Search Results - "McEachern, K"

Analysis of the effects of cigarette smoke on staphylococcal virulence phenotypes by McEachern, Elisa K, Hwang, John H, Sladewski, Katherine M, Nicatia, Shari, Dewitz, Carola, Mathew, Denzil P, Nizet, Victor, Crotty Alexander, Laura E

“…Cigarette smoking is the leading preventable cause of death, disease, and disability worldwide. It is well established that cigarette smoke provokes…”
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Preliminary safety, efficacy, and PK/PD characterization from GARNET, a phase I clinical trial of the anti–PD-1 monoclonal antibody, TSR-042, in patients with recurrent or advanced MSI-H endometrial cancer by Oaknin, A., Ellard, S.L., Leath III, C., Moreno, V., Kristeleit, R., Guo, W., Lu, S., Jenkins, D., McEachern, K., Yu Jen, K., Dunlap, S., Im, E., Gilbert, L.

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536 Determining the Likelihood of Achieving Clinical Proof-of-Mechanism (PoM) with AZD1208 From Preclinical Efficacy Studies Using PK/PD Modelling by Gibbons, F, McEachern, K, Keeton, E, Huszar, D

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Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function by Crotty Alexander, Laura E., Akong-Moore, Kathryn, Feldstein, Stephanie, Johansson, Per, Nguyen, Anh, McEachern, Elisa K., Nicatia, Shari, Cowburn, Andrew S., Olson, Joshua, Cho, Jae Youn, Isaacs, Hart, Johnson, Randall S., Broide, David H., Nizet, Victor

“…Hypoxia-inducible factor (HIF)-1α is a master regulator of inflammatory activities of myeloid cells, including neutrophils and macrophages. These studies…”
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488 A Combination of Surrogate and Tumor Biopsy Biomarker Data Demonstrates JAK Pathway Inhibition by AZD1480 in Phase I Patient Samples by McCoon, P, Eder, J.P, Huszar, D, McEachern, K, Schroeder, P, Tang, W, Womack, C, Kang, Y.K, Eckhardt, S.G

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Cigarette Smoke Exposure Promotes Virulence of Pseudomonas aeruginosa and Induces Resistance to Neutrophil Killing by Chien, Jason, Hwang, John H, Nilaad, Sedtavut, Masso-Silva, Jorge A, Jeong Ahn, Sae, McEachern, Elisa K, Moshensky, Alexander, Byun, Min-Kwang, Crotty Alexander, Laura E

“…It is widely known that cigarette smoke damages host defenses and increases susceptibility to bacterial infections. , a Gram-negative bacterium that commonly…”
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Evaluation of Ecological Risk to Populations of a Threatened Plant from an Invasive Biocontrol Insect by Louda, S. M., Rand, T. A., Arnett, A. E., A. S. Mc Clay, Shea, K., A. K. Mc Eachern

“…Controversy exists over estimation of ecological risk in biological control. At present, the risk to the rare, federally listed Pitcher's thistle (Cirsium…”
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Uncertainty in Georeferencing Current and Historic Plant Locations by McEachern, Kathryn, Niessen, Ken

“…With shrinking habitats, weed invasions, and climate change, repeated surveys are becoming increasingly important for rare plant conservation and ecological…”
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1096 The PARP14 inhibitor RBN-3143 suppresses skin inflammation in preclinical models by Niepel, M., Vasbinder, M., Kunii, K., Bin, G., Mateer, E., Coutts, C., Kuplast-Barr, K., Kaur, H., Novak, J., Blackwell, D., Perl, N., Molina, J.R., Schenkel, L.B., Swinger, K., McEachern, K., Bozon, V., Richardson, C.T., Beck, L., Parasuraman, S., Kuntz, K., Keilhack, H.

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The epidemiology of notified genital Chlamydia trachomatis infection in Victoria, Australia: a survey of diagnosing providers by Thompson, S C, McEachern, K A, Stevenson, E M, Forsyth, J R

“…Data on 259 notified cases of genital chlamydia infection diagnosed in Victoria Australia in January and February 1995 were augmented by call-back. Risk factor…”
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935PDPreliminary safety, efficacy, and PK/PD characterization from GARNET, a phase I clinical trial of the anti-PD-1 monoclonal antibody, TSR-042, in patients with recurrent or advanced MSI-H endometrial cancer by Oaknin, A, Ellard, S L, Leath III, C, Moreno, V, Kristeleit, R, Guo, W, Lu, S, Jenkins, D, McEachern, K, Yu Jen, K, Dunlap, S, Im, E, Gilbert, L

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Safety, pharmacodynamic, and pharmacokinetic profile of TSR-042, an anti–PD–1 monoclonal antibody, in patients (pts) with advanced solid tumors by Sachdev, J.C., Patnaik, A., Waypa, J., Pelusi, J., Beeram, M., Im, E., Jenkins, D., McEachern, K., Lu, S., Guo, W., Tran, R., Reichert, V., Bobilev, D., Kansra, V., Weiss, G.J.

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27O First-in-class first-in-human phase I trial of RBN-2397 in patients with advanced solid tumors validates PARP7 as a novel anticancer therapeutic target by Yap, T.A., Cervantes, A., Falchook, G., Patel, M., Juric, D., Waqar, S.N., Schenk, E., Shapiro, G., Boni, V., Perez, C.A., Burtness, B., Najjar, Y., Racca, F.E., Rojas Laimito, K.I., Kuplast-Barr, K., McEachern, K., Samant, M., Bozón, V., Parasuraman, S., Johnson, M.L.

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Seasonal timing of first rain storms affects rare plant population dynamics by Levine, Jonathan M, McEachern, A. Kathryn, Cowan, Clark

“…A major challenge in forecasting the ecological consequences of climate change is understanding the relative importance of changes to mean conditions vs…”
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Do competitors modulate rare plant response to precipitation change? by Levine, Jonathan M, McEachern, A. Kathryn, Cowan, Clark

“…Ecologists increasingly suspect that climate change will directly impact species physiology, demography, and phenology, but also indirectly affect these…”
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A110 LATE BREAKING ABSTRACTS IN DISEASE SUSCEPTIBILITY AND PATHOGENESIS: Cigarette Smoke Exposure Increases Pseudomonas AerugINOSa Resistance To Neutrophil Killing Via Resistance To Reactive Oxygen Species by Hwang, H K, Sladewski, K, McEachern, E K, Enany, S, Nizet, V, Crotty Alexander, L E

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B33 GRANULOCYTE ACTIVATION IN LUNG DISEASE: Hypoxia Inducible Factor (hif)-2[alpha] In Myeloid Cells Promotes Allergic Inflammatory Airways Disease Pathogenesis In Mice by Dewitz, C, Nicatia, S, McEachern, E K, Rojas, I, Johnson, R, Nizet, V, Alexander, L E Crotty

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C16 IMMUNITY PATHWAYS IN THE LUNG: Cigarette Smoke Exposure Increases Methicillin-Resistant Staphylococcus Aureus (mrsa) Virulence Via Resistance To Antimicrobial Peptides And Oxygen Species Whereas Exposure To E-Cigarette Vapor Increases Mrsa Virulence Via Alterations In Ph by Sladewski, K, McEachern, E K, Dewitz, C, Hwang, H, Bigby, T D, Nizet, V, Alexander, L E Crotty

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Politics in the journal? by McEachern, K D

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Climate alters response of an endemic island plant to removal of invasive herbivores by McEachern, A. Kathryn, Thomson, Diane M, Chess, Katherine A

“…Islands experience higher rates of species extinction than mainland ecosystems, with biological invasions among the leading causes; they also serve as…”
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