Search Results - "McDowell, Colin T"

Applications and continued evolution of glycan imaging mass spectrometry by McDowell, Colin T., Lu, Xiaowei, Mehta, Anand S., Angel, Peggi M., Drake, Richard R.

“…Glycosylation is an important posttranslational modifier of proteins and lipid conjugates critical for the stability and function of these macromolecules…”
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Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen–Defined Pancreatic Cancer Tissues by McDowell, Colin T., Klamer, Zachary, Hall, Johnathan, West, Connor A., Wisniewski, Luke, Powers, Thomas W., Angel, Peggi M., Mehta, Anand S., Lewin, David N., Haab, Brian B., Drake, Richard R.

“…The early detection of pancreatic ductal adenocarcinoma (PDAC) is a complex clinical obstacle yet is key to improving the overall likelihood of patient…”
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Bioorthogonal Chemical Labeling Probes Targeting Sialic Acid Isomers for N‑Glycan MALDI Imaging Mass Spectrometry of Tissues, Cells, and Biofluids by Lu, Xiaowei, McDowell, Colin T., Blaschke, Calvin R. K., Liu, Liping, Grimsley, Grace, Wisniewski, Luke, Gao, ChongFeng, Mehta, Anand S., Haab, Brian B., Angel, Peggi M., Drake, Richard R.

“…Sialic acid isomers attached in either α2,3 or α2,6 linkage to glycan termini confer distinct chemical, biological, and pathological properties, but they…”
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An N-glycome tissue atlas of 15 human normal and cancer tissue types determined by MALDI-imaging mass spectrometry by Wallace, Elizabeth N., West, Connor A., McDowell, Colin T., Lu, Xiaowei, Bruner, Evelyn, Mehta, Anand S., Aoki-Kinoshita, Kiyoko F., Angel, Peggi M., Drake, Richard R.

“…N- glycosylation is an abundant post-translational modification of most cell-surface proteins. N- glycans play a crucial role in cellular functions like…”
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Use of a Novel Whole Blood Separation and Transport Device for Targeted and Untargeted Proteomics by McDowell, Colin T, Weaver, Amanda L, Vargas-Cruz, Nylev, Kaiser, Nathan K, Nichols, Charles M, Pestano, Gary A

“…There is significant interest in developing alternatives to traditional blood transportation and separation methods, which often require centrifugation and…”
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Molecular and translational biology of the blood-based VeriStrat® proteomic test used in cancer immunotherapy treatment guidance by Koc, Matthew A, Wiles, Timothy Aaron, Weinhold, Daniel C, Rightmyer, Steven, Weaver, Amanda L, McDowell, Colin T, Roder, Joanna, Asmellash, Senait, Pestano, Gary A, Roder, Heinrich, Georgantas Iii, Robert W

“…The VeriStrat® test (VS) is a blood-based assay that predicts a patient's response to therapy by analyzing eight features in a spectrum obtained from…”
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Development of an Antibody-Based Platform for the Analysis of Immune Cell-Specific N‑linked Glycosylation by Dressman, James W., McDowell, Colin T., Lu, Xiaowei, Angel, Peggi M., Drake, Richard R., Mehta, Anand S.

“…N-linked glycosylation plays an important role in both the innate and adaptive immune response through the modulation of cell surface receptors as well as…”
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Glycan Imaging Mass Spectrometry: Progress in Developing Clinical Diagnostic Assays for Tissues, Biofluids, and Cells by Blaschke, Calvin R K, McDowell, Colin T, Black, Alyson P, Mehta, Anand S, Angel, Peggi M, Drake, Richard R

“…N-glycan imaging mass spectrometry (IMS) can rapidly and reproducibly identify changes in disease-associated N-linked glycosylation that are linked with…”
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Glycan Imaging Mass Spectrometry by Blaschke, Calvin R.K., McDowell, Colin T., Black, Alyson P., Mehta, Anand S., Angel, Peggi M., Drake, Richard R.

“…N-glycan imaging mass spectrometry (IMS) can rapidly and reproducibly identify changes in disease-associated N-linked glycosylation that are linked with…”
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Imaging Mass Spectrometry and Lectin Analysis of N-linked Glycans in Carbohydrate Antigen Defined Pancreatic Cancer Tissues by McDowell, Colin T, Klamer, Zachary, Hall, Johnathan, West, Connor A, Wisniewski, Luke, Powers, Thomas W, Angel, Peggi, Mehta, Anand S, Lewin, David N, Haab, Brian, Drake, Richard

“…The early detection of pancreatic ductal adenocarcinoma is a complex clinical obstacle yet is key to improving the overall likelihood of patient survival…”
Get full text