Search Results - "McCrady, C W"

γ-interferon plays a key role in T-cell-induced tumor regression by TUTTLE, T. M, MCCRADY, C. W, INGE, T. H, MOZHDEH SALOUR, BEAR, H. D

“…Recent studies have demonstrated that noncytolytic T-cells can mediate regression of murine tumors. In this report, we demonstrate that MCA-105 tumor-draining…”
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Coordination and reversibility of signals for proliferative activation and interleukin-2 mRNA production in resting human T lymphocytes by phorbol ester and calcium ionophore by McCrady, C W, Ely, C M, Westin, E, Carchman, R A

“…Sequential stimulation and washout procedures were employed to examine the kinetics and reversibility of pharmacologically manipulated second messenger signals…”
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Modulation of the activity of a human granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein (pIXY 321) by the macrocyclic lactone protein kinase C activator bryostatin 1 by McCrady, C W, Li, F, Pettit, G R, Grant, S

“…We have examined the effect of the macrocyclic lactone protein kinase C (PK-C) activator bryostatin 1 on the proliferative capacity and lineage commitment of…”
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Bryostatin 1 modulates the proliferation and lineage commitment of human myeloid progenitor cells exposed to recombinant interleukin-3 and recombinant granulocyte-macrophage colony-stimulating factor by LI, F, GRANT, S, PETTIT, G. R, MCCRADY, C. W

“…The activity of protein kinase C (PK-C) has been implicated in the regulation of the growth and differentiation of both normal and neoplastic hematopoietic…”
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Induction of tumoricidal activity and alterations of growth by interleukin-2 and manipulation of protein kinase C and cytosolic calcium in childhood acute lymphocytic leukemia cells by Massey, G V, McCrady, C W, Dunn, N L, Russell, E C, Carchman, R A

“…Signals from many receptor-ligand interactions are mediated by enhancement of phospholipid hydrolysis which generates metabolic intermediates stimulating…”
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Expansion and tumour specific cytokine secretion of bryostatin-activated T-cells from cryopreserved axillary lymph nodes of breast cancer patients by Lind, D S, Tuttle, T M, Bethke, K P, Frank, J L, McCrady, C W, Bear, H D

“…Current adoptive immunotherapy strategies in cancer patients require large numbers of activated T-cells and are limited by the availability of autologous…”
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Bryostatin 1-activated T cells can traffic and mediate tumor regression by Tuttle, T M, Bethke, K P, Inge, T H, McCrady, C W, Pettit, G R, Bear, H D

“…Adoptive immunotherapy in humans may be limited by the lack of autologous tumor cells to activate and expand tumor-specific T cells. Pharmacologic manipulation…”
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Corticosteroids inhibit the delivery of short-term activational pulses of phorbol ester and calcium ionophore to human peripheral T cells by McVicar, D W, McCrady, C W, Merchant, R E

“…Although there is evidence that corticosteroids inhibit receptor-ligand-induced phospholipid hydrolysis, the immunosuppressive effects of these agents…”
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Angiofollicular lymph node hyperplasia (Castleman's disease) in an adolescent female. Clinical and immunologic findings by Massey, G V, Kornstein, M J, Wahl, D, Huang, X L, McCrady, C W, Carchman, R A

“…Angiofollicular lymph node hyperplasia is a heterogeneous disorder of unclear etiology and has a wide spectrum of systemic symptoms. This report describes a…”
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Activation and growth of murine tumor-specific T-cells which have In vivo activity with bryostatin 1 by TUTTLE, T. M, INGE, T. H, BETHKE, K. P, MCCRADY, C. W, PETTIT, G. R, BEAR, H. D

“…We examined the ability of bryostatin 1 (Bryo), a novel protein kinase C activator, plus ionomycin (Io), a calcium ionophore, to activate T-cells with specific…”
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A comparison of serum-free media for the support of in vitro mitogen-induced blastogenic expansion of cytolytic lymphocytes by MCVICAR, D. W, FEI LI, MCCRADY, C. W, MERCHANT, R. E

“…The high cost and potential dangers of including human AB serum in incubation media used to expand lymphocyte populations in vitro for adoptive immunotherapy…”
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Alteration of human lymphokine-activated killer cell activity by manipulation of protein kinase C and cytosolic Ca2 by MCCRADY, C. W, FEI LI, GRANT, A. J, MERCHANT, R. E, CARCHMAN, R. A

“…We have examined the effects of protein kinase C (PK-C) stimulation and cytosolic Ca2+ elevation on the in vitro induction of non-histocompatibility-restricted…”
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Effect of pharmacologic manipulation of protein kinase C by phorbol dibutyrate and bryostatin 1 on the clonogenic response of human granulocyte-macrophage progenitors to recombinant GM-CSF by McCrady, C W, Staniswalis, J, Pettit, G R, Howe, C, Grant, S

“…The effect of pharmacologic manipulation of protein kinase C (PK-C) activity on the response of committed human myeloid progenitor cells (CFU-GM) to…”
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Alteration of human lymphokine-activated killer cell activity by manipulation of protein kinase C and cytosolic Ca super(2+) by McCrady, C W, Li, F, Grant, A J, Merchant, R E, Carchman, R A

“…The authors have examined the effects of protein kinase C (PK-C) stimulation and cytosolic Ca super(2+) elevation on the in vitro induction of…”
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Bryostatin 1 modulates the proliferation and lineage commitment of human myeloid progenitor cells exposed to recombinant interleukin-3 and recombinant granulocyte-macrophage colony-stimulating factor by Li, F, Grant, S, Pettit, GR, McCrady, CW

“…The activity of protein kinase C (PK-C) has been implicated in the regulation of the growth and differentiation of both normal and neoplastic hematopoietic…”
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