Search Results - "McConnell, D J"

Tissue distribution and ontogeny of steroid 5α-reductase isozyme expression by THIGPEN, A. E, SILVER, R. I, GUILEYARDO, J. M, CASEY, M. L, MCCONNELL, J. D, RUSSELL, D. W

“…The synthesis of dihydrotestosterone is catalyzed by steroid 5 alpha-reductase isozymes, designated types 1 and 2. Mutation of type 2 results in male…”
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The Effect of Finasteride on the Risk of Acute Urinary Retention and the Need for Surgical Treatment among Men with Benign Prostatic Hyperplasia by McConnell, John D, Bruskewitz, Reginald, Walsh, Patrick, Andriole, Gerald, Lieber, Michael, Holtgrewe, H. Logan, Albertsen, Peter, Roehrborn, Claus G, Nickel, J. Curtis, Wang, Daniel Z, Taylor, Alice M, Waldstreicher, Joanne

“…Benign prostatic hyperplasia is common among older men, and its symptoms interfere with normal activities and reduce the sense of well-being. 1 It can also be…”
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Relationship of symptoms of prostatism to commonly used physiological and anatomical measures of the severity of benign prostatic hyperplasia by Barry, M J, Cockett, A T, Holtgrewe, H L, McConnell, J D, Sihelnik, S A, Winfield, H N

“…In previous studies the severity of symptoms of prostatism in men with benign prostatic hyperplasia have not correlated well with prostate size, degree of…”
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Finasteride, an inhibitor of 5 alpha-reductase, suppresses prostatic dihydrotestosterone in men with benign prostatic hyperplasia by McConnell, J D, Wilson, J D, George, F W, Geller, J, Pappas, F, Stoner, E

“…The oral administration of finasteride, a 4-aza-steroid inhibitor of 5 alpha-reductase, decreases serum dihydrotestosterone levels, but has little effect on…”
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The Effect of Finasteride in Men with Benign Prostatic Hyperplasia by Gormley, Glenn J, Stoner, Elizabeth, Bruskewitz, Reginald C, Imperato-McGinley, Julianne, Walsh, Patrick C, McConnell, John D, Andriole, Gerald L, Geller, Jack, Bracken, Bruce R, Tenover, Joyce S, Vaughan, E. Darracott, Pappas, Frances, Taylor, Alice, Binkowitz, Bruce, Ng, Jennifer

“…BENIGN prostatic hyperplasia is common in aging men. The resulting enlargement of the prostate gland can lead to urethral obstruction and even complete urinary…”
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Analysis of factors contributing to success or failure of 1-stage urethroplasty for urethral stricture disease by Roehrborn, C G, McConnell, J D

“…We reviewed charts with adequate documentation and followup (mean 24.6 months) between 1970 and 1987 of 110 patients who had undergone 1-stage urethroplasty…”
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The development of urology in the 21st century by McConnell, J.D.

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Cell type specific expression of steroid 5 alpha-reductase 2 by Silver, R I, Wiley, E L, Thigpen, A E, Guileyardo, J M, McConnell, J D, Russell, D W

“…Isozymes of steroid 5 alpha-reductase (5 alpha-reductase) have crucial roles in androgen physiology by synthesizing the potent hormone dihydrotestosterone. The…”
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Genetic control of bacterial suicide: regulation of the induction of PBSX in Bacillus subtilis by MCDONNELL, G. E, WOOD, H, DEVINE, K. M, MCCONNELL, D. J

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Expression and regulation of steroid 5 alpha-reductase 2 in prostate disease by Silver, R I, Wiley, E L, Davis, D L, Thigpen, A E, Russell, D W, McConnell, J D

“…The androgen dihydrotestosterone is synthesized by the enzyme steroid 5 alpha-reductase, and it is required for growth and development of the prostate. We used…”
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Expression of the human mismatch repair gene hMSH2 : A potential marker for urothelial malignancy by LEACH, F. S, HSIEH, J.-T, MOLBERG, K, HOSSEIN SABOORIAN, M, MCCONNELL, J. D, SAGALOWSKY, A. I

“…The human mismatch repair (MMR) gene hMSH2 (human mutS homolog-2) is a DNA repair gene that has been reported to be mutated in 40% of hereditary nonpolyposis…”
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Physiologic sequelae of partial infravesical obstruction in the mouse: role of inducible nitric oxide synthase by Lemack, G E, Burkhard, F, Zimmern, P E, McConnell, J D, Lin, V K

“…To develop a mouse model for partial infravesical obstruction, and determine the resultant changes in bladder function, with particular emphasis on the role of…”
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Overproduction, isolation, and DNA-binding characteristics of Xre, the repressor protein from the Bacillus subtilis defective prophage PBSX by MCDONNELL, G. E, MCCONNELL, D. J

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Contractile protein expression in bladder smooth muscle is a marker of phenotypic modulation after outlet obstruction in the rabbit model by Burkhard, F C, Lemack, G E, Zimmern, P E, Lin, V K, McConnell, J D

“…We determined changes in contractile protein expression before and after the relief of partial bladder outlet obstruction in the rabbit model and assessed…”
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Activation of a Bacterial Lipase by its Chaperone by Hobson, Audrey H., Buckley, Catherine M., Aamand, Jesper L., Jorgensen, Steen T., Diderichsen, Borge, McConnell, David J.

“…The gene lipA of Pseudomonas cepacia DSM 3959 encodes a prelipase from which a signal peptide is cleaved during secretion, producing a mature extracellular…”
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Androgen ablation and blockade in the treatment of benign prostatic hyperplasia by McConnell, J D

“…Antiandrogen therapy appears to produce a 30 to 40 per cent decrease in the volume of the hyperplastic prostate after 3 to 6 months of therapy (Table 5)…”
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Prostatic growth: new insights into hormonal regulation by McConnell, J D

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Increased expression of early growth response-1 messenger ribonucleic acid in prostatic adenocarcinoma by Thigpen, A E, Cala, K M, Guileyardo, J M, Molberg, K H, McConnell, J D, Russell, D W

“…We isolated genes whose expression differs between normal and malignant prostate. Differential display polymerase chain reactions revealed a messenger…”
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Characterization of PBSX, a defective prophage of Bacillus subtilis by WOOD, H. E, DAWSON, M. T, DEVINE, K. M, MCCONNELL, D. J

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Replication and segregational stability of Bacillus plasmid pBAA1 by DEVINE, K. M, HOGAN, S. T, HIGGINS, D. G, MCCONNELL, D. J

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