Search Results - "McCoull, D."

Aprepitant is a novel, selective activator of the K2P channel TRAAK by McCoull, D., Veale, E.L., Walsh, Y., Byrom, L., Avkiran, T., Large, J.M., Vaitone, E., Gaffey, F., Jerman, J., Mathie, A., Wright, P.D.

“…TRAAK (KCNK4, K2P4.1) is a mechanosensitive two-pore domain potassium (K2P) channel. Due to its expression within sensory neurons and genetic link to…”
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Dihydrodiol Dehydrogenases and Polycyclic Aromatic Hydrocarbon Activation:  Generation of Reactive and Redox Active o-Quinones by Penning, Trevor M, Burczynski, Michael E, Hung, Chien-Fu, McCoull, Kirsten D, Palackal, Nisha T, Tsuruda, Laurie S

“…Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants and may be causative agents in human lung cancer. They are considered…”
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Synthesis and Characterization of Polycyclic Aromatic Hydrocarbon o-Quinone Depurinating N7-Guanine Adducts by McCoull, Kirsten D, Rindgen, Diane, Blair, Ian A, Penning, Trevor M

“…Polycyclic aromatic hydrocarbons (PAHs) are environmental pollutants which may cause cancer and require metabolic activation to exert their carcinogenic…”
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