Search Results - "McClure, R. F."

IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms by Pardanani, A, Lasho, T L, Finke, C M, Mai, M, McClure, R F, Tefferi, A

“…Bone marrow DNA was screened for isocitrate dehydrogenase ( IDH ) mutations in 200 patients with chronic ( n =166) or blast ( n =34) phase myeloproliferative…”
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IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F by Tefferi, A, Jimma, T, Sulai, N H, Lasho, T L, Finke, C M, Knudson, R A, McClure, R F, Pardanani, A

“…Isocitrate dehydrogenase ( IDH ) mutations are frequent in blast-phase myeloproliferative neoplasms and might therefore contribute to leukemic transformation…”
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IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis by Tefferi, A, Lasho, T L, Abdel-Wahab, O, Guglielmelli, P, Patel, J, Caramazza, D, Pieri, L, Finke, C M, Kilpivaara, O, Wadleigh, M, Mai, M, McClure, R F, Gilliland, D G, Levine, R L, Pardanani, A, Vannucchi, A M

“…In a multi-institutional collaborative project, 1473 patients with myeloproliferative neoplasms (MPN) were screened for isocitrate dehydrogenase 1 ( IDH1 )/…”
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A phase-2 trial of low-dose pomalidomide in myelofibrosis by Begna, K H, Mesa, R A, Pardanani, A, Hogan, W J, Litzow, M R, McClure, R F, Tefferi, A

“…In a previous study, we reported on the safety and efficacy of low-dose (0.5 mg) pomalidomide and prednisone and pomalidomide alone (2 mg/day), for the…”
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Risk stratification for survival and leukemic transformation in essential thrombocythemia: a single institutional study of 605 patients by GANGAT, N, WOLANSKYJ, A. P, MCCLURE, R. F, LI, C.-Y, SCHWAGER, S, WU, W, TEFFERI, A

“…Unlike the case with thrombosis, prognostic models for survival and leukemic transformation (LT) in essential thrombocythemia (ET) are not available. Among 605…”
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JAK2 V617F is a rare finding in de novo acute myeloid leukemia, but STAT3 activation is common and remains unexplained by STEENSMA, D. P, MCCLURE, R. F, KARP, J. E, TEFFERI, A, LASHO, T. L, POWELL, H. L, DEWALD, G. W, KAUFMANN, S. H

“…Signal transducer and activator of transcription (STAT) proteins are phosphorylated and activated by Janus kinases (JAKs). Recently, several groups identified…”
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Recurrent IDH mutations in high-risk myelodysplastic syndrome or acute myeloid leukemia with isolated del(5q) by Pardanani, A, Patnaik, M M, Lasho, T L, Mai, M, Knudson, R A, Finke, C, Ketterling, R P, McClure, R F, Tefferi, A

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Novel FISH probes designed to detect IGK-MYC and IGL-MYC rearrangements in b-cell lineage malignancy identify a new breakpoint cluster region designated BVR2 by EINERSON, R. R, LAW, M. E, BLAIR, H. E, KURTIN, P. J, MCCLURE, R. F, KETTERLING, R. P, FLYNN, H. C, DOGAN, A, REMSTEIN, E. D

“…Detection of translocations involving MYC at 8q24.1 in B-cell lineage malignancies (BCL) is important for diagnostic and prognostic purposes. However, routine…”
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Janus kinase 2 (V617F) mutation status, signal transducer and activator of transcription-3 phosphorylation and impaired neutrophil apoptosis in myelofibrosis with myeloid metaplasia by MESA, R. A, TEFFERI, A, LASHO, T. S, LOEGERING, D, MCCLURE, R. F, POWELL, H. L, DAI, N. T, STEENSMA, D. P, KAUIMANN, S. H

“…An activating point mutation in Janus kinase 2 (JAK2 V617F) was recently identified in myelofibrosis with myeloid metaplasia (MMM). To further elucidate the…”
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Isolated isochromosome 17q: a distinct type of mixed myeloproliferative disorder/myelodysplastic syndrome with an aggressive clinical course by McClure, R. F., Dewald, G. W., Hoyer, J. D., Hanson, C. A.

“…A clinicopathologic study was performed on 15 patients with haematological malignancies in which isochromosome 17q [i(17q)] was the sole structural chromosome…”
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Use of multiple displacement amplification to amplify genomic DNA before sequencing of the α and β haemoglobin genes by Mai, M, Hoyer, J D, McClure, R F

“…Aims: To evaluate the technique of multiple displacement amplification (MDA) for whole genome amplification from small volume blood samples before sequencing…”
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Clonal mast cell disease not meeting WHO criteria for diagnosis of mastocytosis: clinicopathologic features and comparison with indolent mastocytosis by Pardanani, A, Chen, D, Abdelrahman, R A, Reichard, K K, Zblewski, D, Wood, A J, McClure, R F, Butterfield, J H, Hanson, C A, Tefferi, A

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Serous borderline tumor of the paratestis: A report of seven cases by MCCLURE, Rebecca F, KEENEY, Gary L, SEBO, Thomas J, CHEVILLE, John C

“…We report the clinical, morphologic, immunophenotypic, and ploidy findings of seven cases of serous borderline tumor of the paratestis. Mean patient age was 56…”
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Validation of immunoglobulin gene rearrangement detection by PCR using commercially available BIOMED-2 primers by McClure, R F, Kaur, P, Pagel, E, Ouillette, P D, Holtegaard, C E, Treptow, C L, Kurtin, P J

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Multiple myeloma presenting initially as a solitary pleural effusion later complicated by malignant plasmacytic ascites by Inoue, Yoshio, Chua, Kathrina, McClure, Rebecca F., Jimenez, Manuel C., Gocke, Christopher D., Badros, Ashraf Z., Takebe, Naoko

“…A pleural effusion is a rare presenting feature of multiple myeloma and can be a complication of myelomatous ascites as well. An additional unique feature of…”
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Constitutive Fas Ligand Gene Transcription in Sertoli Cells Is Regulated By Sp1 by McClure, R F, Heppelmann, C J, Paya, C V

“…The transcriptional regulation of the Fas ligand (FasL) gene in Sertoli cells was investigated, as these cells are known to have constitutive expression of…”
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Videogame playing and psychopathology by McClure, R F, Mears, F G

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Age and Video Game Playing by McClure, Robert F.

“…This study compared attitudes of 216 high school students and 138 mature adults toward playing video-computer games. Younger subjects were more comfortable…”
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Towards quick identification of students with problems by McClure, R F

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Do Students Studying Therapy Have More Problems? by McClure, Robert F.

“…This study examined several questions on whether graduate students studying therapy reported more personal counseling or traumas than other students. The 66…”
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