Search Results - "McDonald, Melanie"

Oncogenic STAT Transcription Factors as Targets for Cancer Therapy: Innovative Strategies and Clinical Translation by Wang, Weiyuan, Lopez McDonald, Melanie Cristina, Hariprasad, Rajashree, Hamilton, Tiara, Frank, David A

“…Despite advances in our understanding of molecular aspects of oncogenesis, cancer remains a leading cause of death. The malignant behavior of a cancer cell is…”
Get full text

The complementary roles of STAT3 and STAT1 in cancer biology: insights into tumor pathogenesis and therapeutic strategies by Wang, Weiyuan, Lopez McDonald, Melanie Cristina, Kim, Christine, Ma, Mirielle, Pan, Zetao Tommy, Kaufmann, Charlotte, Frank, David A

“…STATs are a family of transcription factors that regulate many critical cellular processes such as proliferation, apoptosis, and differentiation. Dysregulation…”
Get full text

Dynamic Response Systems of Healthcare Mask Production to COVID-19: A Case Study of Korea by Lee, EunSu, Chen, Yi-Yu, McDonald, Melanie, O’Neill, Erin

“…Korea initiated a new experiment, called a dynamic response system for open democratic societies as a principle to respond to the novel coronavirus (COVID-19)…”
Get full text

Predicting Oil Production Sites for Planning Road Infrastructure: Trip Generation Using SIR Epidemic Model by Lee, EunSu, Chakraborty, Debananda, McDonald, Melanie

“…Drilling activity produces a significant amount of road traffic through unpaved and paved local roads. Because oil production is an important contributor to…”
Get full text

At the Heart of It All: Emotions of Consequence for the Conceptualization of Caregiver-Reported Outcomes in the Context of Colorectal Cancer by Howard, A. Fuchsia, Lynch, Kelsey, Beck, Scott, Torrejón, Maria-José, Avery, Jonathan, Thorne, Sally, Porcino, Antony, De Vera, Mary, Lambert, Leah, Wolff, Angela, McDonald, Melanie, Lee, Joyce, Hedges, Penelope, McKenzie, Michael

“…Colorectal cancer (CRC) can be demanding for primary caregivers; yet, there is insufficient evidence describing the caregiver-reported outcomes (CROs) that…”
Get full text

Cycloguanil and Analogues Potently Target DHFR in Cancer Cells to Elicit Anti-Cancer Activity by Brown, Jennifer I, Wang, Peng, Wong, Alan Y L, Petrova, Boryana, Persaud, Rosanne, Soukhtehzari, Sepideh, Lopez McDonald, Melanie, Hanke, Danielle, Christensen, Josephine, Iliev, Petar, Wang, Weiyuan, Everton, Daniel K, Williams, Karla C, Frank, David A, Kanarek, Naama, Page, Brent D G

“…Dihydrofolate reductase (DHFR) is an established anti-cancer drug target whose inhibition disrupts folate metabolism and STAT3-dependent gene expression…”
Get full text

To share or not to share: communication of caregiver-reported outcomes when a patient has colorectal cancer by Howard, A. Fuchsia, Torrejón, María-José, Lynch, Kelsey, Beck, Scott M., Thorne, Sally, Lambert, Leah, Porcino, Antony, De Vera, Mary A., Davies, Janine M., Avery, Jonathan, Wolff, Angela C., McDonald, Melanie, Lee, Joyce W. K., Hedges, Penelope, Kelly, Mary T., McKenzie, Michael

“…Background The importance of patient-centered measurement in cancer care has led to recognition of the potential for caregiver-reported outcomes to improve…”
Get full text

How do I work with fertility loss as a pregnant therapist? A case study and discussion about pregnancy self-disclosure in the oncology setting by McDonald, Melanie, Rappaport, Amy, Bates, Alan

