Search Results - "McDermott, J B"
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Intermedin (adrenomedullin‐2): a novel counter‐regulatory peptide in the cardiovascular and renal systems
Published in British journal of pharmacology (01-03-2008)“…Intermedin (IMD) is a novel peptide related to calcitonin gene‐related peptide (CGRP) and adrenomedullin (AM). Proteolytic processing of a larger precursor…”
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Dietary fish oil augments nitric oxide production or release in patients with type 2 (non-insulin-dependent) diabetes mellitus
Published in Diabetologia (1993)“…Decreased release of nitric oxide from damaged endothelium is responsible for the impaired endothelium-dependent vasodilator responses found in animal models…”
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Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus
Published in Diabetologia (01-08-1992)Get full text
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NPY and cardiac diseases
Published in Current topics in medicinal chemistry (01-01-2007)“…Hypertension-induced left ventricular hypertrophy (LVH), along with ischemic heart disease, result in LV remodeling as part of a continuum that often leads to…”
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Cardiovascular effects of neuropeptide Y: receptor interactions and cellular mechanisms
Published in Cardiovascular research (01-06-1993)Get more information
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In Situ Stimulation of Aerobic PCB Biodegradation in Hudson River Sediments
Published in Science (American Association for the Advancement of Science) (22-01-1993)“…A 73-day field study of in situ aerobic biodegradation of polychlorinated biphenyls (PCBs) in the Hudson River shows that indigenous aerobic microorganisms can…”
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A comparison of enalapril 20 mg once daily versus 10 mg twice daily in terms of blood pressure lowering and patient compliance
Published in Journal of hypertension (01-11-1999)“…To compare enalapril 20 mg once daily with 10 mg twice daily in terms of blood pressure reduction and patient compliance. Cross-over study of patients randomly…”
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Neuropeptide Y stimulates hypertrophy of adult ventricular cardiomyocytes
Published in The American journal of physiology (01-05-1994)“…It was investigated whether neuropeptide Y (NPY) could exert a trophic effect on ventricular myocytes isolated from the adult rat heart. Two different culture…”
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Regulation of protein synthesis and degradation in adult ventricular cardiomyocytes
Published in The American journal of physiology (01-12-1995)“…For studies on the regulation of myocardial protein metabolism, isolated adult cardiomyocytes were introduced as an experimental model about a decade ago. When…”
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Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene
Published in Proceedings of the National Academy of Sciences - PNAS (09-05-1995)“…The abundance of delta-crystallin in the chicken eye lens provides an advantageous marker for tissue-specific gene expression during cellular differentiation…”
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Endothelin(A) receptor subtype mediates endothelin-induced contractility in left ventricular cardiomyocytes isolated from rabbit myocardium
Published in The Journal of pharmacology and experimental therapeutics (01-09-2000)“…Endothelin (ET)-1 is a potent positive inotropic agent, the effects of which are mediated by increases in cytosolic Ca(2+) in the myocardium. The object of…”
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Inotropic response to endothelin‐1, isoprenaline and calcium in cardiomyocytes isolated from endotoxin treated rats: effects of ethyl‐isothiourea and dexamethasone
Published in British journal of pharmacology (01-07-2000)“…The contractile effects of endothelin‐1, isoprenaline and extracellular calcium were assessed on ventricular cardiomyocytes isolated from…”
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Troglitazone does not initiate hypertrophy but can sensitise cardiomyocytes to growth effects of serum
Published in European journal of pharmacology (03-03-2000)“…Chronic administration of troglitazone might predispose to cardiac hypertrophy. The aims of the study were to determine if troglitazone could (i) initiate a…”
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Positive and negative contractile effects of neuropeptide Y on ventricular cardiomyocytes
Published in The American journal of physiology (01-12-1991)“…The potency of neuropeptide Y (NPY) to cause negative and positive contractile responses in rat ventricular cardiomyocytes was investigated. In these cells,…”
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Calcitonin gene-related peptide stimulates a positive contractile response in rat ventricular cardiomyocytes
Published in Journal of cardiovascular pharmacology (01-06-1994)“…Calcitonin gene-related peptide (CGRP) elicits marked positive inotropic and chronotropic actions in the atria of several mammals. The second-messenger…”
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Endothelin‐1 mediated inhibition of the acetylcholine‐activated potassium current from rabbit isolated atrial cardiomyocytes
Published in British journal of pharmacology (01-12-1996)“…1 Endothelin‐1 is a 21 amino acid peptide with potent inotropic and chronotropic actions in the heart. Relatively little is known about the underlying…”
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Cardiotonic actions of selective phosphodiesterase inhibitors in rat isolated ventricular cardiomyocytes
Published in British journal of pharmacology (01-12-1993)“…1 The contractile effects of the novel cardiotonic agent HN‐10200 (2‐[3‐methoxy‐5‐methylsulphinyl‐2‐thienyl]‐1H‐imidazo‐[4,5‐c]‐pyridine hydrochloride), were…”
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A complex enhancer of the chicken beta A3/A1-crystallin gene depends on an AP-1-CRE element for activity
Published in Investigative ophthalmology & visual science (01-04-1997)“…To define transcriptional regulatory elements of the chicken beta A3/A1-crystallin gene. Reporter genes were made with fragments of the chicken beta…”
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SB-271258, A major metabolite in the dog of the thiazolidinedione, rosiglitazone, stimulates protein synthesis in re-differentiated rat cardiomyocytes in vitro
Published in Toxicology in vitro (01-09-2006)“…In dogs, chronic administration of thiazolidinediones causes cardiac hypertrophy in vivo at high doses. The hypertrophic action of rosiglitazone in dogs might…”
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