Search Results - "McCloskey, Nicholas S."
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PEMPS: a phylogenetic software tool to model the evolution of metabolic pathways
Published in BMC bioinformatics (18-07-2024)“…Metabolic pathways support the enzyme flux that converts input chemicals into energy and cellular building blocks. With a constant rate of input, steady-state…”
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Role of serotonin neurons in the dorsal raphe nucleus in heroin self-administration and punishment
Published in Neuropsychopharmacology (New York, N.Y.) (19-09-2024)“…One hallmark of substance use disorder is continued drug use despite negative consequences. When drug-taking behavior is punished with aversive stimuli, i.e…”
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Sex differences in ethanol consumption and drinking despite negative consequences following adolescent social isolation stress in male and female rats
Published in Physiology & behavior (01-11-2023)“…•Early life stress has sex- and model-dependent effects on adult ethanol intake.•Females show more overall and punishment-resistant ethanol intake than…”
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Role of α1-GABAA receptors in the serotonergic dorsal raphe nucleus in models of opioid reward, anxiety, and depression
Published in Journal of psychopharmacology (Oxford) (01-02-2024)“…Background: The serotonin (5-hydroxytryptamine (5-HT))-mediated system plays an important role in stress-related psychiatric disorders and substance abuse. Our…”
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Paradoxical anxiolytic effect of the ‘bath salt’ synthetic cathinone MDPV during early abstinence is inhibited by a chemokine CXCR4 or CCR5 receptor antagonist
Published in Drug and alcohol dependence (01-01-2022)“…Chemokine CXCR4 and CCR5 receptors are best known as HIV co-entry receptors, but evidence that CXCR4 or CCR5 blockade reduces rewarding and locomotor-stimulant…”
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Role of α1-GABA A receptors in the serotonergic dorsal raphe nucleus in models of opioid reward, anxiety, and depression
Published in Journal of psychopharmacology (Oxford) (01-02-2024)“…The serotonin (5-hydroxytryptamine (5-HT))-mediated system plays an important role in stress-related psychiatric disorders and substance abuse. Our previous…”
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