Search Results - "McCrea, William"
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Time to TAVI: streamlining the pathway to treatment
Published in Open heart (04-09-2023)“…IntroductionSevere aortic stenosis is a major cause of morbidity and mortality. The existing treatment pathway for transcatheter aortic valve implantation…”
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Tetralogy of Fallot in a 78-Year-Old Man
Published in The New England journal of medicine (13-09-2007)“…A 78-year-old man was admitted to the hospital after an episode of unexplained syncope. Cardiac MRI was consistent with a diagnosis of balanced, uncorrected…”
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Implementation of NICE clinical guideline 95 on chest pain of recent onset: experience in a district general hospital
Published in Clinical medicine (London, England) (01-06-2015)“…The National Institute for Health and Care Excellence (NICE) CG95 clinical guideline on chest pain of recent onset was published in 2010. There is debate over…”
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Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma
Published in ACS medicinal chemistry letters (10-09-2015)“…Abrogation of errant signaling along the MAPK pathway through the inhibition of B-RAF kinase is a validated approach for the treatment of pathway-dependent…”
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Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors
Published in Journal of medicinal chemistry (22-01-2009)“…The inhibition of key receptor tyrosine kinases (RTKs) that are implicated in tumor vasculature formation and maintenance, as well as tumor progression and…”
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7
Sir Ralph Howard Fowler, 1889-1944: a centenary lecture
Published in Notes and records of the Royal Society of London (01-01-1993)“…This paper records, more or less verbatim, a lecture to celebrate the centenary of the birth of Sir Ralph Fowler, given in October 1989 at Trinity College,…”
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Images in clinical medicine. Cholesterol emboli after coronary angioplasty
Published in The New England journal of medicine (23-03-2006)Get full text
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Design, Structure–Activity Relationship, and in Vivo Characterization of the Development Candidate NVP-HSP990
Published in Journal of medicinal chemistry (13-11-2014)“…Utilizing structure-based drug design, a novel dihydropyridopyrimidinone series which exhibited potent Hsp90 inhibition, good pharmacokinetics upon oral…”
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Evaluating Stent Optimisation Technique (StentBoost®) in a Dedicated Bifurcation Stent (the Tryton™)
Published in Cardiovascular revascularization medicine (01-03-2014)“…Abstract Background/Purpose To evaluate the use of StentBoost® in the Tryton™ dedicated SideBranch Stent. Methods & Results The Tryton™ SideBranch Stent has…”
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11
Nucleosynthesis Contributions to the Solar Nebula [and Discussion]
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical and physical sciences (30-09-1987)“…The discovery of isotopic anomalies in meteorites suggests that the Solar System is made of material from compositionally different and imperfectly mixed…”
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Getting the Wet out: Clean-up and Stabilization after a Fire
Published in APT bulletin (1986) (01-01-1992)Get full text
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Implementation of a modified version of NICE CG95 on chest pain of recent onset: experience in a DGH
Published in The British journal of cardiology (01-10-2016)Get full text
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Introduction to Panel Discussion: Chemistry and Cosmos
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical and physical sciences (29-07-1988)“…These remarks are intended to recall the general character of the models referred to in the title of the panel discussion, and to call attention to some of the…”
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Cholesterol Emboli after Coronary Angioplasty
Published in The New England journal of medicine (23-03-2006)“…A 72-year-old man presented with unstable angina. An urgent cardiac catheterization showed clinically significant disease in the right coronary artery, which…”
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16
Some Thoughts on Sun-Weather Relations [and Discussion]
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical and physical sciences (24-04-1990)“…Recent measurements of variations in the total solar irradiance now offer a quantitative mechanism through which year-to-year changes in solar activity may…”
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Stable Isotope Measurements of Meteorites and Cosmic Dust Grains [and Discussion]
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical and physical sciences (30-09-1987)“…Although it was well known that a high13C abundance was a common feature of the spectra of evolved stars, it took over 50 years to find evidence of…”
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Spontaneous coronary artery dissection as a cause of sudden cardiac death in the peripartum period
Published in BMJ case reports (01-12-2010)“…Spontaneous coronary artery dissection is a rare cause of acute coronary syndromes and can be potentially fatal. The authors describe a case of multi-vessel…”
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Capecitabine induced acute coronary syndrome
Published in BMJ case reports (2009)“…Capecitabine is an oral chemotherapeutic agent recommended by the National Institute for Clinical Excellence as first line treatment for metastatic bowel…”
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LHMDS mediated tandem acylation–cyclization of 2-aminobenzenecarbonitriles with 2-benzymidazol-2-yl acetates: a short and efficient route to the synthesis of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones
Published in Tetrahedron letters (30-01-2006)“…We herein describe the discovery of a mild, one-pot, tandem acylation–cyclization for the synthesis of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones from…”
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