Search Results - "McDaniel, Elizabeth C."
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The Elusive 5′-Deoxyadenosyl Radical: Captured and Characterized by Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopies
Published in Journal of the American Chemical Society (31-07-2019)“…The 5′-deoxyadenosyl radical (5′-dAdo·) abstracts a substrate H atom as the first step in radical-based transformations catalyzed by…”
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Paradigm Shift for Radical S‑Adenosyl‑l‑methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis
Published in Journal of the American Chemical Society (18-07-2018)“…Radical S-adenosyl-l-methionine (SAM) enzymes comprise a vast superfamily catalyzing diverse reactions essential to all life through homolytic SAM cleavage to…”
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The B12-independent glycerol dehydratase activating enzyme from Clostridium butyricum cleaves SAM to produce 5′-deoxyadenosine and not 5′-deoxy-5′-(methylthio)adenosine
Published in Journal of inorganic biochemistry (01-02-2022)“…Glycerol dehydratase activating enzyme (GD-AE) is a radical S-adenosyl-l-methionine (SAM) enzyme that installs a catalytically essential amino acid backbone…”
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Mechanistic Studies of Radical SAM Enzymes: Pyruvate Formate-Lyase Activating Enzyme and Lysine 2,3-Aminomutase Case Studies
Published in Methods in enzymology (2018)“…The radical SAM enzyme superfamily is large and diverse, with ever-increasing numbers of examples of characterized reactions. This chapter focuses on the…”
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Active-Site Controlled, Jahn-Teller Enabled Regioselectivity in Reductive S-C Bond Cleavage of S -Adenosylmethionine in Radical SAM Enzymes
Published in Journal of the American Chemical Society (13-01-2021)“…Catalysis by canonical radical -adenosyl-l-methionine (SAM) enzymes involves electron transfer (ET) from [4Fe-4S] to SAM, generating an R S radical that…”
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HydG, the "dangler" iron, and catalytic production of free CO and CN - : implications for [FeFe]-hydrogenase maturation
Published in Dalton transactions : an international journal of inorganic chemistry (04-08-2021)“…The organometallic H-cluster of the [FeFe]-hydrogenase consists of a [4Fe-4S] cubane bridged via a cysteinyl thiolate to a 2Fe subcluster ([2Fe]H) containing…”
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Measuring and increasing silent reading comprehension rates: Empirically validating a repeated readings intervention
Published in Psychology in the schools (01-09-2000)“…The current study was designed to demonstrate how researchers could use a direct measure of functional reading skills (e.g., rates of silent reading…”
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An Investigation of Situational Bias: Conspicuous and Covert Timing during Curriculum-Based Measurement of Mathematics across African American and Caucasian Students
Published in School psychology review (01-12-2002)“…Evaluates situational bias that could be associated with curriculum-based measurement (CBM). During CBM, students are timed while responding. Results showed…”
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The B 12 -independent glycerol dehydratase activating enzyme from Clostridium butyricum cleaves SAM to produce 5'-deoxyadenosine and not 5'-deoxy-5'-(methylthio)adenosine
Published in Journal of inorganic biochemistry (01-02-2022)“…Glycerol dehydratase activating enzyme (GD-AE) is a radical S-adenosyl-l-methionine (SAM) enzyme that installs a catalytically essential amino acid backbone…”
Get full text
Journal Article