Search Results - "McCosh, Richard B"

Patterns of population epigenomic diversity by Schmitz, Robert J., Schultz, Matthew D., Urich, Mark A., Nery, Joseph R., Pelizzola, Mattia, Libiger, Ondrej, Alix, Andrew, McCosh, Richard B., Chen, Huaming, Schork, Nicholas J., Ecker, Joseph R.

“…Natural epigenetic variation provides a source for the generation of phenotypic diversity, but to understand its contribution to such diversity, its…”
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Estradiol Enables Chronic Corticosterone to Inhibit Pulsatile Luteinizing Hormone Secretion and Suppress Kiss1 Neuronal Activation in Female Mice by Kreisman, Michael J, McCosh, Richard B, Tian, Katherine, Song, Christopher I, Breen, Kellie M

“…Two common responses to stress include elevated circulating glucocorticoids and impaired luteinizing hormone (LH) secretion. We have previously shown that a…”
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Insulin‐induced hypoglycaemia suppresses pulsatile luteinising hormone secretion and arcuate Kiss1 cell activation in female mice by McCosh, Richard B., Kreisman, Michael J., Tian, Katherine, Ho, Bryan S., Thackray, Varykina G., Breen, Kellie M.

“…Stress suppresses pulsatile luteinising hormone (LH) secretion in a variety of species, although the mechanism underlying this inhibition of reproductive…”
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Neural and endocrine mechanisms underlying stress-induced suppression of pulsatile LH secretion by McCosh, Richard B., Breen, Kellie M., Kauffman, Alexander S.

“…Stress is well-known to inhibit a variety of reproductive processes, including the suppression of episodic Gonadotropin releasing hormone (GnRH) secretion,…”
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A Modified Ultra-Sensitive ELISA for Measurement of LH in Mice by Kreisman, Michael J, McCosh, Richard B, Breen, Kellie M

“…A major obstacle to monitoring pulsatile luteinizing hormone (LH) secretion in mice has been an assay with sufficient sensitivity in small blood volumes. In…”
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Neuroendocrine Basis for Disrupted Ovarian Cyclicity in Female Mice During Chronic Undernutrition by Kreisman, Michael J, Tadrousse, Kirollos S, McCosh, Richard B, Breen, Kellie M

“…Abstract Chronic undernutrition is a type of metabolic stress that impairs reproduction in multiple species. Although energy balance and female reproductive…”
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Regulation of the gonadotropin‐releasing hormone neuron during stress by McCosh, Richard B., O'Bryne, Kevin T., Karsch, Fred J., Breen, Kellie M.

“…The effect of stress on reproduction and gonadal function has captivated investigators for almost 100 years. Following the identification of…”
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Norepinephrine Neurons in the Nucleus of the Solitary Tract Suppress Luteinizing Hormone Secretion in Female Mice by McCosh, Richard B, Kreisman, Michael J, Tian, Katherine, Thomas, Steven A, Breen Church, Kellie M

“…Stress impairs fertility, at least in part, via inhibition of gonadotropin secretion. Luteinizing hormone (LH) is an important gonadotropin that is released in…”
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Peripheral interleukin-1β inhibits arcuate kiss1 cells and LH pulses in female mice by Makowski, Katherine N, Kreisman, Michael J, McCosh, Richard B, Raad, Ali A, Breen, Kellie M

“…Peripheral immune/inflammatory challenges rapidly disrupt reproductive neuroendocrine function. This inhibition is considered to be centrally mediated via…”
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Frequent Tail-tip Blood Sampling in Mice for the Assessment of Pulsatile Luteinizing Hormone Secretion by McCosh, Richard B, Kreisman, Michael J, Breen, Kellie M

“…In many endocrine systems, circulating factors or hormones are not released continuously, but are secreted as a discrete pulse in response to a releasing…”
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Do Substance P and Neurokinin A Play Important Roles in the Control of LH Secretion in Ewes? by Fergani, Chrysanthi, Mazzella, Leanne, Coolen, Lique M, McCosh, Richard B, Hardy, Steven L, Newcomb, Nora, Grachev, Pasha, Lehman, Michael N, Goodman, Robert L

