Search Results - "McCrory, Mark A"

Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses by Wende, Adam R, Kim, Jaetaek, Holland, William L, Wayment, Benjamin E, O'Neill, Brian T, Tuinei, Joseph, Brahma, Manoja K, Pepin, Mark E, McCrory, Mark A, Luptak, Ivan, Halade, Ganesh V, Litwin, Sheldon E, Abel, E Dale

“…Pathological cardiac hypertrophy may be associated with reduced expression of glucose transporter 4 (GLUT4) in contrast to exercise-induced cardiac…”
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Enhanced Cardiac Akt/Protein Kinase B Signaling Contributes to Pathological Cardiac Hypertrophy in Part by Impairing Mitochondrial Function via Transcriptional Repression of Mitochondrion-Targeted Nuclear Genes by Wende, Adam R., O'Neill, Brian T., Bugger, Heiko, Riehle, Christian, Tuinei, Joseph, Buchanan, Jonathan, Tsushima, Kensuke, Wang, Li, Caro, Pilar, Guo, Aili, Sloan, Crystal, Kim, Bum Jun, Wang, Xiaohui, Pereira, Renata O., McCrory, Mark A., Nye, Brenna G., Benavides, Gloria A., Darley-Usmar, Victor M., Shioi, Tetsuo, Weimer, Bart C., Abel, E. Dale

“…Sustained Akt activation induces cardiac hypertrophy (LVH), which may lead to heart failure. This study tested the hypothesis that Akt activation contributes…”
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C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice by PAUL, Antoni, KO, Kerry W. S, LI, Lan, YECHOOR, Vijay, MCCRORY, Mark A, SZALAI, Alexander J, CHAN, Lawrence

“…Plasma C-reactive protein (CRP) concentration is a strong predictor of atherosclerosis. However, to date, there is no in vivo evidence that CRP is…”
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Human C-reactive protein impedes entry of leptin into the CNS and attenuates its physiological actions in the CNS by Li, Jie, Wei, Dong, McCrory, Mark A, Szalai, Alexander J, Yang, Gangyi, Li, Ling, Li, Fanghong, Zhao, Allan Z

“…Defective central leptin signalling and impaired leptin entry into the CNS (central nervous system) represent two important aspects of leptin resistance in…”
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C-Reactive Protein-Mediated Vascular Injury Requires Complement by Hage, Fadi G, Oparil, Suzanne, Xing, Dongqi, Chen, Yiu-Fai, McCrory, Mark A, Szalai, Alexander J

“…BACKGROUND—We previously demonstrated that vascular injury-induced neointima formation is exaggerated in human C-reactive protein (CRP) transgenic (CRPtg)…”
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Inhibiting C-Reactive Protein for the Treatment of Cardiovascular Disease: Promising Evidence from Rodent Models by Henry, Scott P., Zanardi, Thomas A., Graham, Mark J., Crooke, Rosanne M., Mazzone, Michelle, Chen, Yiu-Fai, Oparil, Suzanne, Miller, Andrew, Hage, Fadi G., Xing, Dongqi, McCrory, Mark A., Szalai, Alexander J., Early, Richard

“…Raised blood C-reactive protein (CRP) level is a predictor of cardiovascular events, but whether blood CRP is causal in the disease process is unknown. The…”
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The Virulence Function of Streptococcus pneumoniae Surface Protein A Involves Inhibition of Complement Activation and Impairment of Complement Receptor-Mediated Protection by Ren, Bing, McCrory, Mark A, Pass, Christina, Bullard, Daniel C, Ballantyne, Christie M, Xu, Yuanyuan, Briles, David E, Szalai, Alexander J

“…Complement is important for elimination of invasive microbes from the host, an action achieved largely through interaction of complement-decorated pathogens…”
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A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans by Jones, Nicholas R, Pegues, Melissa A, McCrory, Mark A, Singleton, Walter, Bethune, Claudette, Baker, Brenda F, Norris, Daniel A, Crooke, Rosanne M, Graham, Mark J, Szalai, Alexander J

“…Observational studies of patients with established rheumatoid arthritis (RA) document a positive correlation between C-reactive protein (CRP) blood…”
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Exaggerated Neointima Formation in Human C-Reactive Protein Transgenic Mice Is IgG Fc Receptor Type I (FcγRI)-Dependent by Xing, Dongqi, Hage, Fadi G, Chen, Yiu-Fai, McCrory, Mark A, Feng, Wenguang, Skibinski, Gregory A, Majid-Hassan, Erum, Oparil, Suzanne, Szalai, Alexander J

“…Neointima formation after vascular injury is exaggerated in ovariectomized (OVX) human C-reactive protein transgenic mice (CRPtg) compared to nontransgenic…”
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Hepatic but Not CNS-Expressed Human C-Reactive Protein Inhibits Experimental Autoimmune Encephalomyelitis in Transgenic Mice by Szalai, Alexander J., McCrory, Mark A., Hou, Xiaogang, Bali, Namrata, Morgan, Todd E., Jimenez, Rachel V., Wright, Tyler T., Finch, Caleb E.

