Search Results - "McCudden, Christopher"

Deus Ex Machina? Predicting SARS-CoV-2 Infection from Lab Tests Using Machine Learning by McCudden, Christopher R

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Cerebrospinal Fluid Total Protein Reference Intervals Derived from 20 Years of Patient Data by McCudden, Christopher R, Brooks, John, Figurado, Priya, Bourque, Pierre R

“…Reference intervals are vital for interpretation of laboratory results. Many existing reference intervals for cerebrospinal fluid total protein (CSF-TP) are…”
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Validating, Implementing, and Monitoring Machine Learning Solutions in the Clinical Laboratory Safely and Effectively by Spies, Nicholas C, Farnsworth, Christopher W, Wheeler, Sarah, McCudden, Christopher R

“…Machine learning solutions offer tremendous promise for improving clinical and laboratory operations in pathology. Proof-of-concept descriptions of these…”
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Adult CSF total protein upper reference limits should be age-partitioned and significantly higher than 0.45 g/L: a systematic review by Breiner, Ari, Moher, David, Brooks, John, Cheng, Wei, Hegen, Harald, Deisenhammer, Florian, McCudden, Christopher R., Bourque, Pierre R.

“…Background Cerebrospinal fluid total protein (CSF-TP) is measured in the diagnosis of a range of immune or infectious disorders of the nervous system. Most…”
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Characterizing ability of serum potassium (K) and the serum K reference interval to flag hypokalemia or hyperkalemia as observed in plasma: A simulation study by Stickle, Douglas F., Koob, K. Rebecca, McCudden, Christopher R.

“…•Serum K, positively shifted from plasma K, contains a component due to clotting.•We simulated a serum distribution for K from an observed plasma K…”
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Recognition and management of common, rare, and novel serum protein electrophoresis and immunofixation interferences by McCudden, Christopher R., Jacobs, Joannes F.M., Keren, David, Caillon, Hélène, Dejoie, Thomas, Andersen, Kristian

“…Protein electrophoresis and immunofixation are subject to a variety of analytical interferences that may affect monoclonal protein diagnostics performed in the…”
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Adult CSF total protein: Higher upper reference limits should be considered worldwide. A web-based survey by Bourque, Pierre R, Breiner, Ari, Moher, David, Brooks, John, Hegen, Harald, Deisenhammer, Florian, McCudden, Christopher R

“…AbstractBackgroundThe cerebrospinal fluid total protein level (CSF-TP) is commonly used as a potential marker of infectious or immune disease of the CNS and…”
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Monoclonal protein reference change value as determined by gel-based serum protein electrophoresis by Salamatmanesh, Mina, McCudden, Christopher R., McCurdy, Arleigh, Booth, Ronald A.

“…The International Myeloma Working Group recommendations for monitoring disease progression or response include quantitation of the involved monoclonal…”
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Selection of Single-Analyte Delta Check Rules with Logistic Regression for Detection of Intravenous Fluid Contamination in a Clinical Chemistry Laboratory by Yang, Jianbo, Wen, Sijin, McCudden, Christopher R, Tacker, Danyel H

“…Abstract Background The conventional single-analyte delta check, utilized for identifying intravenous fluid contamination and other preanalytical errors, is…”
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Robustness of the Reichert Unistat Bilirubinometer for analysis of hemolyzed samples from neonates by McCudden, Christopher R., Fleming, Kathy, Warr, Michelle

“…•The objective of this study was to determine the effect of hemolysis on bilirubin measurement in neonates.•Based on the Bhutani nomogram, 1/70 samples would…”
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Quality, origins and limitations of common therapeutic drug reference intervals by McCudden, Christopher R

“…Therapeutic drug monitoring (TDM) is used to manage drugs with a narrow window between effective and toxic concentrations. TDM involves measuring blood…”
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Limited Evidence for Use of a Black Race Modifier in eGFR Calculations: A Systematic Review by Marzinke, Mark A, Greene, Dina N, Bossuyt, Patrick M, Chambliss, Allison B, Cirrincione, Lauren R, McCudden, Christopher R, Melanson, Stacy E F, Noguez, Jaime H, Patel, Khushbu, Radix, Asa E, Takwoingi, Yemisi, Winston-McPherson, Gabrielle, Young, Bessie A, Hoenig, Melanie P

