Influenza Outbreak in a Vaccinated Population — USS Ardent, February 2014

On February 10, 2014, the USS Ardent, a U.S. Navy minesweeper, was moored in San Diego, California, while conducting training. Over the course of 3 days, 25 of 102 crew members sought medical care because of influenza-like illness (ILI). Nasal swab specimens were collected from each patient, and ini...

Full description

Saved in:

Bibliographic Details
Published in:	MMWR. Morbidity and mortality weekly report Vol. 63; no. 42; pp. 947 - 949
Main Authors:	Aquino, Theodore L., Brice, Gary T., Hayes, Sherry, Myers, Christopher A., McDowell, Jaqueline, White, Brenda, Garten, Rebecca, Johnston, Daniel
Format:	Journal Article Newsletter
Language:	English
Published:	United States Center for Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services 24-10-2014 U.S. Government Printing Office U.S. Center for Disease Control U.S. Centers for Disease Control
Subjects:	Adult California - epidemiology Contact Tracing Disease control Disease outbreaks Disease Outbreaks - prevention & control Epidemics H3N2 subtype influenza A virus Humans Influenza Influenza A virus Influenza A Virus, H3N2 Subtype - isolation & purification Influenza vaccines Influenza Vaccines - administration & dosage Influenza, Human - epidemiology Influenza, Human - prevention & control Influenza, Human - virology Male Military Military personnel Military Personnel - statistics & numerical data Navies Outbreaks Ships Specimens Symptoms Vaccination Viruses Warships Young Adult California United States > US San Diego California
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	On February 10, 2014, the USS Ardent, a U.S. Navy minesweeper, was moored in San Diego, California, while conducting training. Over the course of 3 days, 25 of 102 crew members sought medical care because of influenza-like illness (ILI). Nasal swab specimens were collected from each patient, and initial rapid influenza testing indicated 16 cases of influenza A. Ultimately, polymerase chain reaction (PCR) testing conducted by the Naval Health Research Center determined that 20 specimens were influenza A, of which 18 were subtype H3N2. Two specimens could not be subtyped. The HA gene sequence of an outbreak isolate was 99% identical to strains circulating during the 2013-14 influenza season and antigenically similar to the H3N2 component of the 2013-14 influenza vaccine. At the time of the outbreak, 99% of the crew had received influenza vaccine. Through the duration of the outbreak, the minesweeper squadron medical officer collaborated with Navy Environmental and Preventive Medicine Unit Five, higher-level Navy authorities, and County of San Diego Public Health Services to implement the outbreak response, which included disseminating outbreak information to surrounding Navy units, disinfecting the ship, sending home infected crew members, identifying family members at high risk, and providing antiviral medications and guidance. No crew member had onset of symptoms >6 days after the first crew member became ill. This outbreak highlights the risk for an H3N2 influenza outbreak among vaccinated and otherwise healthy young persons.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0149-2195 1545-861X