“…We recently demonstrated that human C-reactive protein (CRP), expressed hepatically in transgenic mice (CRPtg), improved the outcome of experimental autoimmune…”
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C-reactive protein exacerbates renal ischemia-reperfusion injury by Pegues, Melissa A, McCrory, Mark A, Zarjou, Abolfazl, Szalai, Alexander J

“…Renal ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI), occurring with hypotension and cardiovascular surgery and inevitably…”
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Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular health by Owsley, Cynthia, Huisingh, Carrie, Jackson, Gregory R, Curcio, Christine A, Szalai, Alexander J, Dashti, Nassrin, Clark, Mark, Rookard, Kia, McCrory, Mark A, Wright, Tyler T, Callahan, Michael A, Kline, Lanning B, Witherspoon, C Douglas, McGwin, Jr, Gerald

“…Delayed rod-mediated dark adaptation (DA) is characteristic of early age-related macular degeneration (AMD) and also can be observed in some older adults in…”
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Estrogen Treatment Abrogates Neointima Formation in Human C-Reactive Protein Transgenic Mice by Wang, Dajun, Oparil, Suzanne, Chen, Yiu-Fai, McCrory, Mark A, Skibinski, Gregory A, Feng, Wenguang, Szalai, Alexander J

“…OBJECTIVE—Previously we established that the vascular injury response was attenuated in ovariectomized wild-type rodents treated with 17β-estradiol (E2). We…”
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Varied biologic functions of C-reactive protein: lessons learned from transgenic mice by Szalai, Alexander J, McCrory, Mark A

“…Our investigations of human C-reactive protein (CRP) and CRP transgenic mice have produced novel data that firmly establish this protein as an important host…”
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Induction of leptin resistance through direct interaction of C-reactive protein with leptin by Zhao, Allan Z, Chen, Ke, Li, Fanghong, Li, Ji, Cai, Hongbo, Strom, Steven, Bisello, Alessandro, Kelley, David E, Friedman-Einat, Miriam, Skibinski, Gregory A, McCrory, Mark A, Szalai, Alexander J

“…The mechanisms underlying leptin resistance are still being defined. We report here the presence in human blood of several serum leptin-interacting proteins…”
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Inhibition of Experimental Autoimmune Encephalomyelitis in Human C-Reactive Protein Transgenic Mice Is Fcγ RIIB Dependent by Hu, Xian-Zhen, Wright, Tyler T., Jones, Nicholas R., Ramos, Theresa N., Skibinski, Gregory A., McCrory, Mark A., Barnum, Scott R., Szalai, Alexander J.

“…We showed earlier that experimental autoimmune encephalomyelitis (EAE) in human C-reactive protein (CRP) transgenic mice (CRPtg) has delayed onset and reduced…”
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Collagen‐induced arthritis is exacerbated in C‐reactive protein–deficient mice by Jones, Nicholas R., Pegues, Melissa A., McCrory, Mark A., Kerr, Steven W., Jiang, Huiping, Sellati, Rosemarie, Berger, Valentina, Villalona, Jorge, Parikh, Rajvee, McFarland, Mary, Pantages, Lynn, Madwed, Jeffrey B., Szalai, Alexander J.

“…Objective Blood C‐reactive protein (CRP) is routinely measured to gauge inflammation. In rheumatoid arthritis (RA), a heightened CRP level is predictive of a…”
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Pneumococcal Surface Protein A Inhibits Complement Activation by Streptococcus pneumoniae by TU, A.-H. T, FULGHAM, R. L, MCCRORY, M. A, BRILES, D. E, SZALAI, A. J

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Regulation of Myocardial Ketone Oxidative Proteins by Increased O ‐GlcNAcylation by Brahma, Manoja K, McCrory, Mark A, Paterson, Andrew J, Pepin, Mark E, Young, Martin E, Wende, Adam R

“…Abstract only An adult heart exhibits tremendous metabolic flexibility by utilizing a variety of substrates to meet its constant fuel demand. However, this…”
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Delayed lupus onset in (NZB × NZW)F1 mice expressing a human C‐reactive protein transgene by Szalai, Alexander J., Weaver, Casey T., McCrory, Mark A., van Ginkel, Frederik W., Reiman, Rachael M., Kearney, John F., Marion, Tony N., Volanakis, John E.

“…Objective Human C‐reactive protein (CRP) binds apoptotic cells and alters blood clearance of injected chromatin in mice. To test whether CRP participates in…”
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