Search Results - "McDonnell, G V"

Benign multiple sclerosis? Clinical course, long term follow up, and assessment of prognostic factors by Hawkins, S A, McDonnell, G V

“…OBJECTIVE To establish the characteristics of patients following a benign course of multiple sclerosis and evaluate the importance of potential prognostic…”
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Multiple sclerosis severity score : Using disability and disease duration to rate disease severity by ROXBURGH, R. H. S. R, SEAMAN, S. R, EDAN, G, MCDONNELL, G. V, HAWKINS, S, TROJANO, M, LIGUORI, M, COCCO, E, MARROSU, M. G, TESSER, F, LEONE, M. A, WEBER, A, MASTERMAN, T, ZIPP, F, MITERSKI, B, EPPLEN, J. T, OTURAI, A, SOELBERG SØRENSEN, P, CELIUS, E. G, TELLEZ LARA, N, MONTALBAN, X, VILLOSLADA, P, SILVA, A. M, HENSIEK, A. E, MARTA, M, LEITE, I, DUBOIS, B, RUBIO, J, BUTZKUEVEN, H, KILPATRICK, T, MYCKO, M. P, SELMAJ, K. W, RIO, M. E, SA, M, SAWCER, S. J, SALEMI, G, SAVETTIERI, G, HILLERT, J, COMPSTON, D. A. S, VUKUSIC, S, ACHITI, I, CONFAVREUX, C, COUSTANS, M, LE PAGE, E

“…There is no consensus method for determining progression of disability in patients with multiple sclerosis (MS) when each patient has had only a single…”
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Tried and tested: the psychometric properties of the multiple sclerosis impact scale (MSIS-29) in a population-based study by Gray, OM, McDonnell, GV, Hawkins, SA

“…Objective To investigate the psychometric properties of the Multiple Sclerosis Impact Scale (MSIS-29) and to assess the relationship between the Kurtzke…”
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Factors in the rising prevalence of multiple sclerosis in the north-east of Ireland by Gray, OM, McDonnell, GV, Hawkins, SA

“…Background Northern Ireland is recognized as an area of high risk for multiple sclerosis. The original study of Allison and Millar in 1951 found a prevalence…”
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OPSOCLONUS-MYOCLONUS SYNDROME ASSOCIATED WITH BENIGN OVARIAN TERATOMA by FITZPATRICK, A. S, GRAY, O. M, MCCONVILLE, J, MCDONNELL, G. V

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Transient cardiomyopathy as the presenting feature of acute disseminated encephalomyelitis by Mawhinney, E., Watt, M., McDonnell, GV

“…Brainstem lesions are rarely associated with neurogenic pulmonary oedema (NPO) in multiple sclerosis and other disorders. The exact mechanism for this is…”
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Evidence for the role of demyelination, HLA-DR alleles, and cytokines in the pathogenesis of parvovirus B19 meningoencephalitis and its sequelae by Kerr, J R, Barah, F, Chiswick, M L, McDonnell, G V, Smith, J, Chapman, M D, Bingham, J B, Kelleher, P, Sheppard, M N

“…Objective: To review the clinical and pathological features of parvovirus B19 meningoencephalitis and its sequelae in 12 previously published cases, and to…”
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A rare characteristic neuroimaging pattern in hyperammonaemia by Kinney, M O, McDonnell, G V, McConville, J, McCarron, M O, McKenna, E

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An epidemiologic study of multiple sclerosis in Northern Ireland by MCDONNELL, G. V, HAWKINS, S. A

“…We wanted to establish the point prevalence of MS in Northern Ireland. Northern Ireland has been a known high-risk area for MS since the original work of…”
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Issues of medical management in adults with spina bifida by MCDONNELL, G. V, MCCANN, J. P

“…The objective of this study was to establish the range of medical issues among those attending a clinic for adults with spina bifida (SB) and hydrocephalus…”
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A systematic review of oral methotrexate for multiple sclerosis by Gray, O M, McDonnell, G V, Forbes, R B

“…Oral methotrexate is a potent immunosuppressant, which could have a beneficial effect on relapse rates and delay disease progression in multiple sclerosis…”
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Primary progressive multiple sclerosis: increasing clarity but many unanswered questions by McDonnell, G.V, Hawkins, S.A

“…Heterogeneity in the clinical course of multiple sclerosis (MS) is well recognised and patients following a primary progressive course, 10–15% of the MS…”
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An investigation of susceptibility loci in benign, aggressive and primary progressive multiple sclerosis in Northern Irish population by Gray, OM, Abdeen, H, McDonnell, GV, Patterson, CC, Graham, CA, Hawkins, SA

“…Objective To investigate the possibility that susceptibility loci in multiple sclerosis (MS) have a role in determining the disease outcome in Northern Ireland…”
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Clinical study of primary progressive multiple sclerosis in Northern Ireland, UK by McDonnell, G V, Hawkins, S A

“…OBJECTIVE To investigate the clinical and demographic characteristics of primary progressive multiple sclerosis (PPMS) in Northern Ireland and to establish a…”
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Clinical presentation of primary progressive multiple sclerosis 10 years after the incidental finding of typical magnetic resonance imaging brain lesions: The subclinical stage of primary progressive multiple sclerosis may last 10 years by McDonnell, G V, Cabrera-Gomez, J, Calne, D B, Li, D KB, Oger, J

“…Background: Subclinical multiple sclerosis (MS) has been identified incidentally at autopsy; apparently unaffected individuals with an affected twin have…”
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A study of the HLA-DR region in clinical subgroups of multiple sclerosis and its influence on prognosis by McDonnell, G.V., Mawhinney, H., Graham, C.A., Hawkins, S.A., Middleton, D.

“…Objective: To investigate the HLA-DR associations in relapsing-remitting/secondary progressive multiple sclerosis (RR/SPMS) and primary progressive MS (PPMS)…”
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094  Measuring neutralising antibodies (NAbs) to interferon-beta (IFNB) for multiple sclerosis (MS): a neglected practice? by McKee, JD, Spence, RW, Hughes, S, Gray, O, Campbell, J, Droogan, A, McDonnell, GV

“…ObjectiveTo determine frequency of testing for NAbs to IFNB in our MS population and adherence to international (EFNS) guidelines.BackgroundIFNB was the first…”
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An assessment of the spectrum of disability and handicap in multiple sclerosis: a population-based study by McDonnell, G.V., Hawkins, S.A.

“…To establish the spectrum of disability and handicap in a population based sample of multiple sclerosis (MS) patients. Much knowledge exists about the…”
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Serum soluble adhesion molecules in multiple sclerosis : raised sVCAM-1, sICAM-1 and sE-selectin in primary progressive disease by MCDONNELL, G. V, MCMILLAN, S. A, DOUGLAS, J. P, DROOGAN, A. G, HAWKINS, S. A

“…Leucocyte invasion into the central nervous system in multiple sclerosis (MS) is complex, involving T-cell/endothelium interaction dependent upon initial…”
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An evaluation of interleukin genes fails to identify clear susceptibility loci for multiple sclerosis by McDonnell, G.V, Kirk, C.W, Hawkins, S.A, Graham, C.A

“…Differential expression of interleukins may influence susceptibility to inflammatory diseases such as MS. IL-1a production is increased in MS patients during…”
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