Search Results - "McCraith, Stephen"

Nivolumab plus relatlimab in patients with previously treated microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer: the phase II CheckMate 142 study by Overman, Michael J, Gelsomino, Fabio, Aglietta, Massimo, Wong, Mark, Limon Miron, Maria Luisa, Leonard, Gregory, García-Alfonso, Pilar, Hill, Andrew G, Cubillo Gracian, Antonio, Van Cutsem, Eric, El-Rayes, Bassel, McCraith, Stephen M, He, Beilei, Lei, Ming, Lonardi, Sara

“…BackgroundProgrammed death-1 (PD-1) inhibitors, including nivolumab, have demonstrated long-term survival benefit in previously treated patients with…”
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Genome-Wide Analysis of Vaccinia Virus Protein-Protein Interactions by McCraith, Stephen, Holtzman, Ted, Moss, Bernard, Fields, Stanley

“…To detect interactions between proteins of vaccinia virus, we carried out a comprehensive two-hybrid analysis to assay every pairwise combination. We…”
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The Spatial Organization of Lipid Synthesis in the Yeast Saccharomyces cerevisiae Derived from Large Scale Green Fluorescent Protein Tagging and High Resolution Microscopy by Natter, Klaus, Leitner, Peter, Faschinger, Alexander, Wolinski, Heimo, McCraith, Stephen, Fields, Stanley, Kohlwein, Sepp D

“…The localization pattern of proteins involved in lipid metabolism in the yeast Saccharomyces cerevisiae was determined using C-terminal green fluorescent…”
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A Biochemical Genomics Approach for Identifying Genes by the Activity of Their Products by Martzen, Mark R., McCraith, Stephen M., Spinelli, Sherry L., Torres, Francy M., Fields, Stanley, Grayhack, Elizabeth J., Phizicky, Eric M.

“…For the identification of yeast genes specifying biochemical activities, a genomic strategy that is rapid, sensitive, and widely applicable was developed with…”
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Biochemical genomics approach to map activities to genes by Phizicky, Eric M, Martzen, Mark R, McCraith, Stephen M, Spinelli, Sherry L, Xing, Feng, Shull, Neil P, Van Slyke, Ceri, Montagne, Rebecca K, Torres, Francy M, Fields, Stanley, Grayhack, Elizabeth J

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First-line (1L) nivolumab (NIVO) plus chemotherapy (chemo) vs chemo in patients (pts) with advanced gastric cancer, gastroesophageal junction cancer, and esophageal adenocarcinoma (GC/GEJC/EAC): CheckMate 649 Chinese subgroup analysis 4-year (yr) follow-up by Shen, Lin, Bai, Yuxian, Lin, Xiaoyan, Li, Wei, Wang, Jufeng, Zhang, Xiaochun, Pan, Hongming, Bai, Chunmei, Bai, Li, Cheng, Ying, Zhang, Jingdong, Zhong, Haijun, Ba, Yi, Hu, Wenwei, Xu, Rui-Hua, Guo, Weijian, Qin, Shukui, Wang, Rui, McCraith, Stephen, Liu, Tianshu

“…318 Background: NIVO + chemo demonstrated clinically meaningful improvement in overall survival (OS) and an acceptable safety profile vs chemo in previously…”
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An NAD Derivative Produced During Transfer RNA Splicing: ADP-Ribose 1″-2″ Cyclic Phosphate by Culver, Gloria M., McCraith, Stephen M., Zillmann, Martin, Kierzek, Ryszard, Michaud, Neil, LaReau, Richard D., Turner, Douglas H., Phizicky, Eric M.

“…Transfer RNA (tRNA) splicing is essential in Saccharomyces cerevisiae as well as in humans, and many of its features are the same in both. In yeast, the final…”
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First-line (1L) nivolumab (NIVO) + ipilimumab (IPI) in patients (pts) with microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC): 64-month (mo) follow-up from CheckMate 142 by Lenz, Heinz-Josef, Overman, Michael J., Van Cutsem, Eric, Limon, Maria Luisa, Wong, Ka Yeung Mark, Hendlisz, Alain, Aglietta, Massimo, Garcia-Alfonso, Pilar, Neyns, Bart, Gelsomino, Fabio, Cardin, Dana Backlund, Dragovich, Tomislav, Shah, Usman, McCraith, Stephen, Wang, Rui, Lei, Ming, Yao, Jin, Jin, Lixian, Lonardi, Sara

“…97 Background: NIVO + IPI demonstrated robust, durable clinical benefit and was well tolerated as a 1L therapy in pts with MSI-H/dMMR mCRC in the phase 2…”
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First-line (1L) nivolumab (NIVO) + ipilimumab (IPI) in patients (pts) with microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC): 64-month (mo) follow-up from CheckMate 142 by Lenz, Heinz-Josef, Overman, Michael J., Van Cutsem, Eric, Limon, M. Luisa, Wong, Mark Ka, Hendlisz, Alain, Aglietta, Massimo, Garcia-Alfonso, Pilar, Neyns, Bart, Gelsomino, Fabio, Cardin, Dana Backlund, Dragovich, Tomislav, Shah, Usman, McCraith, Stephen M., Wang, Abigail, Lei, Ming, Yao, Jin, Jin, Lixian, Lonardi, Sara

“…3550 Background: NIVO + IPI demonstrated robust, durable clinical benefit, and was well tolerated as a 1L therapy in pts with MSI-H/dMMR mCRC in the phase 2…”
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A 2′-Phosphotransferase Implicated in tRNA Splicing Is Essential in Saccharomyces cerevisiae by Culver, Gloria M., McCraith, Stephen M., Consaul, Sandra A., Stanford, David R., Phizicky, Eric M.

“…The last step of tRNA splicing in the yeastSaccharomyces cerevisiae is catalyzed by an NAD-dependent 2′-phosphotransferase, which transfers the splice junction…”
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An enzyme from Saccharomyces cerevisiae uses NAD+ to transfer the splice junction 2'-phosphate from ligated tRNA to an acceptor molecule by McCraith, S.M. (University of Rochester, Rochester, NY), Phizicky, E.M

“…An enzyme from Saccharomyces cerevisiae which removes the splice junction 2'-phosphate from ligated tRNA appears to require NAD+. This two-component enzyme has…”
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A highly specific phosphatase from Saccharomyces cerevisiae implicated in tRNA splicing by MCCRAITH, S. M, PHIZICKY, E. M

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification, characterization, and purification of an NAD(+)-dependent 2'-phosphotransferase from Saccharomyces cerevisiae implicated in transfer RNA splicing by McCraith, Stephen M

“…Two of the activities involved in the splicing of precursor tRNAs in Saccharomyces cerevisiae have been identified: an endonuclease which catalyzes the removal…”
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A Highly Specific Phosphatase from Saccharomyces cerevisiae Implicated in tRNA Splicing by Mccraith, Stephen M., Phizicky, Eric M.

“…We identified and partially purified a phosphatase from crude extracts of Saccharomyces cerevisiae cells that can catalyze the last step of tRNA splicing in…”
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A 2′-Phosphotransferase Implicated in tRNA Splicing Is Essential in Saccharomyces cerevisiae by Gloria M. Culver, Stephen M. McCraith, Sandra A. Consaul, David R. Stanford, Eric M. Phizicky

“…The last step of tRNA splicing in the yeast Saccharomyces cerevisiae is catalyzed by an NAD-dependent 2′-phosphotransferase, which transfers the splice…”
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