Search Results - "McClure, Allison W"

Role of Polarized G Protein Signaling in Tracking Pheromone Gradients by McClure, Allison W., Minakova, Maria, Dyer, Jayme M., Zyla, Trevin R., Elston, Timothy C., Lew, Daniel J.

“…Yeast cells track gradients of pheromones to locate mating partners. Intuition suggests that uniform distribution of pheromone receptors over the cell surface…”
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease by Canal, Berta, Fujisawa, Ryo, McClure, Allison W, Deegan, Tom D, Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Drury, Lucy S, Bertolin, Agustina P, Zeng, Jingkun, Beale, Rupert, Howell, Michael, Labib, Karim, Diffley, John F X

“…SARS-CoV-2 is responsible for COVID-19, a human disease that has caused over 2 million deaths, stretched health systems to near-breaking point and endangered…”
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Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation by McClure, Allison W, Diffley, John Fx

“…The Rad53 DNA checkpoint protein kinase plays multiple roles in the budding yeast cell response to DNA replication stress. Key amongst these is its enigmatic…”
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase by Basu, Souradeep, Mak, Tiffany, Ulferts, Rachel, Wu, Mary, Deegan, Tom, Fujisawa, Ryo, Tan, Kang Wei, Lim, Chew Theng, Basier, Clovis, Canal, Berta, Curran, Joseph F, Drury, Lucy S, McClure, Allison W, Roberts, Emma L, Weissmann, Florian, Zeisner, Theresa U, Beale, Rupert, Cowling, Victoria H, Howell, Michael, Labib, Karim, Diffley, John F X

“…The COVID-19 pandemic has presented itself as one of the most critical public health challenges of the century, with SARS-CoV-2 being the third member of the…”
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease by Canal, Berta, McClure, Allison W, Curran, Joseph F, Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Zeng, Jingkun, Bertolin, Agustina P, Milligan, Jennifer C, Basu, Souradeep, Drury, Lucy S, Deegan, Tom D, Fujisawa, Ryo, Roberts, Emma L, Basier, Clovis, Labib, Karim, Beale, Rupert, Howell, Michael, Diffley, John F X

“…SARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world causing a deadly pandemic with tremendous social and economic costs…”
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Cell Polarity: Netrin Calms an Excitable System by McClure, Allison W., Lew, Daniel J.

“…In a tractable model for cell invasion, the Caenorhabditis elegans anchor cell migrates through basement membranes towards a polarity cue provided by netrin. A…”
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A DNA replication fork-centric view of the budding yeast DNA damage response by McClure, Allison W., Canal, Berta, Diffley, John F.X.

“…The DNA damage response (DDR) checkpoint is activated when DNA is damaged or when DNA replication forks stall. The DDR checkpoint plays a critical role in…”
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Unwinding of a eukaryotic origin of replication visualized by cryo-EM by Henrikus, Sarah S., Gross, Marta H., Willhoft, Oliver, Pühringer, Thomas, Lewis, Jacob S., McClure, Allison W., Greiwe, Julia F., Palm, Giacomo, Nans, Andrea, Diffley, John F. X., Costa, Alessandro

“…To prevent detrimental chromosome re-replication, DNA loading of a double hexamer of the minichromosome maintenance (MCM) replicative helicase is temporally…”
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Mating in wild yeast: delayed interest in sex after spore germination by McClure, Allison W, Jacobs, Katherine C, Zyla, Trevin R, Lew, Daniel J

“…Studies of laboratory strains of have uncovered signaling pathways involved in mating, including information-processing strategies to optimize decisions to…”
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Author Correction: Unwinding of a eukaryotic origin of replication visualized by cryo-EM by Henrikus, Sarah S., Gross, Marta H., Willhoft, Oliver, Pühringer, Thomas, Lewis, Jacob S., McClure, Allison W., Greiwe, Julia F., Palm, Giacomo, Nans, Andrea, Diffley, John F. X., Costa, Alessandro

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To avoid a mating mishap, yeast focus and communicate by McClure, Allison W, Lew, Daniel J

“…During mating, yeast cells must perforate their rigid cell walls at the right place to allow cell-cell fusion. In this issue, Dudin et al. (2015; J. Cell Biol…”
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Imaging Polarization in Budding Yeast by McClure, Allison W, Wu, Chi-Fang, Johnson, Sam A, Lew, Daniel J

“…We describe methods for live-cell imaging of yeast cells that we have exploited to image yeast polarity establishment. As a rare event occurring on a fast…”
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