“…There is now general agreement that neurokinin B (NKB) acts via neurokinin-3-receptor (NK3R) to stimulate secretion of GnRH and LH in several species,…”
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Localization of kisspeptin, NKB, and NK3R in the hypothalamus of gilts treated with the progestin altrenogest by Lindo, Ashley N, Thorson, Jennifer F, Bedenbaugh, Michelle N, McCosh, Richard B, Lopez, Justin A, Young, Samantha A, Meadows, Lanny J, Bowdridge, Elizabeth C, Fergani, Chrysanthi, Freking, Bradley A, Lehman, Michael N, Hileman, Stanley M, Lents, Clay A

“…Mechanisms in the brain controlling secretion of gonadotropin hormones in pigs, particularly luteinizing hormone (LH), are poorly understood. Kisspeptin is a…”
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Evidence that Nitric Oxide Is Critical for LH Surge Generation in Female Sheep by McCosh, Richard B, Lopez, Justin A, Szeligo, Brett M, Bedenbaugh, Michelle N, Hileman, Stanley M, Coolen, Lique M, Lehman, Michael N, Goodman, Robert L

“…Abstract Elevated and sustained estradiol concentrations cause a gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) surge that is necessary for…”
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Evidence That the LH Surge in Ewes Involves Both Neurokinin B-Dependent and -Independent Actions of Kisspeptin by Goodman, Robert L, He, Wen, Lopez, Justin A, Bedenbaugh, Michelle N, McCosh, Richard B, Bowdridge, Elizabeth C, Coolen, Lique M, Lehman, Michael N, Hileman, Stanley M

“…Recent evidence has implicated neurokinin B (NKB) signaling in the retrochiasmatic area (RCh) of the ewe in the LH surge. To test this hypothesis, we first…”
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Evidence That Endogenous Somatostatin Inhibits Episodic, but Not Surge, Secretion of LH in Female Sheep by McCosh, Richard B., Szeligo, Brett M., Bedenbaugh, Michelle N., Lopez, Justin A., Hardy, Steven L., Hileman, Stanley M., Lehman, Michael N., Goodman, Robert L.

“…Abstract Two modes of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) secretion are necessary for female fertility: surge and episodic…”
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Morphological and functional evidence for sexual dimorphism in neurokinin B signalling in the retrochiasmatic area of sheep by Lopez, Justin A., Bowdridge, Elizabeth C., McCosh, Richard B., Bedenbaugh, Michelle N., Lindo, Ashley N., Metzger, Makayla, Haller, Megan, Lehman, Michael N., Hileman, Stanley M., Goodman, Robert L.

“…Neurokinin B (NKB) is critical for fertility in humans and stimulates gonadotrophin‐releasing hormone/luteinising hormone (LH) secretion in several species,…”
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Relationship of neuropeptide FF receptors with pubertal maturation of gilts by Thorson, Jennifer F, Heidorn, Neely L, Ryu, Vitaly, Czaja, Krzysztof, Nonneman, Danny J, Barb, C. Richard, Hausman, Gary J, Rohrer, Gary A, Prezotto, Ligia D, McCosh, Richard B, Wright, Elane C, White, Brett R, Freking, Bradley A, Oliver, William T, Hileman, Stanley M, Lents, Clay A

“…Mechanisms governing the timing of puberty in pigs are poorly understood. A genome-wide association study for age at first estrus in pigs identified candidate…”
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Regulation of the GnRH neuron during stress by McCosh, Richard B., O’Bryne, Kevin T., Karsch, Fred J., Breen, Kellie M.

“…The effect of stress on reproduction and gonadal function has captivated investigators for nearly 100 years. Following the identification of GnRH 50 years ago,…”
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7940 Is Urocortin 2 A Mediator Of Stress-induced Suppression Of The Luteinizing Hormone Surge? by Bell, Helen F, Carrasco, Rodrigo A, Kreisman, Michael J, McCosh, Richard B, Breen Church, Kellie M

“…Abstract Disclosure: H.F. Bell: None. R.A. Carrasco: None. M.J. Kreisman: None. R.B. McCosh: None. K.M. Breen Church: None. Stress is thought to be a…”
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SAT596 Evidence That Corticotropin-releasing Hormone Receptor 2 Activation Mediates Stress-induced Hyperglycemia by McCosh, Richard B, Kreisman, Michael J, Jang, Jessica, Jung, Jacklyn, Breen Church, Kellie M

“…Abstract Disclosure: R.B. McCosh: None. M.J. Kreisman: None. J. Jang: None. J. Jung: None. K.M. Breen Church: None. Stress-induced hyperglycemia refers to the…”
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