Search Results - "McCloskey, Nicholas S."

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  1. 1

    PEMPS: a phylogenetic software tool to model the evolution of metabolic pathways by McCloskey, Nicholas S, Mammedova, Ayna, Liberles, David A

    Published in BMC bioinformatics (18-07-2024)
    “…Metabolic pathways support the enzyme flux that converts input chemicals into energy and cellular building blocks. With a constant rate of input, steady-state…”
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    Journal Article
  2. 2

    Role of serotonin neurons in the dorsal raphe nucleus in heroin self-administration and punishment by Li, Chen, McCloskey, Nicholas S, Inan, Saadet, Kirby, Lynn G

    Published in Neuropsychopharmacology (New York, N.Y.) (19-09-2024)
    “…One hallmark of substance use disorder is continued drug use despite negative consequences. When drug-taking behavior is punished with aversive stimuli, i.e…”
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  3. 3

    Sex differences in ethanol consumption and drinking despite negative consequences following adolescent social isolation stress in male and female rats by McElroy, Bryan D., Li, Chen, McCloskey, Nicholas S., Kirby, Lynn G.

    Published in Physiology & behavior (01-11-2023)
    “…•Early life stress has sex- and model-dependent effects on adult ethanol intake.•Females show more overall and punishment-resistant ethanol intake than…”
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  4. 4

    Role of α1-GABAA receptors in the serotonergic dorsal raphe nucleus in models of opioid reward, anxiety, and depression by Li, Chen, McElroy, Bryan D, Phillips, Jared, McCloskey, Nicholas S, Shi, Xiangdang, Unterwald, Ellen M, Kirby, Lynn G

    Published in Journal of psychopharmacology (Oxford) (01-02-2024)
    “…Background: The serotonin (5-hydroxytryptamine (5-HT))-mediated system plays an important role in stress-related psychiatric disorders and substance abuse. Our…”
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  5. 5

    Paradoxical anxiolytic effect of the ‘bath salt’ synthetic cathinone MDPV during early abstinence is inhibited by a chemokine CXCR4 or CCR5 receptor antagonist by Simmons, Steven J., Oliver, Chicora F., McCloskey, Nicholas S., Reitz, Allen B., Nayak, Sunil U., Watson, Mia N., Rawls, Scott M.

    Published in Drug and alcohol dependence (01-01-2022)
    “…Chemokine CXCR4 and CCR5 receptors are best known as HIV co-entry receptors, but evidence that CXCR4 or CCR5 blockade reduces rewarding and locomotor-stimulant…”
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  6. 6

    Role of α1-GABA A receptors in the serotonergic dorsal raphe nucleus in models of opioid reward, anxiety, and depression by Li, Chen, McElroy, Bryan D, Phillips, Jared, McCloskey, Nicholas S, Shi, Xiangdang, Unterwald, Ellen M, Kirby, Lynn G

    Published in Journal of psychopharmacology (Oxford) (01-02-2024)
    “…The serotonin (5-hydroxytryptamine (5-HT))-mediated system plays an important role in stress-related psychiatric disorders and substance abuse. Our previous…”
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    Journal Article