Search Results - "McConnell, Ona L."

A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels by Reddy, Kaalak, Jenquin, Jana R., McConnell, Ona L., Cleary, John D., Richardson, Jared I., Pinto, Belinda S., Haerle, Maja C., Delgado, Elizabeth, Planco, Lori, Nakamori, Masayuki, Wang, Eric T., Berglund, J. Andrew

“…A CTG repeat expansion in the DMPK gene is the causative mutation of myotonic dystrophy type 1 (DM1). Transcription of the expanded CTG repeat produces toxic…”
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Automated intracellular pharmacological electrophysiology for ligand-gated ionotropic receptor and pharmacology screening by Perszyk, Riley E, Yip, Mighten C, McConnell, Ona L, Wang, Eric T, Jenkins, Andrew, Traynelis, Stephen F, Forest, Craig R

“…Communication between neuronal cells, central to brain function, is performed by several classes of ligand-gated ionotropic receptors. The gold standard…”
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An engineered RNA binding protein with improved splicing regulation by Hale, Melissa A, Richardson, Jared I, Day, Ryan C, McConnell, Ona L, Arboleda, Juan, Wang, Eric T, Berglund, J Andrew

“…Abstract The muscleblind-like (MBNL) family of proteins are key developmental regulators of alternative splicing. Sequestration of MBNL proteins by expanded…”
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Conservation of context-dependent splicing activity in distant Muscleblind homologs by Oddo, Julia C, Saxena, Tanvi, McConnell, Ona L, Berglund, J Andrew, Wang, Eric T

“…The Muscleblind (MBL) protein family is a deeply conserved family of RNA binding proteins that regulate alternative splicing, alternative polyadenylation, RNA…”
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