Search Results - "McConville, Patrick"

Vascular Targeted Nanoparticles for Imaging and Treatment of Brain Tumors by RAMACHANDRA REDDY, G, BHOJANI, Mahaveer S, JOHNSON, Timothy D, PHILBERT, Martin A, KOPELMAN, Raoul, REHEMTULLA, Alnawaz, ROSS, Brian D, MCCONVILLE, Patrick, MOODY, Jonathan, MOFFAT, Bradford A, HALL, Daniel E, KIM, Gwangseong, KOO, Yong-Eun L, WOOLLISCROFT, Michael J, SUGAI, James V

“…Purpose: Development of new therapeutic drug delivery systems is an area of significant research interest. The ability to directly target a therapeutic agent…”
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Multifunctional nanoparticle platforms for in vivo MRI enhancement and photodynamic therapy of a rat brain cancer by Kopelman, Raoul, Lee Koo, Yong-Eun, Philbert, Martin, Moffat, Bradford A., Ramachandra Reddy, G., McConville, Patrick, Hall, Daniel E., Chenevert, Thomas L., Bhojani, Mahaveer Swaroop, Buck, Sarah M., Rehemtulla, Alnawaz, Ross, Brian D.

“…A paradigm for brain cancer detection, treatment, and monitoring is established. Multifunctional biomedical nanoparticles (30–60 nm) containing photosensitizer…”
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Magnetic Resonance Imaging Determination of Tumor Grade and Early Response to Temozolomide in a Genetically Engineered Mouse Model of Glioma by MCCONVILLE, Patrick, HAMBARDZUMYAN, Dolores, MOODY, Jonathan B, LEOPOLD, Wilbur R, KREGER, Alicia R, WOOLLISCROFT, Michael J, REHEMTULLA, Alnawaz, ROSS, Brian D, HOLLAND, Eric C

“…Purpose: The median survival for patients diagnosed with glioblastoma multiforme, the most common type of brain tumor, is less than 1 year. Animal glioma…”
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Abstract PO-097: Selective targeting and imaging of orthotopic glioblastoma after a single systemic dose of a novel hydoxyl dendrimer radionuclide by Sharma, Rishi, Sun, Minghao, Appiani, Santiago, Coelho, Richard, McConville, Patrick, Alters, Susan, Cleland, Jeffrey L.

“…Abstract Previous studies have demonstrated hydroxyl dendrimers (HDs) are selectively taken up by tumor associated macrophages (TAMs) after a single…”
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Abstract 381: Macrophage tracking using multi-modality 3D imaging in xenografts by Dimant, Hemi, McConville, Patrick, Orcutt, Kelly, Mikule, Kieth, Wilcoxen, Keith, Lister, Deanne, Ahrens, Eric T.

“…Abstract A common approach to immunotherapy is to promote the accumulation of specific bone marrow-derived myeloid cells into tumors for anti-tumor activity…”
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Metallofluorocarbon Nanoemulsion for Inflammatory Macrophage Detection via PET and MRI by Wang, Chao, Leach, Benjamin I, Lister, Deanne, Adams, Stephen R, Xu, Hongyan, Hoh, Carl, McConville, Patrick, Zhang, Jing, Messer, Karen, Ahrens, Eric T

“…Inflammation is associated with a range of serious human conditions, including autoimmune and cardiovascular diseases and cancer. The ability to image active…”
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Water and Polymer Mobility in Hydrogel Biomaterials Quantified by 1H NMR:  A Simple Model Describing Both T1 and T2 Relaxation by MCCONVILLE, Patrick, WHITTAKER, Michael K., POPE, James M.

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Cryo-Fluorescence Tomography as a Tool for Visualizing Whole-Body Inflammation Using Perfluorocarbon Nanoemulsion Tracers by Leach, Benjamin I., Lister, Deanne, Adams, Stephen R., Bykowski, Julie, Schwartz, Amy B., McConville, Patrick, Dimant, Hemi, Ahrens, Eric T.

“…Purpose We explore the use of intravenously delivered fluorescent perfluorocarbon (PFC) nanoemulsion tracers and multi-spectral cryo-fluorescence tomography…”
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Correction: Cryo-Fluorescence Tomography as a Tool for Visualizing Whole-Body Inflammation Using Perfluorocarbon Nanoemulsion Tracers by Leach, Benjamin I., Lister, Deanne, Adams, Stephen R., Bykowski, Julie, Schwartz, Amy B., McConville, Patrick, Dimant, Hemi, Ahrens, Eric T.

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Correction to: Cryo-Fluorescence Tomography as a Tool for Visualizing Whole-Body Inflammation Using Perfluorocarbon Nanoemulsion Tracers by Leach, Benjamin I., Lister, Deanne, Adams, Stephen R., Bykowski, Julie, Schwartz, Amy B., McConville, Patrick, Dimant, Hemi, Ahrens, Eric T.

