Stress in Healthy Normal-weight, Overweight, and Obese Individuals by Brown, Louise A, Kerr, Catherine J, Whiting, Paul, Finer, Nicholas, McEneny, Jane, Ashton, Tony

“…This study was undertaken to investigate the association among BMI and lipid hydroperoxide (LH), total antioxidant status (TAS), superoxide dismutase (SOD),…”
Get full text

Increased cerebral output of free radicals during hypoxia: implications for acute mountain sickness? by Bailey, Damian M, Taudorf, Sarah, Berg, Ronan M G, Lundby, Carsten, McEneny, Jane, Young, Ian S, Evans, Kevin A, James, Philip E, Shore, Angharad, Hullin, David A, McCord, Joe M, Pedersen, Bente K, Möller, Kirsten

“…This study examined whether hypoxia causes free radical-mediated disruption of the blood-brain barrier (BBB) and impaired cerebral oxidative metabolism and…”
Get more information

Sedentary aging increases resting and exercise-induced intramuscular free radical formation by BAILEY, Damian M, MCENENY, Jane, MATHIEU-COSTELLO, Odile, HENRY, Robert R, JAMES, Philip E, MCCORD, Joe M, PIETRI, Sylvia, YOUNG, Ian S, RICHARDSON, Russell S

“…Mitochondrial free radical formation has been implicated as a potential mechanism underlying degenerative senescence, although human data are lacking…”
Get full text

Lipoprotein composition in HNF1A-MODY: Differentiating between HNF1A-MODY and Type 2 diabetes by McDonald, Tim J., McEneny, Jane, Pearson, Ewan R., Thanabalasingham, Gaya, Szopa, Magdalena, Shields, Beverley M., Ellard, Sian, Owen, Katharine R., Malecki, Maciej T., Hattersley, Andrew T., Young, Ian S.

“…The young-onset diabetes seen in HNF1A-MODY is often misdiagnosed as Type 2 diabetes. Type 2 diabetes, unlike HNF1A-MODY, is associated with insulin resistance…”
Get full text

Systemic oxidative–nitrosative–inflammatory stress during acute exercise in hypoxia; implications for microvascular oxygenation and aerobic capacity by Woodside, John D. S., Gutowski, Mariusz, Fall, Lewis, James, Philip E., McEneny, Jane, Young, Ian S., Ogoh, Shigehiko, Bailey, Damian M.

“…New Findings What is the central question of this study? Exercise performance is limited during hypoxia by a critical reduction in cerebral and skeletal tissue…”
Get full text

Prognostic Value of a Multimarker Approach for Patients Presenting to Hospital With Acute Chest Pain by McCann, Conor J., MD, Glover, Ben M., MD, Menown, Ian B.A., MD, Moore, Michael J., MD, McEneny, Jane, PhD, Owens, Colum G., MD, Smith, Bernie, RGN, Sharpe, Peter C., MD, Young, Ian S., MD, Adgey, Jennifer A., MD

“…To evaluate the prognostic role of novel biomarkers for the risk stratification of patients admitted with ischemic-type chest pain, a prospective study of 664…”
Get full text

The anti-atherogenic effects of eicosapentaenoic and docosahexaenoic acid are dependent on the stage of THP-1 macrophage differentiation by McCartan, Sheila, Powell, Lesley A., Green, Brian D., McEneny, Jane, McGinty, Ann

“…•LC n-3 PUFA specific effects on initial stages of atherosclerosis.•Investigation of effects on an early and late stage macrophage differentiation…”
Get full text

High density lipoprotein subfractions: isolation, composition, and their duplicitous role in oxidation by McPherson, Peter A.C., Young, Ian S., McKibben, Bronac, McEneny, Jane

“…The plasma HDLs represent a major class of cholesterol-transporting lipoprotein that can be divided into two distinct subfractions, HDL2 and HDL3, by…”
Get full text

Regulation of free radical outflow from an isolated muscle bed in exercising humans by Bailey, Damian M, Young, Ian S, McEneny, Jane, Lawrenson, Lesley, Kim, Jeannie, Barden, Jeremy, Richardson, Russell S

“…Incremental knee extensor (KE) exercise performed at 25, 70, and 100% of single-leg maximal work rate (WR(MAX)) was combined with ex vivo electron paramagnetic…”
Get more information

Type 2 Diabetes in Young Females Results in Increased Serum Amyloid A and Changes to Features of High Density Lipoproteins in Both HDL2 and HDL3 by McKay, Gareth, McEneny, Jane, Maxwell, Alexander P., McGowan, Anne, Ahmed, Mohammed, Pazderska, Agnieszka, Griffiths, Kayleigh, Gibney, J.

“…Persons with type 2 diabetes mellitus (T2DM) have an elevated risk of atherosclerosis. High-density lipoproteins (HDL) normally protect against cardiovascular…”
Get full text

Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance by McNeilly, Andrea M, Davison, Gareth W, Murphy, Marie H, Nadeem, Nida, Trinick, Tom, Duly, Ellie, Novials, Anna, McEneny, Jane

“…Obese subjects with impaired glucose tolerance (IGT) are more susceptible than healthy individuals to oxidative stress and cardiovascular disease. This…”
Get full text

Exercise training and impaired glucose tolerance in obese humans by McNeilly, Andrea Margaret, McClean, Conor, Murphy, Marie, McEneny, Jane, Trinick, Tom, Burke, George, Duly, Ellie, McLaughlin, James, Davison, Gareth

“…Individuals with impaired glucose tolerance (IGT) are at greater risk of developing diabetes than in normoglycaemia. The aim of this study was to examine the…”
Get full text

A curvilinear approach to the kinetic analysis of linoleate peroxidation in aqueous liposomes by 2,2′azobis(2-amidoinopropane) dihydrochloride by McPherson, Peter A.C., Bole, Amanda, Cruz, Kenneth A., Young, Ian S., McEneny, Jane

“…► We investigated the application of three sigmoid functions to lipid peroxidation. ► Results demonstrate that the five-parameter Richards’ function best…”
Get full text

Primary biliary cirrhosis is associated with oxidative stress and endothelial dysfunction but not increased cardiovascular risk by Cash, William J., McCance, David R., Young, Ian S., McEneny, Jane, Cadden, Ian S., McDougall, Neil I., Callender, Michael E.

“…Aim:  Primary biliary cirrhosis (PBC) is a chronic cholestatic disease which is associated with hypercholesterolaemia. Further, cholestatic diseases are…”
Get full text

A Cross-Sectional Study Demonstrating Increased Serum Amyloid A Related Inflammation in High-Density Lipoproteins from Subjects with Type 1 Diabetes Mellitus and How This Association Was Augmented by Poor Glycaemic Control by Gibney, J., Stevenson, Michael, Moore, Kevin, Gunness, Anjuli, McGowan, Anne, Daniels, Jane-Ann, McEneny, Jane, Young, I. S.

“…Inflammatory atherosclerosis is increased in subjects with type 1 diabetes mellitus (T1DM). Normally high-density lipoproteins (HDL) protect against…”
Get full text

Vitamin C prophylaxis promotes oxidative lipid damage during surgical ischemia–reperfusion by Bailey, Damian M., Raman, Sudarsanam, McEneny, Jane, Young, Ian S., Parham, Kelly L., Hullin, David A., Davies, Bruce, McKeeman, Gareth, McCord, Joe M., Lewis, Michael H.

“…Reactive oxygen species (ROS) have been implicated in the cellular membrane damage and postoperative morbidity associated with obligatory ischemia–reperfusion…”
Get full text