Search Results - "McDougal, Owen"

Accessible high-throughput virtual screening molecular docking software for students and educators by Jacob, Reed B, Andersen, Tim, McDougal, Owen M

“…We survey low cost high-throughput virtual screening (HTVS) computer programs for instructors who wish to demonstrate molecular docking in their courses. Since…”
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Veratrum parviflorum : An Underexplored Source for Bioactive Steroidal Alkaloids by Seale, Jared T, McDougal, Owen M

“…Plants of the genus have been used throughout history for their emetic properties, rheumatism, and for the treatment of high blood pressure. However,…”
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2023 journal summary from Editor in Chief by McDougal, Owen M.

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Biomedical rationale for acrylamide regulation and methods of detection by Cantrell, Maranda S., McDougal, Owen M.

“…Acrylamide is the product of the Maillard reaction, which occurs when starchy, asparagine‐rich foods including potato or grain products and coffee are fried,…”
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Pharmacology of Veratrum californicum Alkaloids as Hedgehog Pathway Antagonists by Dirks, Madison L, McDougal, Owen M

“…contains steroidal alkaloids that function as inhibitors of hedgehog (Hh) signaling, a pathway involved in the growth and differentiation of cells and normal…”
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Review: Veratrum californicum Alkaloids by Dirks, Madison L, Seale, Jared T, Collins, Joseph M, McDougal, Owen M

“…spp. grow throughout the world and are especially prevalent in high mountain meadows of North America. All parts of plants have been used for the treatment of…”
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Whey Protein Powder Analysis by Mid-Infrared Spectroscopy by Saxton, Rose, McDougal, Owen M

“…There is an ever-expanding number of high protein dietary supplements marketed as beneficial to athletes, body builders, infant formulas, elder care, and…”
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Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death by Pinkaew, Decha, Chattopadhyay, Abhijnan, King, Matthew D., Chunhacha, Preedakorn, Liu, Zhihe, Stevenson, Heather L., Chen, Yanjie, Sinthujaroen, Patuma, McDougal, Owen M., Fujise, Ken

“…The endoplasmic reticulum, the cytoplasmic organelle that matures a massive amount of nascent secretory polypeptides, is particularly sensitive to stress…”
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Native V. californicum Alkaloid Combinations Induce Differential Inhibition of Sonic Hedgehog Signaling by Turner, Matthew W, Cruz, Roberto, Elwell, Jordan, French, John, Mattos, Jared, McDougal, Owen M

“…is a rich source of steroidal alkaloids such as cyclopamine, a known inhibitor of the Hedgehog (Hh) signaling pathway. Here we provide a detailed analysis of…”
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Integration of Video-Based Demonstrations to Prepare Students for the Organic Chemistry Laboratory by Nadelson, Louis S., Scaggs, Jonathan, Sheffield, Colin, McDougal, Owen M.

“…Consistent, high-quality introductions to organic chemistry laboratory techniques effectively and efficiently support student learning in the organic chemistry…”
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GAMPMS: Genetic algorithm managed peptide mutant screening by Long, Thomas, McDougal, Owen M., Andersen, Tim

“…The prominence of endogenous peptide ligands targeted to receptors makes peptides with the desired binding activity good molecular scaffolds for drug…”
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SPIDR: small-molecule peptide-influenced drug repurposing by King, Matthew D, Long, Thomas, Pfalmer, Daniel L, Andersen, Timothy L, McDougal, Owen M

“…Conventional de novo drug design is costly and time consuming, making it accessible to only the best resourced research organizations. An emergent approach to…”
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Genetic Algorithm Managed Peptide Mutant Screening: Optimizing Peptide Ligands for Targeted Receptor Binding by King, Matthew D, Long, Thomas, Andersen, Timothy, McDougal, Owen M

“…This study demonstrates the utility of genetic algorithms to search exceptionally large and otherwise intractable mutant libraries for sequences with optimal…”
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Medicinal history of North American Veratrum by Chandler, Christopher M, McDougal, Owen M

“…Plants belonging to the genus Veratrum have been used throughout history for their medicinal properties. During the nineteenth and twentieth centuries,…”
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The M-superfamily of conotoxins: a review by Jacob, Reed B., McDougal, Owen M.

“…The focus of this review is the M-superfamily of Conus venom peptides. Disulfide rich peptides belonging to the M-superfamily have three loop regions and the…”
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Mutagenesis of α-Conotoxins for Enhancing Activity and Selectivity for Nicotinic Acetylcholine Receptors by Turner, Matthew W, Marquart, Leanna A, Phillips, Paul D, McDougal, Owen M

“…Nicotinic acetylcholine receptors (nAChRs) are found throughout the mammalian body and have been studied extensively because of their implication in a myriad…”
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Qualitative Assay to Detect Dopamine Release by Ligand Action on Nicotinic Acetylcholine Receptors by Marquart, Leanna A, Turner, Matthew W, McDougal, Owen M

“…A pheochromocytoma of the rat adrenal medulla derived (a.k.a. PC12) cell-based assay for dopamine measurement by luminescence detection was customized for the…”
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Expression and purification of a cleavable recombinant fortilin from Escherichia coli for structure activity studies by Cantrell, Maranda S., Wall, Jackson D., Pu, Xinzhu, Turner, Matthew, Woodbury, Luke, Fujise, Ken, McDougal, Owen M., Warner, Lisa R.

“…Complications related to atherosclerosis account for approximately 1 in 4 deaths in the United States and treatment has focused on lowering serum…”
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SVR Chemometrics to Quantify β-Lactoglobulin and α-Lactalbumin in Milk Using MIR by Babatunde, Habeeb Abolaji, Collins, Joseph, Lukman, Rianat, Saxton, Rose, Andersen, Timothy, McDougal, Owen M

“…Protein content variation in milk can impact the quality and consistency of dairy products, necessitating access to in-line real time monitoring. Here, we…”
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Oncostatin M binds to extracellular matrix in a bioactive conformation: Implications for inflammation and metastasis by Ryan, Randall E., Martin, Bryan, Mellor, Liliana, Jacob, Reed B., Tawara, Ken, McDougal, Owen M., Oxford, Julia Thom, Jorcyk, Cheryl L.

“…Model for OSM role in chronic inflammation and tumor metastasis. Inflammatory cells infiltrate into a particular microenvironment and secrete OSM, which binds…”
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