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Abstract 1146: Tepotinib treatment inhibits tumor growth and affects tumor permeability in an intracranial PDX model of MET -amplified NSCLC brain metastasis by Clark, Anderson, Albers, Joachim, McConville, Patrick, Stopka, Sylwia A., Regan, Michael S., DiPiazza, Marina, Agar, Nathalie Y.R.

“…Abstract Background: Tepotinib is approved to treat patients with NSCLC harboring MET exon 14 skipping. We previously provided preclinical proof of concept for…”
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Abstract 2066: Comparison of ADC MRI, T2-weighted MRI and combined T2-weighted/T1-contrast-enhanced/ADC MRI quantification of cerebral edema in an intracranial glioma model by Lister, Deanne, Balagurunathan, Deepa, Baugher, Meridith, Flecha, Athena, Trachet, Erin, Wise, Scott, Leopold, W.R., McConville, Patrick

“…Abstract Introduction: Brain edema is a prominent feature of brain cancer and contributes to neurologic dysfunction and impaired quality of life. Efficacious…”
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A Novel Polyacrylamide Magnetic Nanoparticle Contrast Agent for Molecular Imaging using MRI by Moffat, Bradford A., Reddy, G. Ramachandra, McConville, Patrick, Hall, Daniel E., Chenevert, Thomas L., Kopelman, Raoul R., Philbert, Martin, Weissleder, Ralph, Rehemtulla, Alnawaz, Ross, Brian D.

“…A novel Polyacrylamide superparamagnetic iron oxide nanoparticle platform is described which has been synthetically prepared such that multiple crystals of…”
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Abstract 4945: Evaluating the feasibility and throughput of quintuple modality imaging in a prostate cancer bone metastasis model with PET, SPECT, CT, MRI, and bioluminescence imaging by Chunta, John L., Lister, Deanne, Bull, Chris, Balagurunathan, Deepa, Trachet, Erin, Chiodo, Chris, Wise, Scott, Leopold, Dick, McConville, Patrick

“…Abstract Background: Multimodality imaging presents a unique opportunity to image the efficacy of candidate compounds against various models of cancer. The…”
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Abstract B152: MR-based assessment and quantification of cerebral edema in an orthotopic mouse glioma model by Lister, Deanne R., Balagurunathan, Deepa, Baugher, Meridith, Trachet, Erin, McConville, Patrick, Wise, Scott, Leopold, W.R.

“…Abstract Introduction: Brain edema is a prominent feature of brain cancer and contributes to neurologic dysfunction and impaired quality of life. While…”
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Abstract B15: Increased clinical relevance of orthotopic glioma models through bioluminescence and MR imaging by Lister, Deanne, Meade, Mary Anne, Woolliscroft, Tracey, Balagurunathan, Deepa, Trachet, Erin, Leopold, Wilbur, McConville, Patrick

“…Abstract Glioblastoma multiforme (GBM) is the most common and most aggressive form of malignant primary brain tumors, affecting nearly 35,000 people in the…”
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Abstract 2681: Combined Dynamic 18F-FDG PET Imaging and DCE MRI prediction of treatment response in an orthotopic model of glioblastoma multiforme by Trachet, Erin, Chunta, John, Bull, Chris, Baranski, Jeni, Woolliscroft, Tracey, Lister, Deanne, McConville, Patrick, Leopold, Dick

“…Abstract BACKGROUND: Gliobastomas (GBM) are highly aggressive tumors. When patients are treated with the standard of care of combined radiation therapy and…”
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Abstract 3929: Orthotopic human choroidal melanoma model characterization with bioluminescence and magnetic resonance imaging for therapeutic efficacy evaluation by Chunta, John L., Baugher, Meridith, Lister, Deanne, Trachet, Erin, Guley, Kevin P., Bull, Chris, Wise, Scott, Leopold, Wilbur R., McConville, Patrick

“…Abstract BACKGROUND: Intraocular melanomas in the West represents 70% of all primary eye cancers with a mortality rate greater than 50%. Current treatment…”
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Small animal preparation and handling in MRI by McConville, Patrick

“…Animal handling and preparation is one of the most critical aspects of in vivo NMR imaging in small animals, and involves a broad spectrum of challenges, any…”
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Abstract B142: Evaluating the feasibility and throughput of quintuple modality imaging in disseminated models of cancer with PET, CT, MRI, bioluminescence, and fluorescence molecular tomography by Chunta, John L., Lister, Deanne, Bull, Chris, Balagurunathan, Deepa, Trachet, Erin, Chiodo, Chris, Wise, Scott, Leopold, Wilbur R., McConville, Patrick

“…Abstract Background: Multimodality imaging presents a unique opportunity to image the efficacy of candidate compounds against various models of cancer. The…”
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