Get full text

Statewide Ambulance Coverage of a Mixed Region of Urban, Rural and Frontier under Travel Time Catchment Areas by Lee, EunSu, McDonald, Melanie, O'Neill, Erin, Montgomery, William

“…This study examines the statewide service coverage of emergency medical services (EMS) in view of public health planners, policy makers, and ambulance service…”
Get full text

Emotional distress and psychosocial needs in patients with breast cancer in British Columbia: younger versus older adults by Naik, Hiten, Leung, Bonnie, Laskin, Janessa, McDonald, Melanie, Srikanthan, Amirrtha, Wu, Jonn, Bates, Alan, Ho, Cheryl

“…Purpose This study evaluates the prevalence of emotional distress and psychosocial needs in young adult (YA, age 18–39) patients at the time of their breast…”
Get full text

Use of an Integrated Functional Quantitation of Modulation of Transcriptional Pathways (IFQ) Assay in Untreated Mantle Cell Lymphoma Patients by Gerber, Drew, Lopez-McDonald, Melanie, Wang, Weiyuan, Koff, Jean L., Churnetski, Michael, O'Leary, Colin B, Cohen, Jonathon B., Frank, David A.

“…Background: Mantle cell lymphoma (MCL) is an extremely heterogenous cancer, with substantial variation in clinical presentation and genetic makeup among…”
Get full text

Spatial key performance indicators on the statewide ambulance service coverage of multiple regional classifications by Lee, EunSu, McDonald, Melanie, Montgomery, William, O’Neill, Erin

“…The total population covered by the current ambulance service under threshold response time and policy is one of the major concerns for policymakers and…”
Get full text

Increased 1-year continuation of DMPA among women randomized to self-administration: results from a randomized controlled trial at Planned Parenthood by Kohn, Julia E., Simons, Hannah R., Della Badia, Lisa, Draper, Elissa, Morfesis, Johanna, Talmont, Elizabeth, Beasley, Anitra, McDonald, Melanie, Westhoff, Carolyn L.

“…Self-administration of subcutaneous depot medroxyprogesterone acetate (DMPA-sc) is feasible, acceptable, and effective. Our objective was to compare one-year…”
Get full text

Addressing Oncofertility Needs: Views of Female Cancer Patients in Fertility Preservation by Yee, Samantha, Abrol, Kaajal, McDonald, Melanie, Tonelli, Madeline, Liu, Kimberly E.

“…A total of 41 questionnaires were returned from 64 respondents who consented to receive a questionnaire through the mail. Almost all valued the opportunity to…”
Get full text

Yoga for Health-Related Quality of Life in Adult Cancer: A Randomized Controlled Feasibility Study by Ward, Alison, Thorne, Sally, McDonald, Melanie, McCall, Marcy C., Heneghan, Carl

“…An increase in patient-led uptake of complementary therapies in adult cancer has led to a need for more rigorous study of such interventions and their…”
Get full text

Fostering Community Collaborations Using a Job Search/Résumé Writing Series by Blau-McDonald, Melanie

“…  Outreach is a process that takes time and repetition. One's customers have to get to know his program offerings--that they can trust him to give them good…”
Get full text

Spread the Word: Creating a Consumer Protection Series by Blau-McDonald, Melanie

Get full text

Spread the Word: Volunteering Resources by Blau-McDonald, Melanie A

Get full text

Spread the Word: Back to School = Outreach to Teachers or Education Majors by Blau-McDonald, Melanie

Get full text

Increased 1-Year Continuation of DMPA Among Women Randomized to Self-administration: Results From a Randomized Controlled Trial at Planned Parenthood by Kohn, Julia E, Simons, Hannah R, Badia, Lisa Della, Draper, Elissa, Morfesis, Johanna, Talmont, Elizabeth, Beasley, Anitra, McDonald, Melanie, Westhoff, Carolyn L

“…(Abstracted from Contraception 2018;97:198–204)Consistent use of effective contraception is the most effective way to reduce unintended pregnancy…”
Get full text