Search Results - "McDonald, Tyler R"
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Selective Carbon-Carbon Bond Cleavage of Cyclopropanols
Published in Chemical reviews (13-01-2021)“…The carbon-carbon (C-C) bond cleavage of cyclopropanols is a wide area of research with much current activity. This review highlights new developments in this…”
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Journal Article -
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Synthesis of Borylated (Aminomethyl)cyclopropanes Using C 1 -Bisnucleophiles
Published in Organic letters (10-05-2024)“…Lithiated 1,1-diborylalkanes have been used as nucleophilic coupling partners with a range of oxygen-based electrophiles, including esters, carbonyls, and…”
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Journal Article -
3
Synthesis of 3-borylated cyclobutanols from epihalohydrins or epoxy alcohol derivatives
Published in Chemical science (Cambridge) (25-01-2023)“…There is an increasing interest in cyclobutanes within the medicinal chemistry community. Therefore, methods to prepare cyclobutanes that contain synthetic…”
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Journal Article -
4
Synthesis of Borylated (Aminomethyl)cyclopropanes Using C1–Bisnucleophiles
Published in Organic letters (10-05-2024)“…Lithiated 1,1-diborylalkanes have been used as nucleophilic coupling partners with a range of oxygen-based electrophiles, including esters, carbonyls, and…”
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Journal Article -
5
Synthesis of Chiral Spin-Labeled Amino Acids
Published in Organic letters (20-12-2019)“…Spin-labeled amino acids (SLAAs) are often used to determine intermolecular distances and conformations in proteins via double electron–electron resonance…”
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Journal Article -
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Synthesis of trans-2-Substituted Cyclopropylamines from α‑Chloroaldehydes
Published in Organic letters (18-10-2019)“…Cyclopropylamines are prevalent in pharmaceuticals and agrochemicals. Herein, we report the synthesis of trans-2-substituted cyclopropylamines in high…”
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Journal Article -
7
Synthesis of Small Carbocycles using C1-Bisnucleophiles
Published 01-01-2024“…This thesis describes novel methods for the synthesis of 3- and 4-membered carbocycles using C1- bisnucleophiles. These approaches represent new strategies for…”
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Dissertation