Search Results - "McCombie, R"

De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability by McCarthy, S E, Gillis, J, Kramer, M, Lihm, J, Yoon, S, Berstein, Y, Mistry, M, Pavlidis, P, Solomon, R, Ghiban, E, Antoniou, E, Kelleher, E, O'Brien, C, Donohoe, G, Gill, M, Morris, D W, McCombie, W R, Corvin, A

“…Schizophrenia is a serious psychiatric disorder with a broadly undiscovered genetic etiology. Recent studies of de novo mutations (DNMs) in schizophrenia and…”
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Distinct p53 genomic binding patterns in normal and cancer-derived human cells by Botcheva, Krassimira, McCorkle, Sean R., McCombie, W.R., Dunn, John J., Anderson, Carl W.

“…We report here genome-wide analysis of the tumor suppressor p53 binding sites in normal human cells. 743 high-confidence ChIP-seq peaks representing putative…”
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DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan by Porteous, D J, Thomson, P A, Millar, J K, Evans, K L, Hennah, W, Soares, D C, McCarthy, S, McCombie, W R, Clapcote, S J, Korth, C, Brandon, N J, Sawa, A, Kamiya, A, Roder, J C, Lawrie, S M, McIntosh, A M, St Clair, D, Blackwood, D H

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Discovery of novel human breast cancer microRNAs from deep sequencing data by analysis of pri-microRNA secondary structures by Ryu, Seongho, Joshi, Natasha, McDonnell, Kevin, Woo, Jongchan, Choi, Hyejin, Gao, Dingcheng, McCombie, William R, Mittal, Vivek

“…MicroRNAs (miRNAs) are key regulators of gene expression and contribute to a variety of biological processes. Abnormal miRNA expression has been reported in…”
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708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits by Thomson, P A, Parla, J S, McRae, A F, Kramer, M, Ramakrishnan, K, Yao, J, Soares, D C, McCarthy, S, Morris, S W, Cardone, L, Cass, S, Ghiban, E, Hennah, W, Evans, K L, Rebolini, D, Millar, J K, Harris, S E, Starr, J M, MacIntyre, D J, McIntosh, A M, Watson, J D, Deary, I J, Visscher, P M, Blackwood, D H, McCombie, W R, Porteous, D J

“…A balanced t(1;11) translocation that transects the Disrupted in schizophrenia 1 (DISC1) gene shows genome-wide significant linkage for schizophrenia and…”
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Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett’s esophagus by Streppel, M M, Lata, S, DelaBastide, M, Montgomery, E A, Wang, J S, Canto, M I, Macgregor-Das, A M, Pai, S, Morsink, F H M, Offerhaus, G J, Antoniou, E, Maitra, A, McCombie, W R

“…The incidence of Barrett’s esophagus (BE)-associated esophageal adenocarcinoma (EAC) is increasing. Next-generation sequencing (NGS) provides an unprecedented…”
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Pigeonpea genomics initiative (PGI): an international effort to improve crop productivity of pigeonpea (Cajanus cajan L.) by Varshney, R. K, Penmetsa, R. V, Dutta, S, Kulwal, P. L, Saxena, R. K, Datta, S, Sharma, T. R, Rosen, B, Carrasquilla-Garcia, N, Farmer, A. D, Dubey, A, Saxena, K. B, Gao, J, Fakrudin, B, Singh, M. N, Singh, B. P, Wanjari, K. B, Yuan, M, Srivastava, R. K, Kilian, A, Upadhyaya, H. D, Mallikarjuna, N, Town, C. D, Bruening, G. E, He, G, May, G. D, McCombie, R, Jackson, S. A, Singh, N. K, Cook, D. R

“…Pigeonpea (Cajanus cajan), an important food legume crop in the semi-arid regions of the world and the second most important pulse crop in India, has an…”
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Management, Analyses, and Distribution of the MaizeCODE Data on the Cloud by Wang, Liya, Lu, Zhenyuan, delaBastide, Melissa, Van Buren, Peter, Wang, Xiaofei, Ghiban, Cornel, Regulski, Michael, Drenkow, Jorg, Xu, Xiaosa, Ortiz-Ramirez, Carlos, Marco, Cristina F, Goodwin, Sara, Dobin, Alexander, Birnbaum, Kenneth D, Jackson, David P, Martienssen, Robert A, McCombie, William R, Micklos, David A, Schatz, Michael C, Ware, Doreen H, Gingeras, Thomas R

“…MaizeCODE is a project aimed at identifying and analyzing functional elements in the maize genome. In its initial phase, MaizeCODE assayed up to five tissues…”
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Rapid selection using G418 of high copy number transformants of Pichia pastoris for high-level foreign gene expression by Scorer, C.A, Clare, J.J, McCombie, W.R, Romanos, M.A, Sreekrishna, K

“…Pichia pastoris is a methylotrophic yeast increasingly important in the production of therapeutic proteins. Expression vectors are based on the…”
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Genetic Definition and Sequence Analysis of Arabidopsis Centromeres by Copenhaver, Gregory P., Nickel, Kathryn, Kuromori, Takashi, Benito, Maria-Ines, Kaul, Samir, Lin, Xiaoying, Bevan, Michael, Murphy, George, Harris, Barbara, Parnell, Laurence D., McCombie, W. Richard, Martienssen, Robert A., Marra, Marco, Preuss, Daphne

