Search Results - "McCue, Peter"
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1
Deep Weird: The Varieties of High Strangeness Experience
Published in Journal of scientific exploration (09-04-2024)Get full text
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GATA3: A Multispecific But Potentially Useful Marker in Surgical Pathology: A Systematic Analysis of 2500 Epithelial and Nonepithelial Tumors
Published in The American journal of surgical pathology (01-01-2014)“…GATA3 is a transcription factor important in the differentiation of breast epithelia, urothelia, and subsets of T lymphocytes. It has been suggested to be…”
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Comprehensive Immunohistochemical Study of Programmed Cell Death Ligand 1 (PD-L1): Analysis in 5536 Cases Revealed Consistent Expression in Trophoblastic Tumors
Published in The American journal of surgical pathology (01-08-2016)“…Programmed cell death 1/programmed cell death ligand (PD-1/PD-Ls) axis is crucial for the modulation of immune responses and self-tolerance. Also, aberrant…”
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Sox10—A Marker for Not Only Schwannian and Melanocytic Neoplasms But Also Myoepithelial Cell Tumors of Soft Tissue: A Systematic Analysis of 5134 Tumors
Published in The American journal of surgical pathology (01-06-2015)“…Sox10 transcription factor is expressed in schwannian and melanocytic lineages and is important in their development and can be used as a marker for…”
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5
Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets
Published in Nature communications (09-04-2015)“…Pancreatic ductal adenocarcinoma (PDA) has a dismal prognosis and insights into both disease etiology and targeted intervention are needed. A total of 109…”
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SALL4 Expression in Germ Cell and Non–Germ Cell Tumors: A Systematic Immunohistochemical Study of 3215 Cases
Published in The American journal of surgical pathology (01-03-2014)“…The SALL4 transcription factor is associated with embryonic cell pluripotency and has been shown as a useful immunohistochemical marker for germ cell tumors…”
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Transplant glomerulopathy
Published in Modern pathology (01-02-2018)“…In the renal allograft, transplant glomerulopathy represents a morphologic lesion and not a specific diagnosis. The hallmark pathologic feature is glomerular…”
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Immunologic and Metabolic Features of Pancreatic Ductal Adenocarcinoma Define Prognostic Subtypes of Disease
Published in Clinical cancer research (15-07-2016)“…Pancreatic ductal adenocarcinoma (PDA) is associated with an immunosuppressive microenvironment that supports the growth of the malignancy as well as immune…”
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Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma
Published in Cancer research (Chicago, Ill.) (01-07-2015)“…Uveal melanoma patients with metastatic disease usually die within one year, emphasizing an urgent need to develop new treatment strategies for this cancer…”
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10
microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling
Published in Proceedings of the National Academy of Sciences - PNAS (04-05-2010)“…microRNAs are thought to regulate tumor progression and invasion via direct interaction with target genes within cells. Here the microRNA17/20 cluster is shown…”
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Genomic Prostate Cancer Classifier Predicts Biochemical Failure and Metastases in Patients After Postoperative Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-08-2014)“…Purpose To test the hypothesis that a genomic classifier (GC) would predict biochemical failure (BF) and distant metastasis (DM) in men receiving radiation…”
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FOXD3 Regulates VISTA Expression in Melanoma
Published in Cell reports (Cambridge) (14-01-2020)“…Immune checkpoint inhibitors have improved patient survival in melanoma, but the innate resistance of many patients necessitates the investigation of…”
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RB/E2F1 as a Master Regulator of Cancer Cell Metabolism in Advanced Disease
Published in Cancer discovery (01-09-2021)“…Loss of the retinoblastoma (RB) tumor suppressor protein is a critical step in reprogramming biological networks that drive cancer progression, although…”
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Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017
Published in Journal of clinical oncology (01-02-2018)“…Purpose Guidelines are limited for genetic testing for prostate cancer (PCA). The goal of this conference was to develop an expert consensus-driven working…”
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Composite analysis of immunological and metabolic markers defines novel subtypes of triple negative breast cancer
Published in Modern pathology (01-02-2018)“…Cancer biology is influenced by the tumor microenvironment, which impacts disease prognosis and therapeutic interventions. The inter-relationship of…”
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Sarcomatoid renal cell tumor harboring a novel BYSL::TFEB fusion with concurrent TFEB amplification
Published in Genes chromosomes & cancer (01-06-2023)“…Transcription factor EB (TFEB)‐rearranged renal cell carcinoma (RCC) exhibits diverse gene fusion patterns and heterogeneous clinicopathologic features. Rare…”
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A Cyclin D1/microRNA 17/20 Regulatory Feedback Loop in Control of Breast Cancer Cell Proliferation
Published in The Journal of cell biology (11-08-2008)“…Decreased expression of specific microRNAs (miRNAs) occurs in human tumors, which suggests a function for miRNAs in tumor suppression. Herein, levels of the…”
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The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module
Published in Cancer research (Chicago, Ill.) (15-05-2015)“…Prostate cancer is the second leading form of cancer-related death in men. In a subset of prostate cancer patients, increased chemokine signaling IL8 and IL6…”
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MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies
Published in Cell reports (Cambridge) (24-12-2014)“…KRAS mutation, which occurs in ∼95% of pancreatic ductal adenocarcinoma (PDA), has been shown to program tumor metabolism. MCT4 is highly upregulated in a…”
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ErbB3 Targeting Enhances the Effects of MEK Inhibitor in Wild-Type BRAF/NRAS Melanoma
Published in Cancer research (Chicago, Ill.) (01-10-2018)“…MEK-ERK1/2 signaling is elevated in melanomas that are wild-type for both BRAF and NRAS (WT/WT), but patients are insensitive to MEK inhibitors…”
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