“…Abstract Background Commonly used estimated glomerular filtration rate (eGFR) equations include a Black race modifier (BRM) that was incorporated during…”
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An international multi-center serum protein electrophoresis accuracy and M-protein isotyping study. Part I: factors impacting limit of quantitation of serum protein electrophoresis by Turner, Katherine A, Frinack, Jody L, Ettore, Michael W, Tate, Jillian R, Graziani, Maria Stella, Jacobs, Joannes F M, Booth, Ronald A, McCudden, Christopher R, Keren, David F, Delgado, Julio C, Zemtsovskaja, Galina, Fullinfaw, Robert O, Caldini, Anna, de Malmanche, Theo, Katakouzinos, Katina, Burke, Matthew, Palladini, Giovanni, Altinier, Sara, Zaninotto, Martina, Righetti, Gabriella, Melki, Marie Therese, Bell, Stephen, Willrich, Maria Alice Vieira

“…Background Serum protein electrophoresis (SPEP) is used to quantify the serum monoclonal component or M-protein, for diagnosis and monitoring of monoclonal…”
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An international multi-center serum protein electrophoresis accuracy and M-protein isotyping study. Part II: limit of detection and follow-up of patients with small M-proteins by Jacobs, Joannes F M, Turner, Katherine A, Graziani, Maria Stella, Frinack, Jody L, Ettore, Michael W, Tate, Jillian R, Booth, Ronald A, McCudden, Christopher R, Keren, David F, Delgado, Julio C, Zemtsovskaja, Galina, Fullinfaw, Robert O, Caldini, Anna, de Malmanche, Theo, Katakouzinos, Katina, Burke, Matthew, Palladini, Giovanni, Altinier, Sara, Zaninotto, Martina, Righetti, Gabriella, Melki, Marie Therese, Bell, Stephen, Willrich, Maria Alice Vieira

“…Background Electrophoretic methods to detect, characterize and quantify M-proteins play an important role in the management of patients with monoclonal…”
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Continuous reference intervals for pediatric testosterone, sex hormone binding globulin and free testosterone using quantile regression by Holmes, Daniel T., van der Gugten, J Grace, Jung, Benjamin, McCudden, Christopher R.

“…Testosterone (T), sex hormone binding globulin (SHBG), free testosterone (FT) and bioavailable testosterone (BAT) are commonly employed tests in pediatric…”
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Reproducible manuscript preparation with RMarkdown application to JMSACL and other Elsevier Journals by Holmes, Daniel T., Mobini, Mahdi, McCudden, Christopher R.

“…With the rising complexity of modern multimarker analytical techniques and notable scientific publication retractions required for erroneous statistical…”
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Candidate recommendations for protein electrophoresis reporting from the Canadian Society of Clinical Chemists Monoclonal Gammopathy Working Group by Booth, Ronald A., McCudden, Christopher R., Balion, Cynthia M., Blasutig, Ivan M., Bouhtiauy, Ihssan, Rodriguez-Capote, Karina, Catomeris, Peter, Chan, Pak Cheung, Chen, Yu, Collier, Christine, Hauff, Kristin, Kalra, Jawahar, Li, Dailin, Lin, Dan C., Lou, Amy H., Meng, Qing H., Morrison, Tracy, Pasic, Maria D., Qureshi, Mabood, Randell, Ed, Sohn, Kun-Young, Thakur, Vinita, Thomas, Dylan, Thoni, Andrea, Tomalty, Cheryl, Yang, Liju, Zamkanei, Mohebullah

“…Protein electrophoresis is commonly used as an aid in the diagnosis of monoclonal gammopathies and is performed in many laboratories in Canada and throughout…”
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Editorial on laboratory diagnosis and management of plasma cell dyscrasias special issue by Keren, David F., McCudden, Christopher R., Booth, Ronald A.

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Does Diabetes Alter CSF Total Protein Levels? A Retrospective Cohort Study by Breiner, Ari, Bourque, Pierre R., Warman-Chardon, Jodi, Brooks, John, McCudden, Christopher R.

“…Background and Purpose: Elevation of total protein level in cerebrospinal fluid (CSF-TP) in diabetic patients is often disregarded by clinicians. However,…”
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Synoptic reporting for protein electrophoresis and immunofixation by McCudden, Christopher R., Booth, Ronald A., Lin, Danny C.C., McCurdy, Arleigh, Rupani, Natasha, Kew, Andrea

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