Search Results - "McCracken, Lindsay M."

Zinc-Dependent Modulation of α2- and α3-Glycine Receptor Subunits by Ethanol by McCracken, Lindsay M., Trudell, James R., McCracken, Mandy L., Harris, R. Adron

“…Background Strychnine‐sensitive glycine receptors (GlyRs) are expressed throughout the brain and spinal cord and are among the strongly supported protein…”
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Mutation of a zinc-binding residue in the glycine receptor α1 subunit changes ethanol sensitivity in vitro and alcohol consumption in vivo by McCracken, Lindsay M, Blednov, Yuri A, Trudell, James R, Benavidez, Jillian M, Betz, Heinrich, Harris, R Adron

“…Ethanol is a widely used drug, yet an understanding of its sites and mechanisms of action remains incomplete. Among the protein targets of ethanol are glycine…”
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Effects of Acamprosate on Neuronal Receptors and Ion Channels Expressed in Xenopus Oocytes by Reilly, Matthew T., Lobo, Ingrid A., McCracken, Lindsay M., Borghese, Cecilia M., Gong, Diane, Horishita, Takafumi, Adron Harris, R.

“…Background:  Acamprosate (calcium acetylhomotaurinate) has proven to be a moderately effective pharmacological adjunct for the treatment of alcoholism…”
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Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain by McCracken, Lindsay M., Lowes, Daniel C., Salling, Michael C., Carreau-Vollmer, Cyndel, Odean, Naomi N., Blednov, Yuri A., Betz, Heinrich, Harris, R. Adron, Harrison, Neil L.

“…Neuronal inhibition can occur via synaptic mechanisms or through tonic activation of extrasynaptic receptors. In spinal cord, glycine mediates synaptic…”
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Inter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor by McCracken, Mandy L, Gorini, Giorgio, McCracken, Lindsay M, Mayfield, R Dayne, Harris, R Adron, Trudell, James R

“…Glycine receptors (GlyRs) mediate inhibitory neurotransmission and are targets for alcohols and anesthetics in brain. GlyR transmembrane (TM) domains contain…”
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Zinc enhances ethanol modulation of the α1 glycine receptor by McCracken, Lindsay M., Trudell, James R., Goldstein, Beth E., Harris, R. Adron, Mihic, S. John

“…Glycine receptor function mediates most inhibitory neurotransmission in the brainstem and spinal cord and is enhanced by alcohols, volatile anesthetics,…”
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Zinc-Dependent Modulation of [alpha]2- and [alpha]3-Glycine Receptor Subunits by Ethanol by McCracken, Lindsay M, Trudell, James R, McCracken, Mandy L, Harris, R Adron

“…Background Strychnine-sensitive glycine receptors (GlyRs) are expressed throughout the brain and spinal cord and are among the strongly supported protein…”
Get full text

Zinc enhances ethanol modulation of the a1 glycine receptor by McCracken, Lindsay M, Trudell, James R, Goldstein, Beth E, Harris, RAdron, Mihic, SJohn

“…Glycine receptor function mediates most inhibitory neurotransmission in the brainstem and spinal cord and is enhanced by alcohols, volatile anesthetics,…”
Get full text

Zinc enhances ethanol modulation of the alpha1 glycine receptor by McCracken, Lindsay M, Trudell, James R, Goldstein, Beth E, Harris, R Adron, Mihic, S John

“…Glycine receptor function mediates most inhibitory neurotransmission in the brainstem and spinal cord and is enhanced by alcohols, volatile anesthetics,…”
Get full text