Search Results - "McElhinny, Charles J"

Hydrolytic instability of the important orexin 1 receptor antagonist SB-334867: Possible confounding effects on in vivo and in vitro studies by McElhinny, Charles J., Lewin, Anita H., Mascarella, S. Wayne, Runyon, Scott, Brieaddy, Lawrence, Carroll, F. Ivy

“…SB-334867 has been an important ligand for the study of the orexin 1 (OX1) receptor due to its high OX1/OX2 selectivity and bioavailability. This ligand…”
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Novel Synthesis and Pharmacological Characterization of NOP Receptor Agonist 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (Ro 64-6198) by Chang, Steven D, Brieaddy, Lawrence E, Harvey, Joseph D, Lewin, Anita H, Mascarella, S. Wayne, Seltzman, Herbert H, Reddy, P. Anantha, Decker, Ann M, McElhinny, Charles J, Zhong, Desong, Peterson, Elisha E, Navarro, Hernán A, Bruchas, Michael R, Carroll, F. Ivy

“…The nociceptin/orphanin FQ opioid peptide (NOP) receptor is a widely expressed GPCR involved in the modulation of pain, anxiety, and motor behaviors…”
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α-[Amino(4-aminophenyl)thio]methylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solution by McElhinny, Charles J., Lewin, Anita H., Brieaddy, Larry, Fix, Scott, Imler, Gregory H., Deschamps, Jeffrey, Mascarella, S. Wayne, Seltzman, Herbert H., Anantha Reddy, P., Carroll, F. Ivy

“…The solubility and configurational composition (Z/E) of SL 327, the only systemically administered MEK inhibitor, in physiologically relevant media has been…”
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High specific activity (+)-amphetamine and (+)-methamphetamine by Lamb, Pamela B., McElhinny, Charles J., Sninski, Todd, Purdom, Hunter, Carroll, F. Ivy, Lewin, Anita H.

“…High specific activity (+)‐amphetamine and (+)‐methamphetamine were prepared by reductive dechlorination of (S)‐(3′,5′‐dichlorophenyl)‐2‐propylazide and…”
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α-Amino(4-aminophenyl)thiomethylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solution by McElhinny, Charles J, Lewin, Anita H, Brieaddy, Larry, Fix, Scott, Imler, Gregory H, Deschamps, Jeffrey, Mascarella, S Wayne, Seltzman, Herbert H, Anantha Reddy, P, Carroll, F Ivy

“…Inconsistent results have been reported for the effects of the mitogen-activating extracellular kinase (MEK) inhibitor…”
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Stereospecific synthesis of amphetamines by Wagner, Jared M., McElhinny, Charles J., Lewin, Anita H., Carroll, F.Ivy

“…Regioselective addition of aryl lithium to commercially available ( S)-(+)-propylene oxide provides the corresponding ( S)-aryl-2-propanol. The (…”
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