“…High-precision genetic mapping was used to define the regions that contain centromere functions on each natural chromosome in Arabidopsis thaliana. These…”
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Evolution and microsynteny of the apyrase gene family in three legume genomes by Cannon, S.B, McCombie, W.R, Sato, S, Tabata, S, Denny, R, Palmer, L, Katari, M, Young, N.D, Stacey, G

“…Apyrases have been suggested to play important roles in plant nutrition, photomorphogenesis, and nodulation. To help trace the evolution of these genes in the…”
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Differential methylation of genes and retrotransposons facilitates shotgun sequencing of the maize genome by Martienssen, Robert A, Rabinowicz, Pablo D, Schutz, Kristin, Dedhia, Neilay, Yordan, Cristina, Parnell, Laurence D, Stein, Lincoln, McCombie, W. Richard

“…The genomes of higher plants and animals are highly differentiated, and are composed of a relatively small number of genes and a large fraction of repetitive…”
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Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia by Teng, S, Thomson, P A, McCarthy, S, Kramer, M, Muller, S, Lihm, J, Morris, S, Soares, D C, Hennah, W, Harris, S, Camargo, L M, Malkov, V, McIntosh, A M, Millar, J K, Blackwood, D H, Evans, K L, Deary, I J, Porteous, D J, McCombie, W R

“…Schizophrenia (SCZ), bipolar disorder (BD) and recurrent major depressive disorder (rMDD) are common psychiatric illnesses. All have been associated with lower…”
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DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling by Martin, P-M, Stanley, R E, Ross, A P, Freitas, A E, Moyer, C E, Brumback, A C, Iafrati, J, Stapornwongkul, K S, Dominguez, S, Kivimäe, S, Mulligan, K A, Pirooznia, M, McCombie, W R, Potash, J B, Zandi, P P, Purcell, S M, Sanders, S J, Zuo, Y, Sohal, V S, Cheyette, B N R

“…Mice lacking DIX domain containing-1 (DIXDC1), an intracellular Wnt/β-catenin signal pathway protein, have abnormal measures of anxiety, depression and social…”
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An adipose tissue-specific beta-adrenergic receptor. Molecular cloning and down-regulation in obesity by MUZZIN, P, REVELLI, J.-P, KUKNE, F, GOCAYNE, J. D, MCCOMBIE, W. R, CRAIG VENTER, J, GIACOBINO, J.-P, FRASER, C. M

“…Clones encoding an atypical beta-adrenergic receptor were isolated from a rat brown adipose tissue cDNA library. This receptor expressed in Chinese hamster…”
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The molecular biology of the flavin-containing monooxygenases of man by Phillips, Ian R., Dolphin, Colin T., Clair, Philippe, Hadley, Mark R., Hutt, Andrew J., McCombie, Richard R., Smith, Robert L., Shephard, Elizabeth A.

“…cDNA clones encoding five distinct members of the FMO family of man (FMOs 1,2, 3, 4 and 5) were isolated by a combination of library screening and reverse…”
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Gene Trap Tagging of PROLIFERA, an Essential MCM2-3-5-Like Gene in Arabidopsis by Springer, Patricia S., McCombie, W. Richard, Sundaresan, Venkatesan, Martienssen, Robert A.

“…Gene trap transposon mutagenesis can identify essential genes whose functions in later development are obscured by an early lethal phenotype. In higher plants,…”
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zA map for sequence analysis of the Arabidopsis thaliana genome by MARRA, M, KUCABA, T, MCCOMBIE, W. R, MCDONALD, K, MCPHERSON, J, MUDD, N, PARNELL, L, SCHEIN, J, SEIM, R, SHELBY, P, WATERSTON, R, WILSON, R, SEKHON, M, HILLIER, L, MARTIENSSEN, R, CHINWALLA, A, CROCKETT, J, FEDELE, J, GROVER, H, GUND, C

“…Arabidopsis thaliana has emerged as a model system for studies of plant genetics and development, and its genome has been targeted for sequencing by an…”
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Iatrogenic Creutzfeldt-Jakob disease : an example of the interplay between ancient genes and modern medicine by BROWN, P, CERVENAKOVA, L, GRAUPERA, G, LIGAN, J, GAJDUSEK, D. C, GOLDFARB, L. G, MCCOMBIE, W. R, RUBENSTEIN, R, WILL, R. G, POCCHIARI, M, MARTINEZ-LAGE, J. F, SCALICI, C, MASULLO, C

“…We tested DNA from 15 centrally infected cases of iatrogenic Creutzfeldt-Jakob disease (CJD) (dura mater or corneal homografts and stereotactic EEG…”
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The First Plant Genome by Martienssen, R., McCombie, W.R.

“…The sequence of the model plant Arabidopsis thaliana was published last year. A. thaliana is an annual cruciferous weed, related to mustards and cabbages, and…”
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