Search Results - "McConkey, Brendan J"

The GRHL2/ZEB Feedback Loop—A Key Axis in the Regulation of EMT in Breast Cancer by Mooney, Steven M., Talebian, Vida, Jolly, Mohit Kumar, Jia, Dongya, Gromala, Monica, Levine, Herbert, McConkey, Brendan J.

“…ABSTRACT More than 90% of cancer‐related deaths are caused by metastasis. Epithelial‐to‐Mesenchymal Transition (EMT) causes tumor cell dissemination while the…”
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Pathogen-secreted proteases activate a novel plant immune pathway by Cheng, Zhenyu, Li, Jian-Feng, Niu, Yajie, Zhang, Xue-Cheng, Woody, Owen Z., Xiong, Yan, Djonović, Slavica, Millet, Yves, Bush, Jenifer, McConkey, Brendan J., Sheen, Jen, Ausubel, Frederick M.

“…In Arabidopsis thaliana , pathogen-secreted proteases trigger a previously unknown defence response involving heterotrimeric G-protein complexes upstream of a…”
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New insights into 1-aminocyclopropane-1-carboxylate (ACC) deaminase phylogeny, evolution and ecological significance by Nascimento, Francisco X, Rossi, Márcio J, Soares, Cláudio R F S, McConkey, Brendan J, Glick, Bernard R

“…The main objective of this work is the study of the phylogeny, evolution and ecological importance of the enzyme 1-aminocyclopropane-1-carboxylate (ACC)…”
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Combined effects of the plant growth-promoting bacterium Pseudomonas putida UW4 and salinity stress on the Brassica napus proteome by Cheng, Zhenyu, Woody, Owen Z., McConkey, Brendan J., Glick, Bernard R.

“…► Bacterial ACC deaminase alleviates salinity stress on plants. ► Proteomic investigations revealed the individual and combined effects of bacterium and…”
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Modular Evolution and the Origins of Symmetry: Reconstruction of a Three-Fold Symmetric Globular Protein by Broom, Aron, Doxey, Andrew C., Lobsanov, Yuri D., Berthin, Lisa G., Rose, David R., Howell, P. Lynne, McConkey, Brendan J., Meiering, Elizabeth M.

“…The high frequency of internal structural symmetry in common protein folds is presumed to reflect their evolutionary origins from the repetition and fusion of…”
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Effects of Bacterial ACC Deaminase on Brassica napus Gene Expression by STEARNS, Jennifer C, WOODY, Owen Z, MCCONKEY, Brendan J, GLICK, Bernard R

“…Plants in association with plant growth-promoting rhizobacteria can benefit from lower plant ethylene levels through the action of the bacterial enzyme…”
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The evolution of the class A scavenger receptors by Whelan, Fiona J, Meehan, Conor J, Golding, G Brian, McConkey, Brendan J, Bowdish, Dawn M E

“…The class A scavenger receptors are a subclass of a diverse family of proteins defined based on their ability to bind modified lipoproteins. The 5 members of…”
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Apoptosis induction by eIF5A1 involves activation of the intrinsic mitochondrial pathway by Sun, Zhong, Cheng, Zhenyu, Taylor, Catherine A., McConkey, Brendan J., Thompson, John E.

“…The regulatory role of eukaryotic translation initiation factor 5A1 (eIF5A1) in apoptosis was examined using HT‐29 and HeLa S3 cells. eIF5A is the only known…”
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Transcriptomic and barrier responses of human airway epithelial cells exposed to cannabis smoke by Aguiar, Jennifer A., Huff, Ryan D., Tse, Wayne, Stämpfli, Martin R., McConkey, Brendan J., Doxey, Andrew C., Hirota, Jeremy A.

“…Globally, many jurisdictions are legalizing or decriminalizing cannabis, creating a potential public health issue that would benefit from experimental evidence…”
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Nuclear Targeting of Methyl-Recycling Enzymes in Arabidopsis thaliana Is Mediated by Specific Protein Interactions by Lee, Sanghyun, Doxey, Andrew C., McConkey, Brendan J., Moffatt, Barbara A.

