Search Results - "McCreath, Kenneth J"

Mitochondrial Reactive Oxygen Species Mediate Cardiomyocyte Formation from Embryonic Stem Cells in High Glucose by Crespo, Francisco Luna, Sobrado, Veronica R., Gomez, Laura, Cervera, Ana M., McCreath, Kenneth J.

“…Accumulating evidence points to reactive oxygen species (ROS) as important signaling molecules for cardiomyocyte differentiation in embryonic stem (ES) cells…”
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Inhibition of succinate dehydrogenase dysregulates histone modification in mammalian cells by Cervera, Ana M, Bayley, Jean-Pierre, Devilee, Peter, McCreath, Kenneth J

“…Remodelling of mitochondrial metabolism is a hallmark of cancer. Mutations in the genes encoding succinate dehydrogenase (SDH), a key Krebs cycle component,…”
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Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs by Dai, Yifan, Vaught, Todd D, Boone, Jeremy, Chen, Shu-Hung, Phelps, Carol J, Ball, Suyapa, Monahan, Jeff A, Jobst, Peter M, McCreath, Kenneth J, Lamborn, Ashley E, Cowell-Lucero, Jamie L, Wells, Kevin D, Colman, Alan, Polejaeva, Irina A, Ayares, David L

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Mitochondria Determine the Differentiation Potential of Cardiac Mesoangioblasts by San Martin, Nuria, Cervera, Ana M., Cordova, Claudia, Covarello, Diego, McCreath, Kenneth J., Galvez, Beatriz G.

“…An understanding of cardiac progenitor cell biology would facilitate their therapeutic potential for cardiomyocyte restoration and functional heart repair. Our…”
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Targeted disruption of the SUCNR1 metabolic receptor leads to dichotomous effects on obesity by McCreath, Kenneth J, Espada, Sandra, Gálvez, Beatriz G, Benito, Marina, de Molina, Antonio, Sepúlveda, Pilar, Cervera, Ana M

“…A number of metabolites have signaling properties by acting through G-protein-coupled receptors. Succinate, a Krebs cycle intermediate, increases after…”
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Cells silenced for SDHB expression display characteristic features of the tumor phenotype by Cervera, Ana M, Apostolova, Nadezda, Crespo, Francisco Luna, Mata, Manuel, McCreath, Kenneth J

“…Recently, enzymes of the tricarboxylic acid (TCA) cycle have emerged as novel tumor suppressors. In particular, mutations in the nuclear-encoded subunits of…”
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Conservation of IGF2-H19 and IGF2R imprinting in sheep: effects of somatic cell nuclear transfer by Young, Lorraine E., Schnieke, Angelika E., McCreath, Kenneth J., Wieckowski, Sébastien, Konfortova, Galia, Fernandes, Kenneth, Ptak, Grazyna, Kind, Alex J., Wilmut, Ian, Loi, Pasqualino, Feil, Robert

“…In different mammalian species, in vitro culture and manipulation can lead to aberrant fetal and peri-natal development. It has been postulated that these…”
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Conventional gene targeting protocols lead to loss of targeted cells when applied to a silent gene locus in primary fibroblasts by Marques, Margarita M., Thomson, Alison J., McCreath, Kenneth J., McWhir, Jim

“…Gene targeting in livestock fibroblasts has proven difficult to achieve, particularly if the target gene is silent. We first tested whether efficient gene…”
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An alternatively spliced transcript of the PHD3 gene retains prolyl hydroxylase activity by Cervera, Ana M., Apostolova, Nadezda, Luna-Crespo, Francisco, Sanjuan-Pla, Alejandra, Garcia-Bou, Remedios, McCreath, Kenneth J.

“…Cellular response to limiting oxygen levels is managed, in part, by the transcription factor hypoxia-inducible factor 1 (HIF-1), and the prolyl hydroxylase…”
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Molecular Cloning and Characterization of Chitinase Genes from Candida albicans by McCreath, Kenneth J., Specht, Charles A., Robbins, Phillips W.

