Search Results - "McDonnell, G.V"

Evidence for the role of demyelination, HLA-DR alleles, and cytokines in the pathogenesis of parvovirus B19 meningoencephalitis and its sequelae by Kerr, J R, Barah, F, Chiswick, M L, McDonnell, G V, Smith, J, Chapman, M D, Bingham, J B, Kelleher, P, Sheppard, M N

“…Objective: To review the clinical and pathological features of parvovirus B19 meningoencephalitis and its sequelae in 12 previously published cases, and to…”
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Primary progressive multiple sclerosis: increasing clarity but many unanswered questions by McDonnell, G.V, Hawkins, S.A

“…Heterogeneity in the clinical course of multiple sclerosis (MS) is well recognised and patients following a primary progressive course, 10–15% of the MS…”
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An assessment of the spectrum of disability and handicap in multiple sclerosis: a population-based study by McDonnell, G.V., Hawkins, S.A.

“…To establish the spectrum of disability and handicap in a population based sample of multiple sclerosis (MS) patients. Much knowledge exists about the…”
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A study of the HLA-DR region in clinical subgroups of multiple sclerosis and its influence on prognosis by McDonnell, G.V., Mawhinney, H., Graham, C.A., Hawkins, S.A., Middleton, D.

“…Objective: To investigate the HLA-DR associations in relapsing-remitting/secondary progressive multiple sclerosis (RR/SPMS) and primary progressive MS (PPMS)…”
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CD80 (B7-1) and CD86 (B7-2) expression in multiple sclerosis patients by Boylan, M.T, Crockard, A.D, McDonnell, G.V, Armstrong, M.A, Hawkins, S.A

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An evaluation of interleukin genes fails to identify clear susceptibility loci for multiple sclerosis by McDonnell, G.V, Kirk, C.W, Hawkins, S.A, Graham, C.A

“…Differential expression of interleukins may influence susceptibility to inflammatory diseases such as MS. IL-1a production is increased in MS patients during…”
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Cerebrospinal fluid (CSF) indices of inflammatory markers across the clinical spectrum of multiple sclerosis (MS) by McMillan, S.A., McDonnell, G.V., Douglas, J.P., Hawkins, S.A.

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Lack of association of transforming growth factor (TGF)-β1 and β2 gene polymorphisms with multiple sclerosis (MS) in Northern Ireland by McDonnell, G.V., Kirk, C.W., Hawkins, S.A., Graham, C.A.

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A bad dose of 'flu by McDonnell, G V

“…Three days into his current illness he had attended his general practitioner and been prescribed ibuprofen, aspirin, and a "cold remedy". Investigations at…”
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Raised CSF levels of soluble adhesion molecules across the clinical spectrum of multiple sclerosis by McDonnell, G.V, McMillan, S.A, Douglas, J.P, Droogan, A.G, Hawkins, S.A

“…Endothelial activation is considered an important step in multiple sclerosis (MS) lesion formation, elevated cerebrospinal fluid (CSF) and serum levels of…”
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Serum and cerebrospinal fluid soluble Fas levels in clinical subgroups of multiple sclerosis by Boylan, M.T, Crockard, A.D, McDonnell, G.V, McMillan, S.A, Hawkins, S.A

“…Elevated sFas levels have been described in multiple sclerosis (MS) patients with active disease. The aim of this study was to assess the diagnostic potential…”
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CD80 (B7-1) and CD86 (B7-2) expression in multiple sclerosis patients:: clinical subtype specific variation in peripheral monocytes and B cells and lack of modulation by high dose methylprednisolone by Boylan, M.T, Crockard, A.D, McDonnell, G.V, Armstrong, M.A, Hawkins, S.A

“…Autoimmune activation of T cells by central nervous system (CNS)-derived antigens is hypothesised to underlie neural damage in multiple sclerosis (MS)…”
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An Unusual Case of Ataxia by Murtagh, E., McDonnell, G.V, Hawkins, S.A., McKinstry, C.S.

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Relationship between tumour necrosis factor-alpha (TNFα) production and a specific multiple sclerosis (MS) associated TNF gene haplotype by Armstrong, M.A., McDonnell, G.V., Graham, C.A., Kirk, C.W., Droogan, A.G., Hawkins, S.A.

“…To determine if monocyte TNFalpha production from patients homozygous for a specific MS associated TNF gene haplotype is different from that produced in…”
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A neurological evaluation of adult phenylketonuria in Northern Ireland by McDonnell, G V, Esmonde, T F, Hadden, D R, Morrow, J I

“…To investigate the extent of neurological disease in adults with phenylketonuria and also their requirement for specialist medical services, we assessed 27…”
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An audit of the new antiepileptic drugs in clinical neurological practice by McDonnell, G.V., Morrow, J.I.

“…Three new antiepileptic drugs (AEDs) are finding increasing use in medical practice. To examine their efficacy and side-effect profile, 483 patients with…”
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