“…Numerous transmethylation reactions are required for normal plant growth and development. S-adenosylhomocysteine hydrolase （SAHH） and adenosine kinase （ADK）…”
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Importance of solvent accessibility and contact surfaces in modeling side-chain conformations in proteins by Eyal, Eran, Najmanovich, Rafael, Mcconkey, Brendan J., Edelman, Marvin, Sobolev, Vladimir

“…Contact surface area and chemical properties of atoms are used to concurrently predict conformations of multiple amino acid side chains on a fixed protein…”
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The origin recognition complex protein family by Duncker, Bernard P, Chesnokov, Igor N, McConkey, Brendan J

“…Origin recognition complex (ORC) proteins were first discovered as a six-subunit assemblage in budding yeast that promotes the initiation of DNA replication…”
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Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke by Huff, Ryan D, Aguiar, Jennifer A, Tse, Wayne, Stämpfli, Martin R, McConkey, Brendan J, Doxey, Andrew C, Hirota, Jeremy A

“…http://bit.ly/2qiSQhH…”
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Horizontal gene transfer contributed to the evolution of extracellular surface structures: the freshwater polyp Hydra is covered by a complex fibrous cuticle containing glycosaminoglycans and proteins of the PPOD and SWT (sweet tooth) families by Böttger, Angelika, Doxey, Andrew C, Hess, Michael W, Pfaller, Kristian, Salvenmoser, Willi, Deutzmann, Rainer, Geissner, Andreas, Pauly, Barbara, Altstätter, Johannes, Münder, Sandra, Heim, Astrid, Gabius, Hans-Joachim, McConkey, Brendan J, David, Charles N

“…The single-cell layered ectoderm of the fresh water polyp Hydra fulfills the function of an epidermis by protecting the animals from the surrounding medium…”
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Discrimination of Native Protein Structures Using Atom-Atom Contact Scoring by McConkey, Brendan J., Sobolev, Vladimir, Edelman, Marvin

“…We introduce a method for discriminating correctly folded proteins from well designed decoy structures using atom-atom and atom-solvent contact surfaces. The…”
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Identification of Bacterial Proteins Mediating the Interactions Between Pseudomonas putida UW4 and Brassica napus (Canola) by Cheng, Zhenyu, Duan, Jin, Hao, Youai, McConkey, Brendan J, Glick, Bernard R

“…The influence of canola root exudates on the proteome of Pseudomonas putida UW4 and the mutant strain P. putida UW4/AcdS-, which lacks a functional…”
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Monitoring Microbial Populations and Antibiotic Resistance Gene Enrichment Associated with Arctic Waste Stabilization Ponds by Gromala, Monica, Neufeld, Josh D, McConkey, Brendan J

“…Wastewater management in the Canadian Arctic is challenging due to climate extremes, small population sizes, and lack of conventional infrastructure for…”
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TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis by Meininger, Vincent, Spiegelman, Dan, Salachas, Francois, Dupre, Nicolas, Dion, Patrick, Velde, Christine Vande, Pradat, Pierre-Francois, Kabashi, Edor, Bouchard, Jean-Pierre, Lacomblez, Lucette, Valdmanis, Paul N, McConkey, Brendan J, Camu, William, Pochigaeva, Ksenia, Rouleau, Guy A

“…Recently, TDP-43 was identified as a key component of ubiquitinated aggregates in amyotrophic lateral sclerosis (ALS), an adult-onset neurological disorder…”
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Pollux: platform independent error correction of single and mixed genomes by Marinier, Eric, Brown, Daniel G, McConkey, Brendan J

“…Second-generation sequencers generate millions of relatively short, but error-prone, reads. These errors make sequence assembly and other downstream projects…”
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Structural models predict a significantly higher binding affinity between the NblA protein of cyanophage Ma-LMM01 and the phycocyanin of Microcystis aeruginosa NIES-298 compared to the host homolog by Meza-Padilla, Isaac, McConkey, Brendan J, Nissimov, Jozef I

“…Abstract Horizontal gene transfer events between viruses and hosts are widespread across the virosphere. In cyanophage-host systems, such events often involve…”
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