“…Chitinase (EC 3.2.1.14) is an important enzyme for the remodeling of chitin in the cell wall of fungi. We have cloned three chitinase genes (CHT1, CHT2, and…”
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Molecular cloning and characterization of a Candida albicans gene coding for cytochrome c haem lyase and a cell wall‐related protein by Cervera, Ana M., Gozalbo, Daniel, McCreath, Kenneth J., Gow, Neil A. R., Martínez, José P., Casanova, Manuel

“…Immunoscreening of a Candida albicans cDNA library with a monoclonal antibody (mAb 4C12) recognizing an epitope present in high‐molecular‐weight mannoprotein…”
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A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1α by Sanjuán-Pla, Alejandra, Cervera, Ana M., Apostolova, Nadezda, Garcia-Bou, Remedios, Víctor, Víctor M., Murphy, Michael P., McCreath, Kenneth J.

“…Exposure to limiting oxygen in cells and tissues induce the stabilization and transcriptional activation of the hypoxia-inducible factor 1 alpha (HIF-1α)…”
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Recent progress in pharmacological research of antioxidants in pathological conditions: cardiovascular health by Victor, Victor M, McCreath, Kenneth J, Rocha, Milagros

“…Antioxidants are essential, and are involved in several important biological processes such as immunity, protection against tissue damage, reproduction, growth…”
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Cloning and Expression of Two Chitin Deacetylase Genes ofSaccharomyces cerevisiae by MISHRA, CHITRA, SEMINO, CARLOS E., McCREATH, KENNETH J., DE LA VEGA, HUMBERTO, JONES, BEVERLY J., SPECHT, CHARLES A., ROBBINS, PHILLIPS W.

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A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1alpha by Sanjuán-Pla, Alejandra, Cervera, Ana M, Apostolova, Nadezda, Garcia-Bou, Remedios, Víctor, Víctor M, Murphy, Michael P, McCreath, Kenneth J

“…Exposure to limiting oxygen in cells and tissues induce the stabilization and transcriptional activation of the hypoxia-inducible factor 1 alpha (HIF-1alpha)…”
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Cloning and Expression of Two Chitin Deacetylase Genes of Saccharomyces cerevisiae by MISHRA, CHITRA, SEMINO, CARLOS E., McCREATH, KENNETH J., DE LA VEGA, HUMBERTO, JONES, BEVERLY J., SPECHT, CHARLES A., ROBBINS, PHILLIPS W.

“…Chitin deacetylase (EC 3.5.1.41), which hydrolyses the N‐acetamido groups of N‐acetyl‐d‐glucosamine residues in chitin, has been demonstrated in crude extracts…”
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Targeted disruption of the [alpha]1,3-galactosyltransferase gene in cloned pigs by Dai, Yifan, Vaught, Todd D, Boone, Jeremy, Shu-Hung, Chen, Phelps, Carol J, Ball, Suyapa, Monahan, Jeff A, Jobst, Peter M, McCreath, Kenneth J, Lamborn, Ashley E, Cowell-Lucero, Jamie L, Wells, Kevin D, Colman, Alan, Polejaeva, Irina A, Ayares, David L

“…Galactose-alpha1,3-galactose (alpha1,3Gal) is the major xenoantigen causing hyperacute rejection in pig-to-human xenotransplantation. Disruption of the gene…”
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Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs by Dai, Yifan, Vaught, Todd D, Boone, Jeremy, Chen, Shu-Hung, Phelps, Carol J, Ball, Suyapa, Monahan, Jeff A, Jobst, Peter M, McCreath, Kenneth J, Lamborn, Ashley E, Cowell-Lucero, Jamie L, Wells, Kevin D, Colman, Alan, Polejaeva, Irina A, Ayares, David L

“…Galactose-alpha1,3-galactose (alpha1,3Gal) is the major xenoantigen causing hyperacute rejection in pig-to-human xenotransplantation. Disruption of the gene…”
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Molecular cloning of a third chitinase gene (CHT1) from Candida albicans by McCreath, Kenneth J., Specht, Charles A., Liu, Yilun, Robbins, Phillips W.

“…Here we report the complete nucleotide sequence of a third chitinase gene (CHT1) from the dimorphic human pathogen Candida albicans. The deduced amino acid…”
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