Search Results - "McCreath, K J"
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Production of gene-targeted sheep by nuclear transfer from cultured somatic cells
Published in Nature (London) (29-06-2000)“…It is over a decade since the first demonstration that mouse embryonic stem cells could be used to transfer a predetermined genetic modification to a whole…”
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Induction of trefoil factor (TFF)1, TFF2 and TFF3 by hypoxia is mediated by hypoxia inducible factor‐1: implications for gastric mucosal healing
Published in British journal of pharmacology (01-01-2009)“…Background and purpose: Mucosal microcirculation is compromised during gastric damage induced by non‐steroidal anti‐inflammatory drugs, such as aspirin…”
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Targeted disruption of the alpha 1, 3-galactosyltransferase gene in cloned pigs
Published in Nature biotechnology (01-03-2002)“…Galactose- alpha 1, 3-galactose ( alpha 1,3Gal) is the major xenoantigen causing hyperacute rejection in pig-to-human xenotransplantation. Disruption of the…”
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Molecular Cloning and Characterization of Chitinase Genes from Candida albicans
Published in Proceedings of the National Academy of Sciences - PNAS (28-03-1995)“…Chitinase (EC 3.2.1.14) is an important enzyme for the remodeling of chitin in the cell wall of fungi. We have cloned three chitinase genes (CHT1, CHT2, and…”
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erratum: Production of gene-targeted sheep by nuclear transfer from cultured somatic cells
Published in Nature (London) (02-11-2000)Get full text
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Cloning and Expression of Two Chitin Deacetylase Genes of Saccharomyces cerevisiae
Published in Yeast (Chichester, England) (30-03-1997)“…Chitin deacetylase (EC 3.5.1.41), which hydrolyses the N‐acetamido groups of N‐acetyl‐d‐glucosamine residues in chitin, has been demonstrated in crude extracts…”
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Conservation of IGF2-H19 and IGF2R imprinting in sheep: effects of somatic cell nuclear transfer
Published in Mechanisms of development (01-12-2003)“…In different mammalian species, in vitro culture and manipulation can lead to aberrant fetal and peri-natal development. It has been postulated that these…”
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Molecular cloning and characterization of a Candida albicans gene coding for cytochrome c haem lyase and a cell wall‐related protein
Published in Molecular microbiology (01-10-1998)“…Immunoscreening of a Candida albicans cDNA library with a monoclonal antibody (mAb 4C12) recognizing an epitope present in high‐molecular‐weight mannoprotein…”
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A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1α
Published in FEBS letters (09-05-2005)“…Exposure to limiting oxygen in cells and tissues induce the stabilization and transcriptional activation of the hypoxia-inducible factor 1 alpha (HIF-1α)…”
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An alternatively spliced transcript of the PHD3 gene retains prolyl hydroxylase activity
Published in Cancer letters (20-02-2006)“…Cellular response to limiting oxygen levels is managed, in part, by the transcription factor hypoxia-inducible factor 1 (HIF-1), and the prolyl hydroxylase…”
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Molecular cloning of a third chitinase gene (CHT1) from Candida albicans
Published in Yeast (Chichester, England) (01-04-1996)“…Here we report the complete nucleotide sequence of a third chitinase gene (CHT1) from the dimorphic human pathogen Candida albicans. The deduced amino acid…”
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Recent progress in pharmacological research of antioxidants in pathological conditions: cardiovascular health
Published in Recent patents on anti-infective drug discovery (01-01-2006)“…Antioxidants are essential, and are involved in several important biological processes such as immunity, protection against tissue damage, reproduction, growth…”
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